Interferon-γ and Tumor Necrosis Factor-α Regulate Amyloid-β Plaque Deposition and β-Secretase Expression in Swedish Mutant APP Transgenic Mice

Yamamoto, Masaru, Kiyota, Tomomi, Horiba, Masahide, Buescher, James L., Walsh, Shannon M., Gendelman, Howard E., Ikezu, Tsuneya·2007·The American Journal of Pathology

Cited by (366)

Items 101–200 of 366

  1. Infectious origin of Alzheimer’s disease: Amyloid beta as a component of brain antimicrobial immunity
    Vojtechova, Iveta, Machacek, Tomas, Kristofikova, Zdenka, Stuchlik, Ales, Petrasek, Tomas · 2022 · PLOS Pathogens
  2. The Role of ERK1/2 Pathway in the Pathophysiology of Alzheimer’s Disease: An Overview and Update on New Developments
    Mohammad Rafi Khezri, Keyvan Yousefi, Ayda Esmaeili, Morteza Ghasemnejad‐Berenji · 2022 · Cellular and Molecular Neurobiology
  3. Spatial Learning Impairment, Enhanced CDK5/p35 Activity, and Downregulation of NMDA Receptor Expression in Transgenic Mice Expressing Tau-Tubulin Kinase 1
    Shinji Sato, Jiqing Xu, Satoshi Okuyama, Lindsey B. Martinez, Shannon M. Walsh, Michael T. Jacobsen, Russell J. Swan, Joshua D. Schlautman, Pawel S. Ciborowski, Tsuneya Ikezu · 2008 · Journal of Neuroscience
  4. Macrophage migration inhibitory factor in mild cognitive impairment and Alzheimer’s disease
    Julius Popp, Michael Bacher, Heike Kölsch, Carmen Noelker, Oliver Deuster, Richard C. Dodel, Frank Jessen · 2008 · Journal of Psychiatric Research
  5. Reelin-mediated signaling in neuropsychiatric and neurodegenerative diseases
    Knuesel, Irene · 2010 · Progress in Neurobiology
  6. Association of Cigarette Smoking With Cerebrospinal Fluid Biomarkers of Neurodegeneration, Neuroinflammation, and Oxidation
    Yanlong Liu, Hui Li, Jian Wang, Qing Xue, Xiaoyu Yang, Yimin Kang, Mengjie Li, Jinzhong Xu, Guohua Li, Cunbao Li et al. · 2020 · JAMA Network Open
  7. Amyloid β: one of three danger‐associated molecules that are secondary inducers of the proinflammatory cytokines that mediate <scp>A</scp>lzheimer's disease
    Clark, I A, Vissel, B · 2015 · British Journal of Pharmacology
  8. Real-Time Imaging and Quantification of Amyloid-β Peptide Aggregates by Novel Quantum-Dot Nanoprobes
    Kiyotaka Tokuraku, Meg M. Marquardt, Tsuneya Ikezu · 2009 · PLoS ONE
  9. Activation of microglia and induction of pro-inflammatory cytokines in the hippocampus of type 2 diabetic rats
    In Koo Hwang, Jung Hoon Choi, Sung Min Nam, Ok Kyu Park, Dae Young Yoo, Woosuk Kim, Sun Shin Yi, Moo‐Ho Won, Je Kyung Seong, Yeo Sung Yoon · 2014 · Neurological Research
  10. Simultaneous activation of Nrf2 and elevation of antioxidant compounds for reducing oxidative stress and chronic inflammation in human Alzheimer's disease
    Kedar Nath Prasad · 2016 · Mechanisms of Ageing and Development
  11. Molecular Basis of Etiological Implications in Alzheimer’s Disease: Focus on Neuroinflammation
    Rituraj Niranjan · 2013 · Molecular Neurobiology
  12. Cardiometabolic risk factors and neurodegeneration: a review of the mechanisms underlying diabetes, obesity and hypertension in Alzheimer’s disease
    Patel, Vijay, Edison, Paul · 2024 · Journal of Neurology, Neurosurgery &amp; Psychiatry
