BAG3 Deficiency Results in Fulminant Myopathy and Early Lethality

Cited by (243)

Items 101–200 of 243

1. Familial Dilated Cardiomyopathy Caused by a Novel Frameshift in the BAG3 Gene
   Rocío Toro, Alexandra Pérez‐Serra, Óscar Campuzano, Javier Moncayo, Catarina Allegue, Anna Iglesias, Alipio Mangas, Ramón Brugada · 2016 · PLoS ONE
2. Metformin rescues muscle function in BAG3 myofibrillar myopathy models
   Avnika Ashok Ruparelia, Emily A. McKaige, Caitlin Williams, Keith E. Schulze, Margit Fuchs, Viola M. J. Oorschot, Emmanuelle Lacène, Mirella Meregalli, Clara Lee, Rita J. Serrano et al. · 2020 · Autophagy
3. Neuromuscular Disease Models and Analysis
   Robert W. Burgess, Gregory A. Cox, Kevin L. Seburn · 2009 · Methods in molecular biology
4. BAG3 protein regulates caspase‐3 activation in HIV‐1‐infected human primary microglial cells
   Alessandra Rosati, Kamel Khalili, Satish L. Deshmane, Sujatha Radhakrishnan, Maria Carmela Pascale, Maria Caterina Turco, Liberato Marzullo · 2008 · Journal of Cellular Physiology
5. Myoblast mechanotransduction and myotube morphology is dependent on BAG3 regulation of YAP and TAZ
   Kemal Arda Günay, Jason S. Silver, Tze-Ling Chang, Olivia J. Bednarski, Kendra L. Bannister, Cameron J. Rogowski, Bradley B. Olwin, Kristi S. Anseth · 2021 · Biomaterials
6. Advances in the role and mechanism of BAG3 in dilated cardiomyopathy
   Leiling Liu, Kaijun Sun, Xiaojun Zhang, Ying Tang, Danyan Xu · 2019 · Heart Failure Reviews
7. Myocardial Inflammation as a Manifestation of Genetic Cardiomyopathies: From Bedside to the Bench
   Peretto, Giovanni, Sommariva, Elena, Di Resta, Chiara, Rabino, Martina, Villatore, Andrea, Lazzeroni, Davide, Sala, Simone, Pompilio, Giulio, Cooper, Leslie T. · 2023 · Biomolecules
8. Disrupted autophagy undermines skeletal muscle adaptation and integrity
   Elliot J. Jokl, Gonzalo Blanco · 2016 · Mammalian Genome
9. Mutations in BAG3 cause adult-onset Charcot-Marie-Tooth disease
   Michael E. Shy, Adriana P. Rebelo, Shawna M. E. Feely, Lisa Abreu, Feifei Tao, Andrea Swenson, Chelsea J. Bacon, Stephan L. Zuchner · 2017 · Journal of Neurology Neurosurgery & Psychiatry
10. Haplo‐insufficiency of Bcl2‐associated athanogene 3 in mice results in progressive left ventricular dysfunction, β‐adrenergic insensitivity, and increased apoptosis
    Valerie D. Myers, Dhanendra Tomar, Muniswamy Madesh, JuFang Wang, Jianliang Song, Xue-Qian Zhang, Manish Kumar Gupta, Farzaneh G. Tahrir, Jennifer Gordon, Joseph M. McClung et al. · 2018 · Journal of Cellular Physiology
11. Getting Folded: Chaperone Proteins in Muscle Development, Maintenance and Disease
    Daniel A. Smith, Carmen Rivero Carland, Yiming Guo, Sanford I. Bernstein · 2014 · The Anatomical Record
12. Bis deficiency results in early lethality with metabolic deterioration and involution of spleen and thymus
    Dong‐Ye Youn, Dong-Hyoung Lee, Mi-Hyun Lim, Jung‐Sook Yoon, Ji Hee Lim, Seung Eun Jung, Chung Eun Yeum, Cheol Whee Park, Ho‐Joong Youn, Jae‐Seon Lee et al. · 2008 · American Journal of Physiology-Endocrinology and Metabolism
13. Understanding the molecular basis of cardiomyopathy
    Marie‐Louise Bang, Julius Bogomolovas, Ju Chen · 2021 · American Journal of Physiology-Heart and Circulatory Physiology
14. Chaperones and the Proteasome System: Regulating the Construction and Demolition of Striated Muscle
    Casey Carlisle, Kendal Prill, David B. Pilgrim · 2017 · International Journal of Molecular Sciences
15. Assembly and Maintenance of Sarcomere Thin Filaments and Associated Diseases
    Kendal Prill, John Dawson · 2020 · International Journal of Molecular Sciences
16. Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy
    Kenichi Kimura, Astrid Ooms, Kathrin Graf-Riesen, Maithreyan Kuppusamy, Andreas Unger, Julia Schuld, Jan Daerr, Achim Lother, Caroline Geisen, Lutz Hein et al. · 2021 · Nature Communications
17. The BAG3-dependent and -independent roles of cardiac small heat shock proteins
    Xi Fang, Julius Bogomolovas, Christa L. Trexler, Ju Chen · 2019 · JCI Insight
18. Genetic compensation prevents myopathy and heart failure in an in vivo model of Bag3 deficiency
    Federica Diofano, Karolina Weinmann, Isabelle Schneider, Kevin D. Thiessen, Wolfgang Rottbauer, Steffen Just · 2020 · PLoS Genetics
19. Myofibrillar myopathies
    Duygu Selcen · 2010 · Current Opinion in Neurology
20. Gene expression profiling of porcine skeletal muscle in the early recovery phase following acute physical activity
    Jeanette H. Jensen, Lene Nagstrup Conley, Jakob Hedegaard, Mathilde Nielsen, J.F. Young, Niels Oksbjerg, Henrik Hornshøj, Christian Bendixen, Bo Thomsen · 2012 · Experimental Physiology
21. BAG3 Proteomic Signature under Proteostasis Stress
    Christof Hiebel, Elisabeth Stürner, Meike Hoffmeister, Georg Tascher, Mario Schwarz, Heike Nagel, Christian Behrends, Christian Münch, Christian Behl · 2020 · Cells
22. Role of BAG3 protein in leukemia cell survival and response to therapy
    Alessandra Rosati, Anna Maria Basile, Antonia Falco, Morena d’Avenia, Michelina Festa, Vincenzo Graziano, Vincenzo De Laurenzi, Claudio Arra, Maria Carmela Pascale, Maria Caterina Turco · 2012 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
23. Co‐chaperone BAG3 and adenovirus penton base protein partnership
    Evelyne Gout, Małgorzata Gutkowska, Shin-ichi Joseph Takayama, John C. Reed, Jadwiga Chroboczek · 2010 · Journal of Cellular Biochemistry
24. The Hippo network kinase STK38 contributes to protein homeostasis by inhibiting BAG3-mediated autophagy
    Christina Klimek, Ricarda Jahnke, Judith Wördehoff, Barbara Kathage, Daniela Stadel, Christian Behrends, Alexander Hergovich, Jörg Höhfeld · 2019 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
25. Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy
    Rocío Bengoechea, Andrew R. Findlay, Ankan Kumar Bhadra, Hao Shao, Kevin C. Stein, Sara K. Pittman, Jil Daw, Jason E. Gestwicki, Heather L. True, Conrad Chris Weihl · 2020 · Journal of Clinical Investigation
26. Cardiac Dysfunction in HIV‐1 Transgenic Mouse: Role of Stress and BAG3
    Joseph Y. Cheung, Jennifer Gordon, JuFang Wang, Jianliang Song, Xue-Qian Zhang, Douglas G. Tilley, Erhe Gao, Walter J. Koch, Joseph E. Rabinowitz, Paul E. Klotman et al. · 2015 · Clinical and Translational Science
27. The Anti-Apoptotic Activity of BAG3 Is Restricted by Caspases and the Proteasome
    Victoria M. Virador, Ben Davidson, Josephine A. Czechowicz, Alisha Mai, Jareer N. Kassis, Elise C. Kohn · 2009 · PLoS ONE
28. BAG3 plays a central role in proteostasis in the heart
    Wataru Mizushima, Junichi Sadoshima · 2017 · Journal of Clinical Investigation
29. Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish
    Yonghe Ding, Alexey V. Dvornikov, Xiao Ma, Hong Zhang, Yong Wang, Matthew R. Lowerison, René R. Sevag Packard, Lei Wang, Jun Chen, Yuji Zhang et al. · 2019 · Disease Models & Mechanisms
30. Microarray analysis after strenuous exercise in peripheral blood mononuclear cells of endurance horses
    Stefano Capomaccio, Katia Cappelli, Éric Barrey, Michela Felicetti, Maurizio Silvestrelli, A. Verini‐Supplizi · 2010 · Animal Genetics
31. Exome sequencing identifies variants in two genes encoding the LIM-proteins NRAP and FHL1 in an Italian patient with BAG3 myofibrillar myopathy
