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The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.

The Rise of Childhood Type 1 Diabetes in the 20th Century

Open access
Gale, Edwin A.M.·2002·Diabetes

Abstract

The incidence of childhood type 1 diabetes increased worldwide in the closing decades of the 20th century, but the origins of this increase are poorly documented. A search through the early literature revealed a number of useful but neglected sources, particularly in Scandinavia. While these do not meet the exacting standards of more recent surveys, tentative conclusions can be drawn concerning long-term changes in the demography of the disease. Childhood type 1 diabetes was rare but well recognized before the introduction of insulin. Low incidence and prevalence rates were recorded in several countries over the period 1920–1950, and one carefully performed study showed no change in childhood incidence over the period 1925–1955. An almost simultaneous upturn was documented in several countries around the mid-century. The overall pattern since then is one of linear increase, with evidence of a plateau in some high-incidence populations and of a catch-up phenomenon in some low-incidence areas. Steep rises in the age-group under 5 years have been recorded recently. The disease process underlying type 1 diabetes has changed over time and continues to evolve. Understanding why and how this produced the pandemic of childhood diabetes would be an important step toward reversing it.

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Metadata

Authors
Gale, E. A. M.
Venue
Diabetes
Published
2002-12-01
Volume
51
Issue
12
Pages
3353-3361
ISSN
  • 0012-1797 (ISSN-L)
  • 1939-327X
OpenAlex
W2155766648
Cited by
624
References
55
FWCI
10.67
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: The Rise of Childhood Type 1 Diabetes in the 20th Century. https://app.cochat.ai/papers/10.2337/diabetes.51.12.3353
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Gale, E. A. M. (2002). The Rise of Childhood Type 1 Diabetes in the 20th Century. Diabetes. https://doi.org/10.2337/diabetes.51.12.3353

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