  13. The paradox of neuronal insulin action and resistance in the development of aging‐associated diseases
    Sophie Marie Steculorum, Maite Solas, Jens C. Brüning · 2014 · Alzheimer s & Dementia
  14. Hyperbaric oxygen therapy ameliorates pathophysiology of 3xTg-AD mouse model by attenuating neuroinflammation
    Ronit Shapira, Beka Solomon, Shai Efrati, Dan Frenkel, Uri Ashery · 2017 · Neurobiology of Aging
  15. Inhibiting tumor necrosis factor-α before amyloidosis prevents synaptic deficits in an Alzheimer's disease model
    Cavanagh, Chelsea, Tse, Yiu Chung, Nguyen, Huy-Binh, Krantic, Slavica, Breitner, John C.S., Quirion, Remi, Wong, Tak Pan · 2016 · Neurobiology of Aging
  16. Peripheral and central neuroimmune mechanisms in Alzheimer’s disease pathogenesis
    Zhang, Shuo, Gao, Yue, Zhao, Yini, Huang, Timothy Y., Zheng, Qiuyang, Wang, Xin · 2025 · Molecular Neurodegeneration
  17. Exosomal biomarkers in Down syndrome and Alzheimer's disease
    Eric Daniel Hamlett, Aurélie Ledreux, Huntington Potter, Heidi J. Chial, David Patterson, Joaquin Maximiliano Espinosa, Brianne Magouirk Bettcher, Ann‐Charlotte Granholm · 2017 · Free Radical Biology and Medicine
  18. Intraperitoneal injection of IFN-γ restores microglial autophagy, promotes amyloid-β clearance and improves cognition in APP/PS1 mice
    Zitian He, Yunjie Yang, Zhiwei Xing, Zejie Zuo, Rui Wang, Huaiyu Gu, Fangfang Qi, Zhibin Yao · 2020 · Cell Death and Disease
  19. Astrocytes and Microglia: Responses to Neuropathological Conditions
    Sarika Singh, Supriya Swarnkar, Poonam Goswami, Chandishwar Nath · 2011 · International Journal of Neuroscience
  20. Imipramine, in Part through Tumor Necrosis Factor α Inhibition, Prevents Cognitive Decline and β-Amyloid Accumulation in a Mouse Model of Alzheimer's Disease
    François Chavant, Julie Deguil, Stéphanie Pain, Isabelle Ingrand, Serge Milin, Bernard Fauconneau, Marie Christine Pérault‐Pochat, Claire Lafay‐Chebassier · 2009 · Journal of Pharmacology and Experimental Therapeutics
  21. Loss of Interleukin Receptor-Associated Kinase 4 Signaling Suppresses Amyloid Pathology and Alters Microglial Phenotype in a Mouse Model of Alzheimer's Disease
    Brent Cameron, Wayne Tse, Raza Lamb, Xiaoxia Li, Bruce T. Lamb, Gary E. Landreth · 2012 · Journal of Neuroscience
  22. Tumor Necrosis Factor-Induced Cerebral Insulin Resistance in Alzheimer's Disease Links Numerous Treatment Rationales
    Ian A. Clark, Craig Atwood, Richard L. Bowen, Gilberto Paz-Filho, Bryce Vissel · 2012 · Pharmacological Reviews
  23. The anti-inflammatory glycoprotein, CD200, restores neurogenesis and enhances amyloid phagocytosis in a mouse model of Alzheimer's disease
    Megan M. Varnum, Tomomi Kiyota, Kaitlin L. Ingraham Dixie, Seiko Ikezu, Tsuneya Ikezu · 2015 · Neurobiology of Aging
  24. The Periodontal Pathogen Fusobacterium nucleatum Exacerbates Alzheimer’s Pathogenesis via Specific Pathways
    Hongle Wu, Wei Qiu, Xiaofang Zhu, Xiangfen Li, Zhongcong Xie, Isabel Carreras, Alpaslan Dedeoglu, Thomas E. Van Dyke, Yiping Weng Han, Nadeem Y. Karimbux et al. · 2022 · Frontiers in Aging Neuroscience