    Francesca D’Avila, Mirella Meregalli, Sara Lupoli, Matteo Barcella, Alessandro Orro, Francesca De Santis, Clementina Sitzia, Andrea Farini, Pasqualina D’Ursi, Silvia Erratico et al. · 2016 · Journal of Muscle Research and Cell Motility
32. Diabetes Upregulates Oxidative Stress and Downregulates Cardiac Protection to Exacerbate Myocardial Ischemia/Reperfusion Injury in Rats
    Chen-Yen Chien, Ting-Jui Wen, Yu-Hsiuan Cheng, Yi-Ting Tsai, Chih-Yao Chiang, Chih-Yao Chiang · 2020 · Antioxidants
33. Heat Shock Proteins: Important Helpers for the Development, Maintenance and Regeneration of Skeletal Muscles
    Silvia Pomella, Matteo Cassandri, Francesco Antoniani, Samuele Crotti, Laura Mediani, Beatrice Silvestri, Margherita Medici, Rossella Rota, Alessandro Rosa, Serena Carra · 2023 · Muscles
34. Locus specific epigenetic modalities of random allelic expression imbalance
    Lucile Marion‐Poll, Benjamin Forêt, Dina Zielinski, Florian Massip, Mikaël Attia, Ava C. Carter, Laurène Syx, Howard Y. Chang, Anne-Valérie Gendrel, Édith Heard · 2021 · Nature Communications
35. Molecular Signaling to Preserve Mitochondrial Integrity against Ischemic Stress in the Heart: Rescue or Remove Mitochondria in Danger
    Justin D. Yu, Shigeki Miyamoto · 2021 · Cells
36. BAG3: Nature’s Quintessential Multi-Functional Protein Functions as a Ubiquitous Intra-Cellular Glue
    Caitlyn Brenner, Muaaz Choudhary, Michael G. McCormick, David Cheung, Gavin P. Landesberg, Jufang Wang, Jianliang Song, Thomas G. Martin, Joseph Y. Cheung, Hui‐Qi Qu et al. · 2023 · Cells
37. Animal Models of Congenital Cardiomyopathies Associated With Mutations in Z-Line Proteins
    Marie‐Louise Bang · 2016 · Journal of Cellular Physiology
38. Cardiac fibroblast BAG3 regulates TGFBR2 signaling and fibrosis in dilated cardiomyopathy
    Bryan Z. Wang, Margaretha A. J. Morsink, Seong Won Kim, Lori J. Luo, Xiaokan Zhang, Rajesh Kumar Soni, Roberta I. Lock, Jenny Rao, Youngbin Kim, Anran Zhang et al. · 2025 · Journal of Clinical Investigation
39. P209L mutation in Bag3 does not cause cardiomyopathy in mice
    Xi Fang, Julius Bogomolovas, Paul Shichao Zhou, Yongxin Mu, Xiaolong Ma, Ze’e Chen, Lunfeng Zhang, Mason Zhu, Jennifer Veevers, Kunfu Ouyang et al. · 2018 · American Journal of Physiology-Heart and Circulatory Physiology
40. BAG3 expression and sarcomere localization in the human heart are linked to HSF-1 and are differentially affected by sex and disease
    Thomas G. Martin, Sara Tawfik, Christine Schomisch Moravec, Toni R. Pak, Jonathan A. Kirk · 2021 · American Journal of Physiology-Heart and Circulatory Physiology
41. Multivalent protein–protein interactions are pivotal regulators of eukaryotic Hsp70 complexes
    Oleta T. Johnson, Jason E. Gestwicki · 2022 · Cell Stress and Chaperones
42. Therapeutic induction of Bcl2‐associated athanogene 3‐mediated autophagy in idiopathic pulmonary fibrosis
    Shashi Chillappagari, Julian Schwarz, Vidyasagar Kesireddy, J. Knöll, Martina Korfei, Konrad Höetzenecker, Michael Lienhard Schmitz, Christian Behl, Savério Bellusci, Andreas Günther et al. · 2022 · Clinical and Translational Medicine
43. The Genetic Evaluation of Dilated Cardiomyopathy
    Quan M. Bui, Jeffrey Ding, Kimberly N. Hong, Eric A. Adler · 2023 · Structural Heart
44. Regulation of Hspb7 by MEF2 and AP-1: implications for Hspb7 in muscle atrophy
    Stephanie Wales Tobin, Dabo Yang, John Girgis, Ali Farahzad, Alexandre Blais, John C. McDermott · 2016 · Journal of Cell Science
45. Nucleotide Exchange Factors for Hsp70 Molecular Chaperones: GrpE, Hsp110/Grp170, HspBP1/Sil1, and BAG Domain Proteins.
