Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of a Single-Dose of NN2211, a Long-Acting Glucagon-Like Peptide 1 Derivative, in Healthy Male Subjects
Elbrønd, Bodil, Jakobsen, Grethe, Larsen, Søren, Agersø, Henrik, Jensen, Lisbeth Bjerring, Rolan, Paul, Sturis, Jeppe, Hatorp, Vibeke +1 more·2002·Diabetes Care
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- Incretin agents in type 2 diabetes.Stuart A. Ross, Jean-Marie Ékoé · 2010 · PubMed Central
- Population Pharmacokinetics of Liraglutide, a Once‐Daily Human Glucagon‐Like Peptide‐1 Analog, in Healthy Volunteers and Subjects With Type 2 Diabetes, and Comparison to Twice‐Daily ExenatideEstelle Watson, Daniël Martijn Jonker, Lisbeth Vestergård Jacobsen, Steen H. Ingwersen · 2010 · The Journal of Clinical Pharmacology
- Overview of glucagon-like peptide-1 analogs and dipeptidyl peptidase-4 inhibitors for type 2 diabetes.Richard E. Pratley · 2008 · PubMed Central
- Incretin mimetics: a novel therapeutic option for patients with type 2 diabetes – a reviewFilip Krag Knop, Katrine Bagge Hansen, Filip Krag Knop · 2010 · Diabetes Metabolic Syndrome and Obesity
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- Selection and Dosing of Medications for Management of Diabetes in Patients with Advanced Kidney DiseaseJames B. Reilly, Jeffrey S. Berns · 2010 · Seminars in Dialysis
- Once-Weekly GLP-1 Agonists: How Do They Differ from Exenatide and Liraglutide?Mikkel Christensen, Filip Krag Knop · 2010 · Current Diabetes Reports
- Dual-acting peptide with prolonged glucagon-like peptide-1 receptor agonist and glucagon receptor antagonist activity for the treatment of type 2 diabetesThomas H. Claus, Clark Q. Pan, Joanne M. Buxton, Ling Yang, Jennifer C Reynolds, Nicole Barucci, Michael G. Burns, Astrid A. Ortiz, Steve Roczniak, James N. Livingston et al. · 2007 · Journal of Endocrinology
- Novel Pharmacologic Agents for Type 2 DiabetesGabriel Ikponmosa Uwaifo, Robert E. Ratner · 2005 · Endocrinology and Metabolism Clinics of North America
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- Review of the Therapeutic Uses of LiraglutideGina J. Ryan, Karla T. Foster, Lynetta M. Johnson · 2011 · Clinical Therapeutics
- A Possible Role of GLP-1 in the Pathophysiology of Early Dumping SyndromeYamamoto, Hiroshi, Mori, Tsuyoshi, Tsuchihashi, Hiroshi, Akabori, Hiroya, Naito, Hiroyuki, Tani, Tohru · 2005 · Digestive Diseases and Sciences
- LiraglutideCaroline M. Perry · 2011 · Drugs
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- Cardiovascular safety and benefits of GLP-1 receptor agonistsNiels B. Dalsgaard, Andreas Brønden, Tina Vilsbøll, Filip Krag Knop · 2017 · Expert Opinion on Drug Safety
- Lixisenatide, a novel GLP ‐1 receptor agonist: efficacy, safety and clinical implications for type 2 diabetes mellitusGeremia B. Bolli, David R. Owens · 2013 · Diabetes Obesity and Metabolism
- The effect of the once-daily human glucagon-like peptide 1 analog liraglutide on the pharmacokinetics of acetaminophenKapitza, Christoph, Zdravkovic, Milan, Hindsberger, Charlotte, Flint, Anne · 2011 · Advances in Therapy
- Comparative effectiveness of liraglutide in the treatment of type 2 diabetesGian Paolo Fadini, Mauro Rigato · 2014 · Diabetes Metabolic Syndrome and Obesity
- Preparation and characterization of a novel exendin‐4 human serum albumin fusion protein expressed in Pichia pastorisYan‐Shan Huang, Zhi Chen, Yi‐Qiong Chen, Guo‐Chang MA, Jian‐Feng Shan, Wei Liu, Linfu Zhou · 2007 · Journal of Peptide Science
- Pharmacokinetic and pharmacodynamic evaluation of site-specific PEGylated glucagon-like peptide-1 analogs as flexible postprandial-glucose controllersSu Young Chae, Young Goo Chun, Seulki Lee, Cheng‐Hao Jin, Eun Seong Lee, Kang Choon Lee, Yu Seok Youn · 2008 · Journal of Pharmaceutical Sciences
- An association between liraglutide treatment and reduction in excessive daytime sleepiness in obese subjects with type 2 diabetesFernando Gómez Peralta, Cristina Abreu, Jose Carlos Castro, Elvira Alcarria, Margarita Cruz-Bravo, Maria Jesús Garcia-Llorente, Cristina Albornos, Concepción Moreno, María Cepeda, Francisca Almodóvar · 2015 · BMC Endocrine Disorders
