CX3CR1 Deficiency Alters Microglial Activation and Reduces Beta-Amyloid Deposition in Two Alzheimer's Disease Mouse Models

Lee, Sungho, Varvel, Nicholas H., Konerth, Megan E., Xu, Guixiang, Cardona, Astrid E., Ransohoff, Richard M., Lamb, Bruce T.·2010·The American Journal of Pathology

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  67. Animal Models of Alzheimer’s Disease: Utilization of Transgenic Alzheimer’s Disease Models in Studies of Amyloid Beta Clearance
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