    A. Bracher, J. Verghese · 2023 · Sub-cellular biochemistry
46. Bag3 Regulates Mitochondrial Function and the Inflammasome Through Canonical and Noncanonical Pathways in the Heart
    JuFang Wang, Dhanendra Tomar, Thomas G. Martin, Shubham Dubey, Praveen Kumar Dubey, Jianliang Song, Gavin P. Landesberg, Michael G. McCormick, Valerie D. Myers, Salim Merali et al. · 2023 · JACC Basic to Translational Science
47. Development of an anti‐BAG3 humanized antibody for treatment of pancreatic cancer
    Anna Maria Basile, Margot De Marco, Michelina Festa, Antonia Falco, Vittoria Iorio, Luana Guerriero, Daniela Eletto, Domenica Rea, Claudio Arra, Alessia Lamolinara et al. · 2019 · Molecular Oncology
48. Analysis of BAG3 plasma concentrations in patients with acutely decompensated heart failure
    Parul U. Gandhi, Hanna Kim Gaggin, Arianna M. Belcher, Jamie E. Harisiades, Anna Maria Basile, Antonia Falco, Alessandra Rosati, Federico Piscione, James L. Januzzi, Maria Caterina Turco · 2015 · Clinica Chimica Acta
49. BAG3 mutation in a patient with atypical phenotypes of myofibrillar myopathy and Charcot–Marie–Tooth disease
    Seung Ju Kim, Soo Hyun Nam, Sumaira Kanwal, Da Eun Nam, Da Hye Yoo, Jong‐Hee Chae, Yeon‐Lim Suh, Ki Wha Chung, Byung‐Ok Choi · 2018 · Genes & Genomics
50. Hereditary Dilated Cardiomyopathy: Recent Advances in Genetic Diagnostics
    Hyun‐Young Park · 2016 · Korean Circulation Journal
51. Characterization of BAG3 cleavage during apoptosis of pancreatic cancer cells
    Hua‐Qin Wang, Xin Meng, Yan‐Yan Gao, Bao-Qin Liu, Xiao‐Fang Niu, Haiyan Zhang, Zhen‐Xian Du · 2010 · Journal of Cellular Physiology
52. Animal Models of Cardiovascular Complications of Pregnancy
    Zoltan Pierre Arany, Denise Hilfiker‐Kleiner, S. Ananth Karumanchi · 2022 · Circulation Research
53. BAG3 expression is sustained by FGF2 in neural progenitor cells and impacts cell proliferation
    Antonio Gentilella, Kamel Khalili · 2010 · Cell Cycle
54. Pharmacological inhibition of BAG3‐HSP70 with the proposed cancer therapeutic JG‐98 is toxic for cardiomyocytes
    Thomas G. Martin, Christine E. Delligatti, Nitha Aima Muntu, Marisa J. Stachowski, Jonathan A. Kirk · 2021 · Journal of Cellular Biochemistry
55. BAG3 increases the invasiveness of uterine corpus carcinoma cells by suppressing miR-29b and enhancing MMP2 expression
    Shutaro Habata, Masahiro Iwasaki, 明香 杉尾, MIWA SUZUKI, Masato Tamate, Seiro Satohisa, Ryoichi Tanaka, Tsuyoshi Saito · 2015 · Oncology Reports
56. Myosin heavy chain is stabilized by BCL-2 interacting cell death suppressor (BIS) in skeletal muscle
    Jin Hee Hong, Jun-Sub Park, Hyun Lee, Jaemin Jeong, Hye Hyeon Yun, Hye Yun Kim, Young‐Gyu Ko, Jeong Hwa Lee · 2016 · Experimental & Molecular Medicine
57. Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy
    Rocío Bengoechea, Andrew R. Findlay, Ankan Kumar Bhadra, Hao Shao, Kevin C. Stein, Sara K. Pittman, Jil Daw, Jason E. Gestwicki, Heather L. True, Conrad Chris Weihl · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
58. Bcl-2-associated athanogene 3 (BAG3) is an enhancer of small heat shock protein turnover via activation of autophagy in the heart
    Yui Inomata, Shouta Nagasaka, Kazuki Miyate, Yuta Goto, Chizuru Hino, Chihiro Toukairin, Rieko Higashio, Kinji Ishida, Tomoyuki Saino, Masamichi Hirose et al. · 2018 · Biochemical and Biophysical Research Communications
59. Force-induced dephosphorylation activates the cochaperone BAG3 to coordinate protein homeostasis and membrane traffic
    Judith Ottensmeyer, Alessandra Esch, Henrique Baeta, Sandro Sieger, Yamini Gupta, Maximilian F Rathmann, Andreas Jeschke, Daniel Jacko, Kirill Schaaf, Thorsten Schiffer et al. · 2024 · Current Biology
60. BAG3 promotes proliferation and migration of arterial smooth muscle cells by regulating STAT3 phosphorylation in diabetic vascular remodeling
    Xinyue Huang, Jiayan Guo, Anqi Ning, Naijin Zhang, Yingxian Sun · 2024 · Cardiovascular Diabetology
61. Different roles of BAG3 in cardiac physiological hypertrophy and pathological remodeling
    Pengyu Jia, Nan Wu, Huimin Yang, Yuxuan Guo, Xiaofan Guo, Yingxian Sun · 2021 · Translational research
62. Role of Bcl2-associated Athanogene 3 in Turnover of Gap Junction Protein, Connexin 43, in Neonatal Cardiomyocytes
    Farzaneh G. Tahrir, Manish Gupta, Valerie D. Myers, Jennifer Gordon, Joseph Y. Cheung, Arthur Michael Feldman, Kamel Khalili · 2019 · Scientific Reports
63. Implication of Bcl-2-associated athanogene 3 in fibroblast growth factor-2-mediated epithelial–mesenchymal transition in renal epithelial cells
    Feng Du, Si Li, Tian Wang, Haiyan Zhang, Detian Li, Zhen‐Xian Du, Hua‐Qin Wang · 2014 · Experimental Biology and Medicine
64. Heat Shock Proteins: Potential Modulators and Candidate Biomarkers of Peripartum Cardiomyopathy
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65. Isoform-specific functions of synaptopodin-2 variants in cytoskeleton stabilization and autophagy regulation in muscle under mechanical stress
    Keerthika Lohanadan, Sibylle Molt, Franziska Dierck, Peter F. M. van der Ven, Norbert Frey, Jörg Höhfeld, Dieter O. Fürst · 2021 · Experimental Cell Research
66. A study of FHL1, BAG3, MATR3, PTRF and TCAP in Australian muscular dystrophy patients
    Leigh B. Waddell, Jenny N. Tran, Xi Zheng, Carsten G. Bönnemann, Ying Hu, Frances J. Evesson, Monkol Lek, Susan M. Arbuckle, Min‐Xia Wang, Robert L. Smith et al. · 2011 · Neuromuscular Disorders