- Focus on therapeutic peptides and their deliveryElise Rosson, François Lux, Laurent David, Yann Godfrin, Olivier Tillement, Eloïse Thomas · 2025 · International Journal of Pharmaceutics
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- Discovery of Tarantula Venom-Derived NaV1.7-Inhibitory JzTx-V Peptide 5-Br-Trp24 Analogue AM-6120 with Systemic Block of Histamine-Induced PruritisBin Wu, Justin K. Murray, Kristin L. Andrews, Kelvin K. C. Sham, Jason Long, Jennifer Aral, Joseph Ligutti, Shanti M. Amagasu, Dong Liu, Anruo Zou et al. · 2018 · Journal of Medicinal Chemistry
- Glucagon-Like Peptide-1 Receptor Agonist Treatment Attributes Important to Injection-Experienced Patients with Type 2 Diabetes Mellitus: A Preference Study in Germany and the United KingdomLei Qin, Stephanie Chen, Emuella M. Flood, Alka Shaunik, Beverly Romero, Marie de la Cruz, Cynthia Alvarez, Susan Grandy · 2017 · Diabetes Therapy
- Liraglutide Therapy for Type 2 Diabetes: Overcoming Unmet NeedsÅke Sjöholm · 2010 · Pharmaceuticals
- DsAAV8-mediated expression of glucagon-like peptide-1 in pancreatic beta-cells ameliorates streptozotocin-induced diabetesMichael J Riedel, Daniel F. Gaddy, Ali Asadi, Paul D. Robbins, Timothy J. Kieffer · 2009 · Gene Therapy
- A GLP‐1 receptor agonist conjugated to an albumin‐binding domain for extended half‐lifeJoel Lindgren, Essam Refai, Sergei V Zaitsev, Lars Abrahmsén, Per‐Olof Berggren, Amelie Eriksson Karlström · 2014 · Biopolymers
- Glucagon-like peptide 1 (GLP-1) and metabolic diseasesCarlo Maria Rotella, Laura Pala, Edoardo Mannucci · 2005 · Journal of Endocrinological Investigation
- GLP-1 Receptor Agonists Induce Growth Hormone Secretion in Healthy VolunteersHeinla, Keiu, Vasar, Eero, Reppo, Ingrid, Sedman, Tuuli, Volke, Vallo · 2023 · Diabetes Therapy
- Pharmacokinetics and Pharmacodynamics of Liraglutide, a Long‐Acting, Potent Glucagon‐Like Peptide‐1 AnalogJerry D. Meece · 2009 · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
- Investigational treatments for Type 2 diabetes mellitus: exenatide and liraglutideClaudio Daniel González, Valeria Beruto, Guillermo Alberto Keller, Silvina Santoro, Guillermo Di Girolamo · 2006 · Expert Opinion on Investigational Drugs
- Pharmacotherapy of Diabetes: New DevelopmentsCarl Erik Mogensen · 2007 · Springer eBooks
- Strategies to Optimize Peptide Stability and Prolong Half-LifeSophia M. Shi, Li Di · 2022 · AAPS advances in the pharmaceutical sciences series
- Pharmacology, efficacy and safety of liraglutide in the management of type 2 diabetesR. Keith Campbell, Joshua J. Neumiller · 2010 · Diabetes Metabolic Syndrome and Obesity
- Gut peptides in the treatment of diabetes mellitusTorsten Peter Vahl, David A. D’Alessio · 2004 · Expert Opinion on Investigational Drugs
- The Pharmacokinetics, Pharmacodynamics, and Tolerability of Liraglutide, a Once-Daily Human GLP-1 Analogue, After Multiple Subcutaneous Administration in Healthy Chinese Male SubjectsJi Jiang, Jianyan Zhang, Lisbeth Vestergård Jacobsen, Pei Hu · 2011 · The Journal of Clinical Pharmacology
- IDegLira Improves Both Fasting and Postprandial Glucose Control as Demonstrated Using Continuous Glucose Monitoring and a Standardized Meal TestJens Juul Holst, John B. Buse, Helena W. Rodbard, Sultan Linjawi, Vincent C. Woo, Trine Welløv Boesgaard, Kajsa Kvist, Stephen C. L. Gough · 2015 · Journal of Diabetes Science and Technology
- Unravelling Polycystic Ovary Syndrome and Its ComorbiditiesKyung-Wook Kim · 2021 · Journal of Obesity & Metabolic Syndrome
- Preserved pharmacokinetic exposure and distinct glycemic effects of insulin degludec and liraglutide in IDegLira, a fixed‐ratio combination therapyChristoph Kapitza, Bruce W. Bode, Steen H. Ingwersen, Lisbeth Vestergård Jacobsen, Pernille Poulsen · 2015 · The Journal of Clinical Pharmacology
- Novel therapeutic agents for the treatment of diabetic kidney diseaseRachel E. Hartman, Shantanu Rao, Mariann D. Churchwell, Susan J. Lewis · 2020 · Expert Opinion on Investigational Drugs
- Vascular Complications of Diabetes MellitusYien Chiong, Carmella Evans‐Molina · 2014 · Springer eBooks
