Cited by 191Diabetes Management and ResearchDiabetes Management and EducationDiabetes and associated disorders

Temporal Trends and Contemporary Use of Insulin Pump Therapy and Glucose Monitoring Among Children, Adolescents, and Adults With Type 1 Diabetes Between 1995 and 2017

van den Boom, Louisa, Karges, Beate, Auzanneau, Marie, Rami-Merhar, Birgit, Lilienthal, Eggert, von Sengbusch, Simone, Datz, Nicolin, Schröder, Carmen +6 more·2019·Diabetes Care

Abstract

Objective To investigate temporal trends and contemporary use of insulin pump therapy and glucose monitoring in type 1 diabetes. Research design and methods In a population-based study, we analyzed the use of insulin pump therapy, continuous glucose monitoring (CGM), and self-monitoring of blood glucose (SMBG) from 1995 to 2017 in patients with type 1 diabetes identified from the Diabetes Prospective Follow-up (DPV) database in Germany and Austria. Patients were stratified by age, sex, migration background, and country. Results Among 96,547 patients with type 1 diabetes (median age 17.9 years, 53% males), the percentage using insulin pump therapy increased from 1% in 1995 to 53% in 2017, with the highest rates in the youngest patients (92% in preschoolers, 74% in children, 56% in adolescents aged P P = 1.0) and for CGM use in all age-groups (all P = 1.0). Conclusions Since 1995, insulin pump use has continuously increased, and insulin pump therapy is now standard in patients aged <15 years. CGM use sharply rose in recent years, particularly in young children.

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Registry

Crossref · 10.2337/dc19-0345

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  • Restricting identification of type 1 diabetes to ages 18 to 55 may have inflated the proportion of pump users in both provinces with and without insulin pump funding programs, because insulin pump use is more common at younger ages.

    “our algorithm restricted identification of type 1 diabetes to individuals between the ages of 18 and 55 and, since insulin pump use is more common in younger ages, this might have also inflated the proportion of pump users in both provinces with and without insulin pump funding programs.”

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Authors
van den Boom, L., Karges, B., Auzanneau, M., Rami-Merhar, B., Lilienthal, E., von Sengbusch, S., Datz, N., Schröder, C., Kapellen, T., Laimer, M., Schmid, S. M., Müller, H., Wolf, J., & Holl, R. W.
Affiliations
  • Division of Pediatric Diabetes, Clementine Children’s Hospital, Frankfurt, Germany
  • RWTH Aachen University (DE)
  • Universität Ulm (DE)
  • Medical University of Vienna (AT)
  • St. Josef-Hospital (DE)
  • Department of Pediatrics and Adolescent Medicine, Division of Pediatric Endocrinology and Diabetes, University of Lübeck, Lübeck, Germany
  • Kinderkrankenhaus auf der Bult (DE)
  • Universitätsmedizin Greifswald (DE)
  • University Hospital Leipzig (DE)
  • University of Bern (CH)
  • German Center for Diabetes Research (DE)
  • Deutsche Klinik für Diagnostik (DE)
  • Department of Pediatric and Adolescent Medicine, St. Vincenz Hospital, Paderborn, Germany
Venue
Diabetes Care
Published
2019-09-05
Volume
42
Issue
11
Pages
2050-2056
ISSN
  • 0149-5992 (ISSN-L)
  • 1935-5548
OpenAlex
W2971929662
Cited by
191
References
36
Citations by year
2026: 15 · 2025: 11 · 2024: 16 · 2023: 30 · 2022: 46 · 2021: 39 · 2020: 32 · 2019: 1
FWCI
24.02
Type
journal article
Language
en
Open access
closed
Locations
  • Diabetes Care (publishedVersion)
  • PubMed (publishedVersion)
  • Bern Open Repository and Information System (University of Bern) (submittedVersion)
  • RWTH Publications (RWTH Aachen) (submittedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
Keywords
type 1 diabetes, insulin pump therapy, continuous glucose monitoring, self-monitoring of blood glucose, temporal trends, children and adolescents, sex differences, migration background
MeSH terms
Adolescent, Adult, Austria, Blood Glucose, Child, Child, Preschool, Diabetes Mellitus, Type 1, Female, Follow-Up Studies, Germany, Humans, Hypoglycemic Agents, Insulin Infusion Systems, Longitudinal Studies, Male, Prospective Studies, Blood Glucose Self-Monitoring, Databases, Factual, Young Adult, Insulins

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