67. Cordyceps sinensis attenuates renal fibrosis and suppresses BAG3 induction in obstructed rat kidney.
    Feng Du, Si Li, Tian Wang, Haiyan Zhang, Zhi‐Hong Zong, Zhen‐Xian Du, Detian Li, Hua‐Qin Wang, Bo Liu, Jianing Miao et al. · 2015 · Europe PMC (PubMed Central)
68. Lamin B is a target for selective nuclear PQC by BAG3: implication for nuclear envelopathies
    Manish Gupta, Jennifer Gordon, Gregory M. Glauser, Valerie D. Myers, Arthur Michael Feldman, Joseph Y. Cheung, Kamel Khalili · 2019 · Cell Death and Disease
69. Chaperone Proteins: The Rising Players in Muscle Atrophy
    Davide Acquarone, Alessandro Bertero, Mara Brancaccio, Matteo Sorge · 2024 · Journal of Cachexia Sarcopenia and Muscle
70. The Lifeact-EGFP mouse is a translationally controlled fluorescent reporter of T cell activation
    Jorge Luis Galeano Niño, Szun S. Tay, Jacqueline L.E. Tearle, Jianling Xie, Matt Govendir, Daryan Kempe, Jessica K. Mazalo, Alexander P. Drew, Feyza Colakoglu, Sarah Kummerfeld et al. · 2020 · Journal of Cell Science
71. Identification of genes related to stress affecting thymus immune function in a chicken stress model using transcriptome analysis
    Huihui Tian, Yujie Guo, Mengxia Ding, Aru Su, Wenting Li, Yadong Tian, Kui Li, Guirong Sun, Ruirui Jiang, Ruili Han et al. · 2021 · Research in Veterinary Science
72. Inhibitors of the ubiquitin proteasome system block myofibril assembly in cardiomyocytes derived from chick embryos and human pluripotent stem cells
    Jushuo Wang, Yingli Fan, Chenyan Wang, Syamalima Dube, Bernard J. Poiesz, Dipak K. Dube, Zhen Ma, Jean M. Sanger, Joseph W. Sanger · 2021 · Cytoskeleton
73. Inhibition of autophagy prevents cardiac dysfunction at early stages of cardiomyopathy in Bag3-deficient hearts
    Giovanni Maroli, Anne Schänzer, Stefan Günther, Claudia García-González, Stefan Rupp, Hannah Schlierbach, Yanpu Chen, Johannes Graumann, Astrid Wietelmann, Johnny Kim et al. · 2024 · Journal of Molecular and Cellular Cardiology
74. Functional analysis of a common BAG3 allele associated with protection from heart failure
    Perez-Bermejo, Juan A., Judge, Luke M., Jensen, Christina L., Wu, Kenneth, Watry, Hannah L., Truong, Annie, Ho, Jaclyn J., Carter, Matthew, Runyon, Wendy V., Kaake, Robyn M. et al. · 2023 · Nature Cardiovascular Research
75. Inflammation and Immunogenetics in Cardiomyopathies: From Molecular Mechanisms to Therapeutic Perspectives
    Peretto, Giovanni, Villatore, Andrea, Cooper, Leslie T. · 2026 · Immunological Reviews
76. Myofibrillar Myopathies and the Z-Disk Associated Proteins
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77. Evaluation of BAG3 levels in healthy subjects, hypertensive patients, and hypertensive diabetic patients
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78. Dilated cardiomyopathy: from genes and molecules to potential treatments
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79. Dilated cardiomyopathy due to a novel combination of TTN and BAG3 genetic variants: From acute heart failure to subclinical phenotypes
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80. 2′-Hydroxycinnamaldehyde, a Natural Product from Cinnamon, Alleviates Ischemia/Reperfusion-Induced Microvascular Dysfunction and Oxidative Damage in Rats by Upregulating Cytosolic BAG3 and Nrf2/HO-1
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81. HSC70-JNK-BAG3 complex is critical for cardiomyocyte protection of BAG3 through its PXXP and BAG structural domains
    Lingling Zhao, Jiaona Gu, Xiao-Fang Zhu, Yin Hu, Hong Wei Cao, Na Yao, Hua Sang, Beibei Guo, Yuhang Wang, Hong-Yan Qian et al. · 2021 · Frontiers in Bioscience-Landmark
82. BAG3 Attenuates Ischemia-Induced Skeletal Muscle Necroptosis in Diabetic Experimental Peripheral Artery Disease