- Cardiovascular Effects of Incretin-Based TherapiesWilliam B. White, William L. Baker · 2016 · Annual Review of Medicine
- The efficacy and safety of liraglutide added to metformin in patients with diabetes: a meta-analysis of randomized controlled trialsJianqiu Gu, Meng Xin, Yan Ping Guo, Lei Wang, Hongzhi Zheng, Yixuan Liu, Bingshu Wu, Difei Wang · 2016 · Scientific Reports
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- Newer therapeutic options for children with diabetes mellitus: theoretical and practical considerationsGeorge S. Jeha, Rubina A. Heptulla · 2006 · Pediatric Diabetes
- Octreotide improves early dumping syndrome potentially through incretins: a case reportDaisuke Sato, Katsutaro Morino, Natsuko Ohashi, Emi Ueda, Kazuhiro Ikeda, Hideka Yamamoto, Satoshi Ugi, Hiroshi Yamamoto, Shin‐ichi Araki, Hiroshi Maegawa · 2013 · Endocrine Journal
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- Liraglutide in Adults with Type 2 Diabetes: Global Perspective on Safety, Efficacy and Patient PreferenceDaisuke Yabe, Yutaka Seino · 2011 · Clinical Medicine Insights Endocrinology and Diabetes
- Laparoscopic adjustable gastric banding with liraglutide in adults with obesity and type 2 diabetes (GLIDE): a pilot randomised placebo controlled trialCláudia Matta-Coelho, Laurence J. Dobbie, James Crane, Abdel Douiri, Annastazia Learoyd, Olanike Okolo, Spyros Panagiotopoulos, Dimitri J. Pournaras, Sasindran Ramar, Francesco Rubino et al. · 2023 · International Journal of Obesity
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- Combining Basal Insulin Analogs with Glucagon-Like Peptide-1 MimeticsRiccardo Perfetti · 2011 · Diabetes Technology & Therapeutics
- Rational Design by Structural Biology of Industrializable, Long-Acting Antihyperglycemic GLP-1 Receptor AgonistsSun, Lei, Zheng, Zhi-Ming, Shao, Chang-Sheng, Zhang, Zhi-Yong, Li, Ming-Wei, Wang, Li, Wang, Han, Zhao, Gen-Hai, Wang, Peng · 2022 · Pharmaceuticals
- Microneedle patch with pure drug tips for delivery of liraglutide: pharmacokinetics in rats and minipigsHongbing Lin, Jinbin Liu, Yulin Hou, Zhiyan Yu, Juan Hong, Jianghong Yu, Yu Chen, Jingwen Hu, Dengning Xia · 2024 · Drug Delivery and Translational Research
- Effect of Three Different Injection Sites on the Pharmacokinetics of the Once-Daily Human GLP-1 Analogue LiraglutideChristoph Kapitza, Milan Zdravkovic, Eric Zijlstra, Stine Segel, Tim Heise, Anne Flint · 2010 · The Journal of Clinical Pharmacology
- Adapting the GLP-1-Signaling System to the Treatment of Type 2 DiabetesTeresa Salvatore, Ornella Carbonara, Domenico Cozzolino, Roberto Torella, Ferdinando Carlo Sasso · 2007 · Current Diabetes Reviews
- Comparative Assessment of Lixisenatide, Exenatide, and Liraglutide Pen DevicesUdo Stauder, Diplom Enginee, Hina Elton, Alfred Penfornis, Steven V. Edelman · 2014 · Journal of Diabetes Science and Technology
- Opportunities of Antidiabetic Drugs in Cardiovascular MedicineCen Yan, Lutgarde Thijs, Yu Cao, Sander Trenson, Zhen‐Yu Zhang, Stefan P. Janssens, Jan Albert Staessen, Yingmei Feng · 2020 · Hypertension
- Obesity‐related genes are expressed in human Sertoli cells and modulated by energy homeostasis regulating hormonesSara Pereira, Ana Dias Martins, Bruno P. Moreira, Raquel L. Bernardino, Alberto Barros, Mariana Pereira Monteiro, Pedro Fontes Oliveira, Marco Gouveia Alves · 2020 · Journal of Cellular Physiology
- Optimization of pig models for translation of subcutaneous pharmacokinetics of therapeutic proteins: Liraglutide, insulin aspart and insulin detemirKaren‐Margrethe Pedersen, Anna Katrina Jógvansdóttir Gradel, Trine Pagh Ludvigsen, Berit Østergaard Christoffersen, Caroline Amalie Fuglsang-Damgaard, Kristian Moss Bendtsen, Suzi Høgh Madsen, Valentina Manfé, Hanne H. F. Refsgaard · 2021 · Translational research
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- Liraglutide: A once-daily human glucagon-like peptide-1 analogue for type 2 diabetes mellitusDavid Joffe · 2010 · American Journal of Health-System Pharmacy
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