  25. The potential role of proinflammatory and antiinflammatory cytokines in Alzheimer disease pathogenesis
    Gholamreza Azizi, Abbas Mirshafiey · 2012 · Immunopharmacology and Immunotoxicology
  26. Palmitate-activated astrocytes via serine palmitoyltransferase increase BACE1 in primary neurons by sphingomyelinases
    Li Liu, Rebecca Martin, Christina Chan · 2012 · Neurobiology of Aging
  27. Brain interference: Revisiting the role of IFNγ in the central nervous system
    Susana Monteiro, Susana Roque, Fernanda Marques, Margarida Correia‐Neves, João Cerqueira · 2017 · Progress in Neurobiology
  28. Proteolytic Shedding of ST6Gal-I by BACE1 Regulates the Glycosylation and Function of α4β1 Integrins
    Alencia Vanay Woodard‐Grice, Alexis C. McBrayer, John Wakefield, Ya Zhuo, Susan L. Bellis · 2008 · Journal of Biological Chemistry
  29. Integrated communications between cyclooxygenase‐2 and Alzheimer's disease
    Pei-Pei Guan, Pu Wang · 2018 · The FASEB Journal
  30. The effects of Acorus calamus L. in preventing memory loss, anxiety, and oxidative stress on lipopolysaccharide-induced neuroinflammation rat models
    Amir Mokhtarian, Ebrahim Esfandiari, Mustafa Ghanadian, Bahman Rashidi, AmirM Vatankhah · 2018 · International Journal of Preventive Medicine
  31. AAV1/2-mediated CNS Gene Delivery of Dominant-negative CCL2 Mutant Suppresses Gliosis, β-amyloidosis, and Learning Impairment of APP/PS1 Mice
    Tomomi Kiyota, Masaru Yamamoto, Bryce Schroder, Michael T. Jacobsen, Russell J. Swan, Mary P. Lambert, William L. Klein, Howard Eliot Gendelman, Richard M. Ransohoff, Tsuneya Ikezu · 2009 · Molecular Therapy
  32. Total saponins from Rhizoma Anemarrhenae ameliorate diabetes-associated cognitive decline in rats: Involvement of amyloid-beta decrease in brain
    Yao‐Wu Liu, Xia Zhu, Qian Lü, Jianyun Wang, Wei Li, Yaqin Wei, Xiaoxing Yin · 2011 · Journal of Ethnopharmacology
  33. Perispinal etanercept: a new therapeutic paradigm in neurology
    Edward Lewis Tobinick · 2010 · Expert Review of Neurotherapeutics
  34. CX3CL1/CX3CR1 in Alzheimer’s Disease: A Target for Neuroprotection
    Peiqing Chen, Wenjuan Zhao, Yanjie Guo, Juan Xu, Ming Yin · 2016 · BioMed Research International
  35. Hydrogen sulfide inhibits ATP-induced neuroinflammation and Aβ1–42 synthesis by suppressing the activation of STAT3 and cathepsin S
    Lei Cao, Xu Cao, Ye‐Bo Zhou, Bhushan Vijay Nagpure, Zhiyuan Wu, Li Fang Hu, Yong Yang, Gautam Sethi, Philp K. Moore, Jin‐Song Bian · 2018 · Brain Behavior and Immunity
  36. Neuroprotective Activity of Sitagliptin via Reduction of Neuroinflammation beyond the Incretin Effect: Focus on Alzheimer’s Disease
    Michał Wiciński, Eryk Wódkiewicz, Maciej Słupski, Maciej Walczak, Maciej Władysław Socha, Bartosz Malinowski, Katarzyna Pawlak-Osińska · 2018 · BioMed Research International
  37. MyD88 Deficiency Ameliorates β-Amyloidosis in an Animal Model of Alzheimer's Disease
    Lim, Jeong-Eun, Kou, Jinghong, Song, Min, Pattanayak, Abhinandan, Jin, Jingji, Lalonde, Robert, Fukuchi, Ken-ichiro · 2011 · The American Journal of Pathology
