CoChat
Sign Up
Cited by 147Celiac Disease Research and ManagementDiabetes and associated disordersDiabetes Management and Research

Prevalence of Celiac Disease in 52,721 Youth With Type 1 Diabetes: International Comparison Across Three Continents

Open access
Craig, Maria E., Prinz, Nicole, Boyle, Claire T., Campbell, Fiona M., Jones, Timothy W., Hofer, Sabine E., Simmons, Jill H., Holman, Naomi +12 more·2017·Diabetes Care
DOI 10.2337/dc16-2508PMC PMC6463736
Open this paper in CoChat — free account

Abstract

Objective Celiac disease (CD) has a recognized association with type 1 diabetes. We examined international differences in CD prevalence and clinical characteristics of youth with coexisting type 1 diabetes and CD versus type 1 diabetes only. Research design and methods Data sources were as follows: the Prospective Diabetes Follow-up Registry (DPV) (Germany/Austria); the T1D Exchange Clinic Network (T1DX) (U.S.); the National Paediatric Diabetes Audit (NPDA) (U.K. [England/Wales]); and the Australasian Diabetes Data Network (ADDN) (Australia). The analysis included 52,721 youths 1c , height SD score [SDS], overweight/obesity) and type 1 diabetes/CD versus type 1 diabetes, adjusting for sex, age, and diabetes duration. Results Biopsy-confirmed CD was present in 1,835 youths (3.5%) and was diagnosed at a median age of 8.1 years (interquartile range 5.3-11.2 years). Diabetes duration at CD diagnosis was 1-2 years in 18% of youths, >3-5 years in 23% of youths, and >5 years in 17% of youths. CD prevalence ranged from 1.9% in the T1DX to 7.7% in the ADDN and was higher in girls than boys (4.3% vs. 2.7%, P P P P P 1c values were comparable: 8.3 ± 1.5% (67 ± 17 mmol/mol) versus 8.4 ± 1.6% (68 ± 17 mmol/mol). Conclusions CD is a common comorbidity in youth with type 1 diabetes. Differences in CD prevalence may reflect international variation in screening and diagnostic practices, and/or CD risk. Although glycemic control was not different, the lower height SDS supports close monitoring…

Integrity signals

Registry

Crossref · 10.2337/dc16-2508

Cites

35 of 35 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

3 of the 38 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Related

Authors
Craig, M. E., Prinz, N., Boyle, C. T., Campbell, F. M., Jones, T. W., Hofer, S. E., Simmons, J. H., Holman, N., Tham, E., Fröhlich-Reiterer, E., DuBose, S., Thornton, H., King, B., Maahs, D. M., Holl, R. W., Warner, J. T., on behalf of the Australasian Diabetes Data Network (ADDN), the T1D Exchange Clinic Network (T1DX), the National Paediatric Diabetes Audit (NPDA) and the Royal College of Paediatrics and Child Health, & the Prospective Diabetes Follow-up Registry (DPV) initiative
Affiliations
  • The University of Sydney (AU)
  • Universität Ulm (DE)
  • Jaeb Center for Health Research (US)
  • Leeds Teaching Hospitals NHS Trust (GB)
  • The Kids Research Institute Australia (AU)
  • Innsbruck Medical University (AT)
  • Vanderbilt University Medical Center (US)
  • University of Glasgow (GB)
  • Women's and Children's Hospital (AU)
  • Medical University of Graz (AT)
  • Mersey and West Lancashire Teaching Hospitals NHS Trust (GB)
  • Hunter Medical Research Institute (AU)
  • Lucile Packard Children's Hospital (US)
  • Noah's Ark Children's Hospital for Wales (GB)
Corresponding author
Craig, Maria E.
ORCID
Venue
Diabetes Care
Publisher
American Diabetes Association
Published
2017-05-25
Volume
40
Issue
8
Pages
1034-1040
ISSN
  • 0149-5992 (ISSN-L)
  • 1935-5548
DOI
10.2337/dc16-2508
PMC
PMC6463736
OpenAlex
W2617859352
Cited by
146
References
38
Citations by year
2026: 9 · 2025: 14 · 2024: 11 · 2023: 14 · 2022: 20 · 2021: 23 · 2020: 17 · 2019: 14 · 2018: 17 · 2017: 6 · 2016: 1
FWCI
15.51
Type
journal article
Language
en
Open access
Licence
www.diabetesjournals.org/content/license (vor, 57 d)
Locations
  • Diabetes Care (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • UWA Profiles and Research Repository (UWA) (submittedVersion)
  • Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
  • ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (submittedVersion)
  • NOVA (University of Newcastle Australia) (submittedVersion)
Funders
  • German Federal Ministry for Education and Research
  • Leona M. and Harry B. Helmsley Charitable Trust
  • Royal College of Paediatrics and Child Health
  • JDRF Australia (17-2011-665)
  • National Health and Medical Research Council (APP1045777)
Topics
  • Health Sciences › Medicine › Gastroenterology › Celiac Disease Research and Management
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
Keywords
celiac disease, type 1 diabetes, youth, prevalence, comorbidities, HbA1c, glycemic control, height, obesity, sex differences, cross-national comparison, pediatric diabetes, non-white patients
MeSH terms
Adolescent, Australia, Blood Glucose, Celiac Disease, Child, Child, Preschool, Diabetes Mellitus, Type 1, England, Female, Follow-Up Studies, Germany, Glycated Hemoglobin, Humans, Male, Prospective Studies, Registries, Wales, Comorbidity, Prevalence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review