Cited by 924Diabetes Management and ResearchDiabetes and associated disordersDiabetes, Cardiovascular Risks, and Lipoproteins

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index; 1 of the 49 sources its claims cite were checked for support.

Diagnosis and Classification of Diabetes Mellitus

Open access
American Diabetes Association·2006·Diabetes Care

Abstract

MELLITUS -Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both.The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction, and failure of various organs, especially the eyes, kidneys, nerves, heart, and blood vessels.Several pathogenic processes are involved in the development of diabetes.These range from autoimmune destruction of the ␤-cells of the pancreas with consequent insulin deficiency to abnormalities that result in resistance to insulin action.The basis of the abnormalities in carbohydrate, fat, and protein metabolism in diabetes is deficient action of insulin on target tissues.Deficient insulin action results from inadequate insulin secretion and/or diminished tissue responses to insulin at one or more points in the complex pathways of hormone action.Impairment of insulin secretion and defects in insulin action frequently coexist in the same patient, and it is often unclear which abnormality, if either alone, is the primary cause of the hyperglycemia.Symptoms of marked hyperglycemia include polyuria, polydipsia, weight loss, sometimes with polyphagia, and blurred vision.Impairment of growth and susceptibility to certain infections may also accompany chronic hyperglycemia.Acute, life-threatening consequences of uncontrolled diabetes are hyperglycemia with ketoacidosis or the nonketotic hyperosmolar syndrome.Long-term complications of diabetes include retinopathy with potential loss of vision; nephropathy leading to renal failure; peripheral neuropathy with risk of foot ulcers, amputations, and Charcot joints; and autonomic neuropathy causing gastrointes-

Overview

Integrity signals

Registry

Crossref · 10.2337/diacare.29.s1.06.s43

Cites

4 of 4 references verified0 citation errors · 0 not checkable

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Nothing to recompute.

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Claims the paper makes

47 Not checked yet · 4 Own interpretation · 1 Couldn’t confirm · 1 Own method · accuracy not yet measured

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Show all 23 claims

  • Probably not a substantial claim. 17
  • It may state two separate claims as one. 21
30 of 30
  • The authors state this as an assumption.

    In insulin-resistant lipoatrophic diabetes, the lesion responsible resides in the postreceptor signal transduction pathways.

    “Therefore, it is assumed that the lesion(s) must reside in the postreceptor signal transduction pathways.”
  • The paper relies on this without support.

    Glucose tolerance normally deteriorates during pregnancy, especially in the third trimester.

    “Deterioration of glucose tolerance occurs normally during pregnancy, particularly in the 3rd trimester.”
2 of 2

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2 of 2

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Items 701–800 of 924

Metadata

Authors
American Diabetes Association
Corresponding author
American Diabetes Association
Venue
Diabetes Care
Published
2006-01-01
Volume
29
Issue
suppl_1
Pages
s43-s48
ISSN
  • 0149-5992 (ISSN-L)
  • 1935-5548
OpenAlex
W4205321574
Cited by
924
References
4
Citations by year
2026: 11 · 2025: 12 · 2024: 17 · 2023: 30 · 2022: 45 · 2021: 32 · 2020: 34 · 2019: 21 · 2018: 47 · 2017: 44 · 2016: 27 · 2015: 43 · 2014: 57 · 2013: 43 · 2012: 44
FWCI
65.40
Type
journal article
Language
en
Open access
Locations
Diabetes Care (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
diabetes mellitus, diagnosis, classification, hyperglycemia, insulin secretion, insulin resistance, islet autoimmunity, diabetes complications, diabetic ketoacidosis, retinopathy, kidney disease, peripheral neuropathy, autonomic neuropathy

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