  38. Neuropsychiatric symptoms in dementia—A role for neuroinflammation?
    Simon Holmgren, Erik Hjorth, Marianne Schultzberg, Marie Lärksäter, Dan Frenkel, Ann Christine Tysen-Bäckström, Dag Aarsland, Yvonne Freund‐Levi · 2014 · Brain Research Bulletin
  39. Genetic Deletion of Tumor Necrosis Factor-α Attenuates Amyloid-β Production and Decreases Amyloid Plaque Formation and Glial Response in the 5XFAD Model of Alzheimer’s Disease
    Evi Paouri, Ourania Tzara, Sofia Zenelak, Spiros Georgopoulos · 2017 · Journal of Alzheimer s Disease
  40. Presenilin 2 Is the Predominant γ-Secretase in Microglia and Modulates Cytokine Release
    Suman Jayadev, Amanda Case, Alison J. Eastman, Huy Nguyen, Julia Pollak, Jesse C. Wiley, Thomas Möller, Richard S. Morrison, Gwenn A. Garden · 2010 · PLoS ONE
  41. The impact of neuroimmune changes on development of amyloid pathology; relevance to A lzheimer's disease
    Marina A. Lynch · 2013 · Immunology
  42. Adalimumab improves cognitive impairment, exerts neuroprotective effects and attenuates neuroinflammation in an Aβ1-40-injected mouse model of Alzheimer's disease
    Jiae Park, Sun‐Young Lee, Jeeheun Shon, Koeun Kim, Hyo Jin Lee, Kyung‐Ah Kim, Boo-Yong Lee, Seung‐Hun Oh, NAM KEUN KIM, Ok Joon Kim · 2019 · Cytotherapy
  43. Wharton’s Jelly-derived mesenchymal stem cells alleviate memory deficits and reduce amyloid-β deposition in an APP/PS1 transgenic mouse model
    Zhaohong Xie, Zhen Liu, Xiaoran Zhang, Hui Yang, LiFei Wei, Yun Wang, Shunliang Xu, Lin Sun, Chao Lai, Jianzhong Bi et al. · 2015 · Clinical and Experimental Medicine
  44. Anti-inflammatory and anti-amyloidogenic effects of a small molecule, 2,4-bis(p-hydroxyphenyl)-2-butenal in Tg2576 Alzheimer’s disease mice model
    Jin, Peng, Kim, Jin-A, Choi, Dong-Young, Lee, Young-Jung, Jung, Heon Sang, Hong, Jin Tae · 2013 · Journal of Neuroinflammation
  45. Interferon-Driven Immune Dysregulation in Down Syndrome: A Review of the Evidence
    Howard Chung, Peter H R Green, Timothy Cragin Wang, Xiao‐Fei Kong · 2021 · Journal of Inflammation Research
  46. Natural barrigenol–like triterpenoids: A comprehensive review of their contributions to medicinal chemistry
    Xinxin Zhang, Song Zhang, Yiren Yang, Da Wang, Huiyuan Gao · 2019 · Phytochemistry
  47. Plasma rich in growth factors (PRGF-Endoret) reduces neuropathologic hallmarks and improves cognitive functions in an Alzheimer's disease mouse model
    Eduardo Anitua, Consuelo Pascual, Desireé Antequera, Marta Bolós, Sabino Padilla, Gorka Orive, Eva Carro · 2014 · Neurobiology of Aging
  48. Inflammatory Risk Factors and Pathologies Associated with Alzheimers Disease
    Magdalena Sastre, Jill C. Richardson, Steve Gentleman, David James Brooks · 2011 · Current Alzheimer Research
  49. Nutrients, Microglia Aging, and Brain Aging
    Zhou Wu, Janchun Yu, Aiqin Zhu, Hiroshi Nakanishi · 2016 · Oxidative Medicine and Cellular Longevity
  50. Review: Experimental manipulations of microglia in mouse models of <scp>A</scp>lzheimer's pathology: activation reduces amyloid but hastens tau pathology
    Lee, D. C., Rizer, J., Hunt, J. B., Selenica, M.‐L. B., Gordon, M. N., Morgan, D. · 2013 · Neuropathology and Applied Neurobiology
  51. STAT3 activation in microglia exacerbates hippocampal neuronal apoptosis in diabetic brains
