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The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

The Impact of Continuous Glucose Monitoring on Markers of Quality of Life in Adults With Type 1 Diabetes: Further Findings From the DIAMOND Randomized Clinical Trial

Polonsky, William H., Hessler, Danielle, Ruedy, Katrina J., Beck, Roy W.·2017·Diabetes Care
DOI 10.2337/dc17-0133
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Abstract

OBJECTIVE Continuous glucose monitoring (CGM) improves glycemic control, but data are inconclusive about its influence on quality of life (QOL). We investigated the impact of 24 weeks of CGM use on QOL in adults with type 1 diabetes (T1D) who use multiple daily insulin injections. RESEARCH DESIGN AND METHODS DIAMOND (Multiple Daily Injections and Continuous Glucose Monitoring in Diabetes) was a prospective randomized trial that assessed CGM versus self-monitoring of blood glucose (SMBG) only in 158 adults with poorly controlled T1D. At baseline and study end, participants completed QOL measures that assessed overall well-being (WHO-5), health status (EQ-5D-5L), diabetes distress (DDS), hypoglycemic fear (worry subscale of the HFS-II), and hypoglycemic confidence (HCS). At study end, CGM participants completed the CGM Satisfaction Survey. Linear regression analyses compared treatment group changes in QOL outcomes over time. Associations between CGM satisfaction and change in QOL outcomes and in glycemic control indices were assessed. RESULTS The CGM group demonstrated a greater increase in hypoglycemic confidence (P = 0.01) and a greater decrease in diabetes distress (P = 0.01) than the SMBG group. No significant group differences in well-being, health status, or hypoglycemic fear were observed. CGM satisfaction was not significantly associated with glycemic changes but was associated with reductions in diabetes distress (P < 0.001) and hypoglycemic fear (P = 0.02) and increases in hypoglycemic confidence (P < 0.001) and well-being (P = 0.01). CONCLUSIONS CGM contributes to significant improvement in diabetes-specific QOL (i.e., diabetes distress, hypoglycemic confidence) in adults with T1D, but not with QOL measures not specific to diabetes (i.e., well-being, health status). CGM satisfaction was associated with most of the QOL outcomes but not with glycemic outcomes.

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Crossref · 10.2337/dc17-0133

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Metadata

Authors
Polonsky, W. H., Hessler, D., Ruedy, K. J., & Beck, R. W.
Affiliations
  • University of California San Diego (US)
  • University of California, San Francisco (US)
  • Jaeb Center for Health Research (US)
Corresponding author
Polonsky, William H.
ORCID
Venue
Diabetes Care
Publisher
American Diabetes Association
Published
2017-04-07
Volume
40
Issue
6
Pages
736-741
ISSN
  • 0149-5992 (ISSN-L)
  • 1935-5548
DOI
10.2337/dc17-0133
OpenAlex
W2604156892
Cited by
346
References
22
Citations by year
2026: 41 · 2025: 35 · 2024: 50 · 2023: 45 · 2022: 39 · 2021: 33 · 2020: 33 · 2019: 35 · 2018: 30 · 2017: 5
FWCI
22.25
Type
journal article
Language
en
Open access
closed
Licence
www.diabetesjournals.org/content/license (vor, 45 d)
Locations
  • Diabetes Care (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
Keywords
continuous glucose monitoring, type 1 diabetes, quality of life, diabetes distress, self-monitoring of blood glucose, multiple daily insulin injections, glycemic control, adults with diabetes
MeSH terms
Adult, Aged, Anxiety, Blood Glucose, Diabetes Mellitus, Type 1, Female, Follow-Up Studies, Glycated Hemoglobin, Humans, Hypoglycemia, Hypoglycemic Agents, Insulin, Male, Middle Aged, Prospective Studies, Quality of Life, Blood Glucose Self-Monitoring, Biomarkers, Linear Models

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