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    Solenn M. Guilbert, Alice‐Anaïs Varlet, Margit Fuchs, Herman Lambert, Jacques Landry, Josée N. Lavoie · 2015 · Heat shock proteins
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    Xue Dong Jiang, Yihuan Chen, Xiaofeng Liu, Lingqun Ye, Miao Yu, Zhenya Shen, Wei Lei, Shijun Hu · 2021 · Frontiers in Cell and Developmental Biology
85. Transcriptome studies of inherited dilated cardiomyopathies
    Matthew Koslow, David Mondaca‐Ruff, Xiaolei Xu · 2023 · Mammalian Genome
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    Ji-Ye Baek, Hye Hyeon Yun, Chang‐Nim Im, Jeong‐Heon Ko, Seung Min Jeong, Jeong Hwa Lee · 2017 · Molecular & Cellular Toxicology
87. Deletion of thebisgene results in a marked increase in the production of corticosterone that is associated with thymic atrophy in mice
    Dong‐Ye Youn, Jung‐Sook Yoon, Yong Kwan Kim, Chung Eun Yeum, Seong‐Beom Lee, Ho‐Joong Youn, Yoshihide Tsujimoto, Jeong‐Hwa Lee · 2011 · American Journal of Physiology-Endocrinology and Metabolism
88. The PXXP domain is critical for the protective effect of BAG 3 in cardiomyocytes
    Eran Ni, Lingling Zhao, Na Yao, Xiaofang Zhu, Hong Wei Cao, Shuzhen Sun, Weizhong Zhu · 2018 · Clinical and Experimental Pharmacology and Physiology
89. Evidence for the impact of BAG3 on electrophysiological activity of primary culture of neonatal cardiomyocytes
    Farzaneh G. Tahrir, Jennifer Gordon, Arthur Michael Feldman, Joseph Y. Cheung, Kamel Khalili, Taha Mohseni Ahooyi · 2019 · Journal of Cellular Physiology
90. MicroRNA regulation of BAG3
    Madhu V. Singh, Karthik Dhanabalan, Joseph P. Verry, Ayotunde O. Dokun · 2022 · Experimental Biology and Medicine
91. BAG3 Myopathy Presenting With Prominent Neuropathic Phenotype and No Cardiac or Respiratory Involvement: A Case Report and Literature Review
    Lindsay Malatesta, Kapil Arya, Murat Gökden, Vikki Stefans, Aravindhan Veerapandiyan · 2020 · Journal of Clinical Neuromuscular Disease
92. Neuromuscular Disease Models and Analysis
    Robert W. Burgess, Gregory A. Cox, Kevin L. Seburn · 2016 · Methods in molecular biology
93. BAG3 regulates ECM accumulation in renal proximal tubular cells induced by TGF-β1.
    Feng Du, Si Li, Tian Wang, Haiyan Zhang, Detian Li, Zhen‐Xian Du, Hua‐Qin Wang, Yanqiu Wang · 2015 · PubMed Central
94. BAG3 in the Heart
    Maria Caterina Turco · 2023 · JACC Basic to Translational Science
95. Bioinformatics analysis of the clinicopathological and prognostic significance of BAG3 mRNA in gynecological cancers
    Zimo Wang, Li Zhang, Dong-hui Ren, Congyu Zhang, Hua‐chuan Zheng · 2023 · Journal of Obstetrics and Gynaecology
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    Dafne Ruggiero, Emis Ingenito, Eleonora Boccia, Vincenzo Vestuto, Gilda D’Urso, Alessandra Capuano, Agostino Casapullo, Stefania Terracciano, Giuseppe Bifulco, Gianluigi Lauro et al. · 2025 · European Journal of Medicinal Chemistry
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    Jiao Lu, Liumei Zhang, Jingjing Liu, Yuting Liu, Xiao-ye Lin, Xueqi Wang, Yuan Zhang, Qiang Tang, Lin Liu · 2023 · The Journal of Physiological Sciences
98. Skeletal Muscle-Specific Bis Depletion Leads to Muscle Dysfunction and Early Death Accompanied by Impairment in Protein Quality Control
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99. AZD7762 induces CRBN dependent BAG3 degradation through ubiquitin-proteasome pathway
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100. SRSF3 Is a Critical Requirement for Inclusion of Exon 3 of BIS Pre-mRNA
     Ji-Ye Baek, Hye Hyeon Yun, Soon-Young Jung, Jeehan Lee, Kyunghyun Yoo, Jeong Hwa Lee · 2020 · Cells