    Jang‐Hyuk Yun, Da‐Hye Lee, Han‐Seok Jeong, Hye Sun Kim, Sang‐Kyu Ye, Chung‐Hyun Cho · 2021 · Journal of Cellular Physiology
  52. Distinct Expression of Long Non-Coding RNAs in an Alzheimer's Disease Model
    Doo Young Lee, Jangsup Moon, Soon‐Tae Lee, Keun‐Hwa Jung, Dong-Kyu Park, Jung-Seok Yoo, Jun‐Sang Sunwoo, Jung‐Ick Byun, Jung-Won Shin, Daejong Jeon et al. · 2015 · Journal of Alzheimer s Disease
  53. Altered levels and distribution of amyloid precursor protein and its processing enzymes in Niemann‐Pick type C1‐deficient mouse brains
    Anitha Kodam, Mahua Maulik, Kyle Peake, A. Amritraj, Kulandaivelu S. Vetrivel, Gopal Thinakaran, Jean E. Vance, Satyabrata Kar · 2010 · Glia
  54. Neuroprotective and Anti-Inflammatory Effects of Low–Moderate Dose Ionizing Radiation in Models of Alzheimer’s Disease
    Sujin Kim, Yunkwon Nam, Chanyang Kim, Hyewon Lee, Seo-Jin Hong, Hyeon soo Kim, Soo Jung Shin, Yong Ho Park, Han Ngoc Mai, Sang‐Muk Oh et al. · 2020 · International Journal of Molecular Sciences
  55. Deletion of <i>Abi3</i> gene locus exacerbates neuropathological features of Alzheimer’s disease in a mouse model of Aβ amyloidosis
    Karahan, Hande, Smith, Daniel C., Kim, Byungwook, Dabin, Luke C., Al-Amin, Md Mamun, Wijeratne, H. R. Sagara, Pennington, Taylor, Viana di Prisco, Gonzalo, McCord, Brianne, Lin, Peter Bor-chian et al. · 2021 · Science Advances
  56. Alzheimer’s Disease: A Molecular View of β-Amyloid Induced Morbific Events
    Rajmohamed Mohamed Asik, Natarajan Suganthy, Mohamed Asik Aarifa, Arvind Kumar, Krisztián Szigeti, Domokos Máthé, Balázs Zoltán Gulyás, Govindaraju Archunan, Parasuraman Padmanabhan · 2021 · Biomedicines
  57. RETRACTED: Multiple inflammatory pathways are involved in the development and progression of cognitive deficits in APPswe/PS1dE9 mice
    Wei Zhang, Miao Bai, Xi Ye, Jian Hao, Zhuo Zhang, Changjun Su, Gesheng Lei, Jianting Miao, Zhuyi Li · 2012 · Neurobiology of Aging · Retracted
  58. The Association between TNF-alpha, IL-1 alpha and IL-10 with Alzheimer's Disease
    Marija Čuljak, Matea Nikolac Perković, Suzana Uzun, Dubravka Švob Štrac, Gordana Nedić Erjavec, Mirjana Babić Leko, Goran Šimić, Lucija Tudor, Marcela Konjevod, Oliver Kozumplik et al. · 2020 · Current Alzheimer Research
  59. 4-O-Methylhonokiol attenuates memory impairment in presenilin 2 mutant mice through reduction of oxidative damage and inactivation of astrocytes and the ERK pathway
    Young Jung Lee, Im Seop Choi, Mi Hee Park, Yuk-Mo Lee, Ju Kyoung Song, Young Hee Kim, Ki Ho Kim, Dae Yeon Hwang, Jae Hwang Jeong, Yeo Pyo Yun et al. · 2010 · Free Radical Biology and Medicine
  60. Brain Protection in Schizophrenia, Mood and Cognitive Disorders
    Michael S. Ritsner · 2010 · Springer eBooks
  61. Anti-Neuroinflammatory Potential of Polyphenols by Inhibiting NF-Κb to Halt Alzheimer's Disease
    Uddin, Md. Sahab, Hasana, Sharifa, Ahmad, Jamil, Hossain, Md. Farhad, Rahman, Md. Mosiqur, Behl, Tapan, Rauf, Abdur, Ahmad, Ausaf, Hafeez, Abdul, Perveen, Asma et al. · 2021 · Current Pharmaceutical Design
  62. Anti-Amyloidogenic Effect of Thiacremonone through Anti-Inflamation In Vitro and In Vivo Models
