The DOI matches its Crossref record; 21 of the 28 references it cites were found in a registry or an index.
Prevalence of Pre-Diabetes and Its Association With Clustering of Cardiometabolic Risk Factors and Hyperinsulinemia Among U.S. Adolescents
Open accessAbstract
OBJECTIVE—Impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT) are considered to constitute “pre-diabetes.” We estimated the prevalence of IFG, IGT, and pre-diabetes among U.S. adolescents using data from a nationally representative sample. RESEARCH DESIGN AND METHODS—We analyzed data from participants aged 12–19 years in the National Health and Nutrition Examination Survey 2005–2006. We used fasting plasma glucose and 2-h glucose during an oral glucose tolerance test to assess the prevalence of IFG, IGT, and pre-diabetes and used the log-binomial model to estimate the prevalence ratios (PRs) and 95% CIs. RESULTS—The unadjusted prevalences of IFG, IGT, and pre-diabetes were 13.1, 3.4, and 16.1%, respectively. Boys had a 2.4-fold higher prevalence of pre-diabetes than girls (95% CI 1.3–4.3). Non-Hispanic blacks had a lower rate than non-Hispanic whites (PR 0.6, 95% CI 0.4–0.9). Adolescents aged 16–19 years had a lower rate than those aged 12–15 years (0.6, 0.4–0.9). Overweight adolescents had a 2.6-fold higher rate than those with normal weight (1.3–5.1). Adolescents with two or more cardiometabolic risk factors had a 2.7-fold higher rate than those with none (1.5–4.8). Adolescents with hyperinsulinemia had a fourfold higher prevalence (2.2–7.4) than those without. Neither overweight nor number of cardiometabolic risk factors was significantly associated with pre-diabetes after adjustment for hyperinsulinemia. CONCLUSIONS—Pre-diabetes was highly prevalent among adolescents. Hyperinsulinemia was independently associated with pre-diabetes and may account for the association of overweight and clustering of cardiometabolic risk factors with pre-diabetes.
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“The number of youth with elevated fasting blood sugar increased 87% from 1999–2000 to 2005–2006”
From Lack of Exercise Is a Major Cause of Chronic Diseases (2012) · cites this paper as [318]
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Flagged first, then by citations
7 of the 28 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
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- Li C, Ford ES, McGuire LC, Mokdad AH, Little RR, Reaven GM: Trends in hyperinsulinemia among nondiabetic adults in the U.S. Diabetes Care 29:2396–2402, 2006 · DOI
Cited by
Sorted by citations
Lack of Exercise Is a Major Cause of Chronic Diseases
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Metadata
- Authors
- Li, C., Ford, E. S., Zhao, G., & Mokdad, A. H.
- Affiliations
- Centers for Disease Control and Prevention (US)
- University of Washington (US)
- Corresponding author
- Li, Chaoyang
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2009-02-01
- Volume
- 32
- Issue
- 2
- Pages
- 342-347
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- PMC
- PMC2628705
- OpenAlex
- W1978039317
- Cited by
- 340
- References
- 28
- Citations by year
- 2026: 5 · 2025: 6 · 2024: 8 · 2023: 8 · 2022: 8 · 2021: 13 · 2020: 13 · 2019: 13 · 2018: 18 · 2017: 27 · 2016: 47 · 2015: 46 · 2014: 31 · 2013: 28 · 2012: 25
- FWCI
- 10.64
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc-nd
- Locations
- Diabetes Care (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- prediabetes, adolescents, impaired fasting glucose, impaired glucose tolerance, hyperinsulinemia, cardiometabolic risk factors, risk factor clustering, overweight, prevalence, sex differences, racial differences, fasting blood glucose, oral glucose tolerance test
- MeSH terms
- Adolescent, Blood Glucose, Child, Fasting, Female, Heart Diseases, Humans, Hyperinsulinism, Interviews as Topic, Life Style, Male, Metabolic Diseases, Nutrition Surveys, Prediabetic State, Risk Factors, Sex Characteristics, United States, Prevalence, Glucose Intolerance, Racial Groups, Young Adult
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