The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Impact of Chronic Kidney Disease on Survival After Amputation in Individuals With Diabetes
Open accessAbstract
OBJECTIVE: To identify factors that influence survival after diabetes-related amputations. RESEARCH DESIGN AND METHODS: We abstracted medical records of 1,043 hospitalized subjects with diabetes and a lower-extremity amputation from 1 January to 31 December 1993 in six metropolitan statistical areas in south Texas. We identified mortality in the 10-year period after amputation from death certificate data. Diabetes was verified using World Health Organization criteria. Amputations were identified by ICD-9-CM codes 84.11–84.18 and categorized as foot, below-knee amputation, and above-knee amputation and verified by reviewing medical records. We evaluated three levels of renal function: chronic kidney disease (CKD), hemodialysis, and no renal disease. We defined CKD based on a glomerular filtration rate <60 ml/min and hemodialysis from Current Procedural Terminology (CPT) codes (90921, 90925, 90935, and 90937). We used χ2 for trend and Cox regression analysis to evaluate risk factors for survival after amputation. RESULTS: Patients with CKD and dialysis had more below-knee amputations and above-knee amputations than patients with no renal disease (P < 0.01). Survival was significantly higher in patients with no renal impairment (P < 0.01). The Cox regression indicated a 290% increase in hazard for death for dialysis treatment (hazard ratio [HR] 3.9, 95% CI 3.07–5.0) and a 46% increase for CKD (HR 1.46, 95% CI 1.21–1.77). Subjects with an above-knee amputation had a 167% increase in hazard (HR 2.67, 95% CI 2.14–3.34), and below-knee amputation patients had a 67% increase in hazard for death. CONCLUSIONS: Survival after amputation is lower in diabetic patients with CKD, dialysis, and high-level amputations.
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Levey, A. S., Bosch, J. P., Lewis, J. B., Greene, T., Rogers, N., Roth, D., & for the Modification of Diet in Renal Disease Study Group* (1999) · Annals of Internal Medicine · doi:10.7326/0003-4819-130-6-199903160-00002 · Cited by 15,079
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Self-citationArmstrong, D. G., Swerdlow, M. A., Armstrong, A. A., Conte, M. S., Padula, W. V., & Bus, S. A. (2020) · Journal of Foot and Ankle Research · doi:10.1186/s13047-020-00383-2 · Cited by 975
Current challenges and opportunities in the prevention and management of diabetic foot ulcers.
Jeffcoate, W. J., Vileikyte, L., Boyko, E. J., Armstrong, D. G., & Boulton, A. J. M. (2018) · Diabetes Care · doi:10.2337/dc17-1836 · Cited by 475
Self-citationThorud, J. C., Plemmons, B., Buckley, C. J., Shibuya, N., & Jupiter, D. C. (2016) · The Journal of Foot and Ankle Surgery · doi:10.1053/j.jfas.2016.01.012 · Cited by 331
Short and Long Term Mortality Rates after a Lower Limb Amputation
Fortington, L. V., Geertzen, J. H. B., van Netten, J. J., Postema, K., Rommers, G. M., & Dijkstra, P. U. (2013) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2013.03.024 · Cited by 286
Metadata
- Authors
- Lavery, L. A., Hunt, N. A., Ndip, A., Lavery, D. C., Van Houtum, W., & Boulton, A. J. M.
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2010-08-25
- Volume
- 33
- Issue
- 11
- Pages
- 2365-2369
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- OpenAlex
- W2152909003
- Cited by
- 217
- References
- 1
- FWCI
- 5.94
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Lavery, L. A., Hunt, N. A., Ndip, A., Lavery, D. C., Van Houtum, W., & Boulton, A. J. M. (2010). Impact of Chronic Kidney Disease on Survival After Amputation in Individuals With Diabetes. Diabetes Care. https://doi.org/10.2337/dc10-1213
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