    Gui Hua Lin, Young‐Jung Lee, Dong‐Young Choi, Sang‐Bae Han, Jae‐Kyung Jung, Bang Yeon Hwang, Dong Cheul Moon, Young Soo Kim, Myung Koo Lee, Ki‐Wan Oh et al. · 2012 · Journal of Alzheimer s Disease
  63. Morin post-treatment confers neuroprotection in a novel rat model of mild repetitive traumatic brain injury by targeting dementia markers, APOE, autophagy and Wnt/β-catenin signaling pathway
    Amira A. El-Gazar, Ayman A. Soubh, Eman A. Mohamed, Azza Sayed Awad, Hanan Salah El-Abhar · 2019 · Brain Research
  64. Microglia in Alzheimer's Disease: a Key Player in the Transition Between Homeostasis and Pathogenesis
    McFarland, Karen N., Chakrabarty, Paramita · 2022 · Neurotherapeutics
  65. Apolipoprotein D modulates amyloid pathology in APP/PS1 Alzheimer's disease mice
    Hongyun Li, Kalani R. Ruberu, Sonia Sanz Muñoz, Andrew M. Jenner, Adena S. Spiro, Hua Zhao, Éric Rassart, Diego Sánchez, María Dolores Ganfornina, Tim Karl et al. · 2015 · Neurobiology of Aging
  66. TNF-α–mediated reduction in inhibitory neurotransmission precedes sporadic Alzheimer’s disease pathology in young Trem2 rats
    Ren, Siqiang, Breuillaud, Lionel, Yao, Wen, Yin, Tao, Norris, Kelly A., Zehntner, Simone P., D’Adamio, Luciano · 2021 · Journal of Biological Chemistry
  67. Pathophysiological Mechanisms of Cognitive Impairment and Neurodegeneration by Toxoplasma gondii Infection
    Gloria Ortiz‐Guerrero, Rodrigo E. González-Reyes, Alejandra de‐la‐Torre, Germán José Medina-Rincón, Mauricio O. Nava-Mesa · 2020 · Brain Sciences
  68. Bacterial sepsis increases hippocampal fibrillar amyloid plaque load and neuroinflammation in a mouse model of Alzheimer’s disease
    Basak, Jacob M., Ferreiro, Aura, Cohen, Lucy S., Sheehan, Patrick W., Nadarajah, Collin J., Kanan, Michael F., Sukhum, Kimberley V., Dantas, Gautam, Musiek, Erik S. · 2021 · Neurobiology of Disease
  69. Microglia-Mediated Neurovascular Unit Dysfunction in Alzheimer’s Disease
    Wenhao Huang, Qing Xia, Feifei Zheng, Xue Ling Zhao, Fangliang Ge, Jiaying Xiao, Zijie Liu, Ying‐Ying Shen, Ke Ye, Dayong Wang et al. · 2023 · Journal of Alzheimer s Disease
  70. Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease
    Harsh Shah, Fereshteh Dehghani, Marjan Ramezan, Ritchel B. Gannaban, Zobayda Farzana Haque, Fatemeh Chitgar Rahimi, Soheil Abbasi, Andrew Changhun Shin · 2023 · Antioxidants
  71. TREM2 analysis and increased risk of Alzheimer's disease
    Deana Finelli, Sara J. Rollinson, Jenny Harris, Matthew S. Jones, Anna M. T. Richardson, Alexander Gerhard, Julie S. Snowden, David M. A. Mann, Stuart M. Pickering-Brown · 2014 · Neurobiology of Aging
  72. Xanthoceraside Inhibits Pro-inflammatory Cytokine Expression in Aβ25–35/IFN-γ–Stimulated Microglia Through the TLR2 Receptor, MyD88, Nuclear Factor-κB, and Mitogen-Activated Protein Kinase Signaling Pathways
    Yue Andy Qi, Libo Zou, Lihua Wang, Ge Jin, Jinjin Pan, Tianyan Chi, Xuefei Ji · 2013 · Journal of Pharmacological Sciences
  73. Amyloidosis in Retinal Neurodegenerative Diseases
    Ambra Masuzzo, Virginie Dinet, Chelsea Cavanagh, Frédéric Mascarelli, Slavica M Krantic · 2016 · Frontiers in Neurology
  74. Role of neurotoxicants in the pathogenesis of Alzheimer’s disease: a mechanistic insight
    Fatema Yasmin Nisa, Md. Atiar Rahman, Md. Amjad Hossen, Mohammad Forhad Khan, Md. Asif Nadim Khan, Mumtahina Majid, Farjana Sultana, Md. Areeful Haque · 2021 · Annals of Medicine
