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Differences in the skin surface pH and bacterial microflora due to the long-term application of synthetic detergent preparations of pH 5.5 and pH 7.0. Results of a crossover trial in healthy volunteers.
Open accessAbstract
Skin cleansing preparations consisting of identical synthetic detergents but differing in pH-value (pH 5.5 and 7.0) were applied twice daily on the forehead and forearm of healthy volunteers in a randomized crossover trial. The skin surface pH was found to be significantly higher when the neutral preparation had been used, as was the propionibacterial count (p less than 0.05). The number of propionibacteria was significantly linked to the skin pH. Hence even minor differences in the pH of skin cleansing preparations seem to be of importance for the integrity of the skin surface. This should be taken into account when planning the formulation of optimal skin care products.
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Citations
Cited by
Grice, E. A., & Segre, J. A. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2537 · Cited by 3,143
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Elias, P. M. (2005) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2005.23668.x · Cited by 772
Skin pH: from basic science to basic skin care
Ali, S., & Yosipovitch, G. (2013) · Acta Dermato Venereologica · doi:10.2340/00015555-1531 · Cited by 690
Hachem, J.-P., Man, M.-Q., Crumrine, D., Uchida, Y., Brown, B. E., Rogiers, V., Roseeuw, D., Feingold, K. R., & Elias, P. M. (2005) · Journal of Investigative Dermatology · doi:10.1111/j.0022-202x.2005.23838.x · Cited by 314
The impact of the pH value on skin integrity and cutaneous wound healing
Schreml, S., Szeimies, R., Karrer, S., Heinlin, J., Landthaler, M., & Babilas, P. (2010) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/j.1468-3083.2009.03413.x · Cited by 279
Metadata
- Authors
- Korting, H. C., Hübner, K., Greiner, K., Hamm, G., & Braun-Falco, O.
- Venue
- Acta Dermato-Venereologica
- Publisher
- Medical Journals Sweden AB
- Published
- 1990-09-01
- Volume
- 70
- Issue
- 5
- Pages
- 429-431
- ISSN
- 0001-5555 (ISSN-L)
- 1651-2057
- OpenAlex
- W2399619504
- Cited by
- 171
- References
- 0
- FWCI
- 1.95
- Type
- journal article
- Language
- en
- Open access
- gold
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- CoChat. (2026). Citation check: Differences in the skin surface pH and bacterial microflora due to the long-term application of synthetic detergent preparations of pH 5.5 and pH 7.0. Results of a crossover trial in healthy volunteers. https://app.cochat.ai/papers/10.2340/0001555570429431
- The paper
- Korting, H. C., Hübner, K., Greiner, K., Hamm, G., & Braun-Falco, O. (1990). Differences in the skin surface pH and bacterial microflora due to the long-term application of synthetic detergent preparations of pH 5.5 and pH 7.0. Results of a crossover trial in healthy volunteers. Acta Dermato-Venereologica. https://doi.org/10.2340/0001555570429431
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
