Early Outcomes From the English National Health Service Diabetes Prevention Programme
Open accessAbstract
OBJECTIVE: To assess weight and HbA1c changes in the Healthier You: National Health Service Diabetes Prevention Programme (NHS DPP), the largest DPP globally to achieve universal population coverage. RESEARCH DESIGN AND METHODS: A service evaluation assessed intervention effectiveness for adults with nondiabetic hyperglycemia (HbA1c 42–47 mmol/mol [6.0–6.4%] or fasting plasma glucose 5.5–6.9 mmol/L) between program launch in June 2016 and December 2018, using prospectively collected, national service–level data in England. RESULTS: By December 2018, 324,699 people had been referred, 152,294 had attended the initial assessment, and 96,442 had attended at least 1 of 13 group-based intervention sessions. Allowing sufficient time to elapse, 53% attended an initial assessment, 36% attended at least one group-based session, and 19% completed the intervention (attended >60% of sessions). Of the 32,665 who attended at least one intervention session and had sufficient time to finish, 17,252 (53%) completed: intention-to-treat analyses demonstrated a mean weight loss of 2.3 kg (95% CI 2.2, 2.3) and an HbA1c reduction of 1.26 mmol/mol (1.20, 1.31) (0.12% [0.11, 0.12]); completer analysis demonstrated a mean weight loss of 3.3 kg (3.2, 3.4) and an HbA1c reduction of 2.04 mmol/mol (1.96, 2.12) (0.19% [0.18, 0.19]). Younger age, female sex, Asian and black ethnicity, lower socioeconomic status, and normal baseline BMI were associated with less weight loss. Older age, female sex, black ethnicity, lower socioeconomic status, and baseline overweight and obesity were associated with a smaller HbA1c reduction. CONCLUSIONS: Reductions in weight and HbA1c compare favorably with those reported in recent meta-analyses of pragmatic studies and suggest likely future reductions in participant type 2 diabetes incidence.
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Traditional methods such as the Diabetes Prevention Program rely on periodic clinical visits, one-on-one coaching, and self-reported data.
“Traditional methods such as the widely used Diabetes Prevention Program (DPP) often rely on periodic clinical visits, one-on-one coaching, and self-reported data9.”
From Impact of digital health interventions on glycemic control and weight management. (2025) · cites this paper as [9]
The Intervention section describes recurring face-to-face sessions over at least nine months, supporting periodic contact. But it specifies group-based sessions, not one-on-one coaching. The Data collection section says coaches measured participants’ weight and providers assessed HbA1c, rather than relying on self-reported data; neither section describes the sessions as clinical visits. Page numbers are not available in our copy. (LLM, conf=0.88)
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- Authors
- Valabhji, J., Barron, E., Bradley, D., Bakhai, C., Fagg, J., O’Neill, S., Young, B., Wareham, N., Khunti, K., Jebb, S., & Smith, J.
- Affiliations
- Imperial College Healthcare NHS Trust (GB)
- Public Health England (GB)
- NHS England (GB)
- Public Health England, London, U.K.
- Diabetes UK (GB)
- MRC Epidemiology Unit, University of Cambridge, Cambridge, U.K.
- University of Leicester (GB)
- University of Oxford (GB)
- Corresponding author
- Valabhji, Jonathan
- Venue
- Diabetes Care
- Publisher
- American Diabetes Association
- Published
- 2019-12-12
- Volume
- 43
- Issue
- 1
- Pages
- 152-160
- ISSN
- 0149-5992 (ISSN-L)
- 1935-5548
- PMC
- PMC7115827
- OpenAlex
- W2983543672
- Cited by
- 211
- References
- 19
- Citations by year
- 2026: 20 · 2025: 31 · 2024: 34 · 2023: 51 · 2022: 36 · 2021: 28 · 2020: 10
- FWCI
- 15.02
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Diabetes Care (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Apollo (University of Cambridge) (submittedVersion)
- Apollo
- Funders
- National Institute for Health and Care Research (NF-SI-0617-10064, NF-SI-0617-10080, NF-SI-0617-10149)
- Medical Research Council (MC_UU_12015/1, MR/J000515/1)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
- Keywords
- diabetes prevention programmes, prediabetes, weight loss, HbA1c reduction, intervention attendance, socioeconomic status, ethnicity, baseline BMI, type 2 diabetes prevention
- MeSH terms
- Adult, Aged, Aged, 80 and over, Diabetes Mellitus, Type 2, England, Female, Humans, Hyperglycemia, Male, Middle Aged, Obesity, Prediabetic State, Preventive Health Services, Preventive Medicine, State Medicine, Weight Loss, Outcome Assessment, Health Care, Weight Reduction Programs
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