  75. Gallic acid and hesperidin elevate neurotransmitters level and protect against oxidative stress, inflammation and apoptosis in aluminum chloride-induced Alzheimer's disease in rats
    Bidemi Emmanuel Ekundayo, Tajudeen Olabisi Obafemi, Blessing Augustine Afolabi, Olusola Bolaji Adewale, A. Onasanya, Olukemi Adetutu Osukoya, John Adeolu Falode, Christopher Oloruntoba Akintayo, Isaac Adekola Adu · 2022 · Pharmacological Research - Modern Chinese Medicine
  76. Possible role of P-glycoprotein in the neuroprotective mechanism of berberine in intracerebroventricular streptozotocin-induced cognitive dysfunction
    Anil Kumar, Ekavali, Jitendriya Mishra, Kanwaljit Chopra, Dinesh Kumar Dhull · 2015 · Psychopharmacology
  77. Piperlongumine Improves Lipopolysaccharide-Induced Amyloidogenesis by Suppressing NF-KappaB Pathway
    Sun Mi Gu, Hee Pom Lee, Young Wan Ham, Dong Ju Son, Hoi Yeong Kim, Ki Wan Oh, Sang‐Bae Han, Jaesuk Yun, Jin Tae Hong · 2018 · NeuroMolecular Medicine
  78. Systems Pharmacology Approach to Investigate the Mechanism of Kai-Xin-San in Alzheimer’s Disease
    Yunxia Luo, Dongli Li, Yanfang Liao, Chuipu Cai, Qihui Wu, Hanzhong Ke, Xinning Liu, Hui-Lin Li, Honghai Hong, Yumin Xu et al. · 2020 · Frontiers in Pharmacology
  79. βCTF-Correlated Burst of Hippocampal TNFα Occurs at a Very Early, Pre-Plaque Stage in the TgCRND8 Mouse Model of Alzheimer's Disease
    Chelsea Cavanagh, Jessica Colby-Milley, David S. Bouvier, Mark C. Farso, Jean‐Guy Chabot, Rémi Quirion, Slavica M Krantic · 2013 · Journal of Alzheimer s Disease
  80. Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer’s disease by meta-analysis and adaptive boosting ensemble learning
    Sze Chung Yuen, Xiaonan Liang, Hongmei Zhu, Yongliang Jia, Siu-wai Leung · 2021 · Alzheimer s Research & Therapy
  81. Metformin in Alzheimer’s disease: An overview of potential mechanisms, preclinical and clinical findings
    Mohammad Rafi Khezri, Keyvan Yousefi, Negin Mahboubi, Darya Hodaei, Morteza Ghasemnejad‐Berenji · 2022 · Biochemical Pharmacology
  82. Tau‐tubulin kinase 1 enhances prefibrillar tau aggregation and motor neuron degeneration in P301L FTDP‐17 tau‐mutant mice
    Jiqing Xu, Shinji Sato, Satoshi Okuyama, Russell J. Swan, Michael T. Jacobsen, Elena Strunk, Tsuneya Ikezu · 2010 · The FASEB Journal
  83. Die Alzheimer‐Demenz: von der Pathologie zu therapeutischen Ansätzen
    Roland Jakob‐Roetne, Helmut Jacobsen · 2009 · Angewandte Chemie
  84. Molecular Bases of Alzheimer’s Disease and Neurodegeneration: The Role of Neuroglia
    Antonina Luca, Carmela Calandra, Maria Luca · 2018 · Aging and Disease
  85. Neuroinflammatory Cytokines - The Common Thread in Alzheimer Pathogenesis
    W. Sue T. Griffin, Steven W. Barger, Dillard Professor and Vice Chairman · 2011 · European Neurological Review
  86. The endocrine dyscrasia that accompanies menopause and andropause induces aberrant cell cycle signaling that triggers re-entry of post-mitotic neurons into the cell cycle, neurodysfunction, neurodegeneration and cognitive disease
    Craig Atwood, Richard L. Bowen · 2015 · Hormones and Behavior
  87. Amyloid Precursor Protein Is Required for Normal Function of the Rod and Cone Pathways in the Mouse Retina
