The relationship between diabetes distress and clinical depression with glycemic control among patients with type 2 diabetes
Open accessAbstract
OBJECTIVE: To clarify previous findings that diabetes distress is related to glycemic control and self-management whereas measures of depression are not, using both binary and continuous measures of depression. RESEARCH DESIGN AND METHODS: Four hundred and sixty-three type 2 patients completed measures of diabetes distress (Diabetes Distress Scale [DDS]) and clinical depression (Patient Health Questionnaire 8 [PHQ8]). PHQ8 was employed as either a binary (≥10) or continuous variable. Dependent variables were A1C, diet, physical activity (PA), and medication adherence (MA). RESULTS: The inclusion of a binary or continuous PHQ8 score yielded no differences in any equation. DDS was significantly associated with A1C and PA, whereas PHQ8 was not; both DDS and PHQ8 were significantly and independently associated with diet and MA. CONCLUSIONS: The lack of association between depression and glycemic control is not due to the use of a binary measure of depression. Findings further clarify the significant association between distress and A1C.
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Diabetes distress is common and is separate from a psychological disorder.
“Diabetes distress is very common and is distinct from a psychological disorder (38–40).”
From Psychosocial care for people with diabetes: a position statement of the American Diabetes Association (2016) · cites this paper as [40]
Diabetes distress is very common.
“Diabetes distress is very common (321,(358)(359)(360).”
From 5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes:<i>Standards of Care in Diabetes—2023</i> (2023) · cites this paper as [359]
Diabetes distress is distinct from depression and has unique relationships with glycemic and other outcomes.
“While it shares some features with depression, diabetes distress is distinct and has unique relationships with glycemic and other outcomes (359,361).”
From 5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes:<i>Standards of Care in Diabetes—2023</i> (2023) · cites this paper as [359]
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Mood and metabolism: Anhedonia as a clinical target in Type 2 diabetes
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Type 2 Diabetes Mellitus Related Distress in Thailand
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Type 2 Diabetes: Model of Factors Associated with Glycemic Control
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- Authors
- Fisher, L., Glasgow, R. E., & Strycker, L. A.
- Affiliations
- University of California, San Francisco (US)
- Kaiser Permanente (US)
- Oregon Research Institute (US)
- Corresponding author
- Fisher, Lawrence
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2010-02-11
- Volume
- 33
- Issue
- 5
- Pages
- 1034-1036
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- PMC
- PMC2858170
- OpenAlex
- W2165573341
- Cited by
- 351
- References
- 14
- Citations by year
- 2026: 15 · 2025: 20 · 2024: 20 · 2023: 18 · 2022: 28 · 2021: 25 · 2020: 28 · 2019: 27 · 2018: 23 · 2017: 30 · 2016: 25 · 2015: 31 · 2014: 18 · 2013: 21 · 2012: 9
- FWCI
- 10.17
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Diabetes Care (publishedVersion, cc-by-nc-nd)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- eScholarship (California Digital Library) (submittedVersion, cc-by-nc-nd)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK035524, R01 DK-35524)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- diabetes distress, major depressive disorder, type 2 diabetes, glycemic control, HbA1c, diabetes self-management, physical activity, diet, medication adherence, PHQ-8, Diabetes Distress Scale
- MeSH terms
- Affective Symptoms, Aged, Major Depressive Disorder, Depressive Disorder, Major, Diabetes Mellitus, Type 2, Female, Health Status, Glycated Hemoglobin, Humans, Hyperglycemia, Male, Middle Aged, Predictive Value of Tests, Surveys and Questionnaires, Regression Analysis, Self Care
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