    Tracy Ho, Kirstan A. Vessey, Roberto Cappai, Virginie Dinet, Frédéric Mascarelli, Giuseppe D. Ciccotosto, Erica Lucy Fletcher · 2012 · PLoS ONE
  88. Increased Plasma TACE Activity in Subjects with Mild Cognitive Impairment and Patients with Alzheimer's Disease
    Qiying Sun, Harald Juergen Hampel, Kaj Blennow, Simone Lista, Allan I. Levey, Beisha Tang, Rena Li, Yong Shen · 2014 · Journal of Alzheimer s Disease
  89. Astrocytes infected with Chlamydia pneumoniae demonstrate altered expression and activity of secretases involved in the generation of β-amyloid found in Alzheimer disease
    Al-Atrache, Zein, Lopez, Danielle B., Hingley, Susan T., Appelt, Denah M. · 2019 · BMC Neuroscience
  90. Identification of inflammatory and vascular markers associated with mild cognitive impairment
    Xue‐Ning Shen, Yanxia Lu, Crystal Tze Ying Tan, Ling-yun Liu, Jin‐Tai Yu, Lei Feng, Anis Larbi · 2019 · Aging
  91. Interaction of NF-κB and Wnt/β-catenin Signaling Pathways in Alzheimer’s Disease and Potential Active Drug Treatments
    Xiao Liu, Kaiyue Wang, Xing Wei, Tian Xie, Bin Lv, Qian Zhou, Xiaoying Wang · 2021 · Neurochemical Research
  92. Potential Immunotargets for Alzheimer's Disease Treatment Strategies
    Patricia L. Fernández, Gabrielle B. Britton, K. S. Jagannatha Rao · 2012 · Journal of Alzheimer s Disease
  93. Plasma Acetylcholinesterase Activity Correlates with Intracerebral β-Amyloid Load
    Adi Alkalay, Gil Dan Rabinovici, Gabriel Zimmerman, Neha Agarwal, Daniela Kaufer, Bruce L. Miller, William J. Jagust, Hermona Soreq · 2013 · Current Alzheimer Research
  94. Repurposing Immunomodulatory Imide Drugs (IMiDs) in Neuropsychiatric and Neurodegenerative Disorders
    Yoo Jin Jung, David Tweedie, Michael T. Scerba, Dong Seok Kim, Maria Francesca Palmas, Augusta Pisanu, Anna Rosa Carta, Nigel H. Greig · 2021 · Frontiers in Neuroscience
  95. Gamma Interferon Signaling in Macrophage Lineage Cells Regulates Central Nervous System Inflammation and Chemokine Production
    Adora A. Lin, Pulak Tripathi, Allyson Sholl, Michael B. Jordan, David A. Hildeman · 2009 · Journal of Virology
  96. Dantrolene : From Malignant Hyperthermia to Alzheimer’s Disease
    Yun Shi, Yong Wang, Huafeng Wei · 2018 · CNS & Neurological Disorders - Drug Targets
  97. Coxsackievirus Adenovirus Receptor Loss Impairs Adult Neurogenesis, Synapse Content, and Hippocampus Plasticity
    Charleine Zussy, Fabien Loustalot, Fèlix Junyent, Fabrizio Gardoni, Cyril Bories, Jorge Valero, Michel G. Desarménien, Florence Bernex, Daniel Henaff, Neus Bayó-Puxan et al. · 2016 · Journal of Neuroscience
  98. Interferon Gamma: Influence on Neural Stem Cell Function in Neurodegenerative and Neuroinflammatory Disease
    Apurva Kulkarni, Priya Ganesan, Lauren A. O’Donnell · 2016 · Clinical Medicine Insights Pathology
  99. Perindopril ameliorates experimental Alzheimer’s disease progression: role of amyloid β degradation, central estrogen receptor and hyperlipidemic-lipid raft signaling
    Basim Anwar Shehata Messiha, Mohammed R.A. Ali, Mahmoud Mohamed Khattab, Amira M. Abo‐Youssef · 2020 · Inflammopharmacology
  100. Astrocyte subtype-specific approach to Alzheimer's disease treatment
    Sukanya Sarkar, Subhas Chandra Biswas · 2021 · Neurochemistry International