CX3CR1 Deficiency Alters Microglial Activation and Reduces Beta-Amyloid Deposition in Two Alzheimer's Disease Mouse Models
Lee, Sungho, Varvel, Nicholas H., Konerth, Megan E., Xu, Guixiang, Cardona, Astrid E., Ransohoff, Richard M., Lamb, Bruce T.·2010·The American Journal of Pathology
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- Prevention of C5aR1 signaling delays microglial inflammatory polarization, favors clearance pathways and suppresses cognitive lossMichael X. Hernandez, Shan Jiang, Tracy A. Cole, Shu‐Hui Chu, Maria I. Fonseca, Melody J. Fang, Lindsay A. Hohsfield, Maria D. Torres, Kim N. Green, Rick A. Wetsel et al. · 2017 · Molecular Neurodegeneration
- <i>Cx3cr1-</i>
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- Innate Immunity Fights Alzheimer's DiseaseMarie‐Victoire Guillot‐Sestier, Kevin R. Doty, Terrence Town · 2015 · Trends in Neurosciences
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- Role of Atypical Chemokine Receptors in Microglial Activation and PolarizationValentina Salvi, Francesca Sozio, Silvano Sozzani, Annalisa Del Prete · 2017 · Frontiers in Aging Neuroscience
- The complex contribution of chemokines to neuroinflammation: switching from beneficial to detrimental effectsOphélia Le Thuc, Nicolas Blondeau, Jean‐Louis Nahon, Carole Rovère · 2015 · Annals of the New York Academy of Sciences
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- Microglia in Alzheimer's Disease: It's All About ContextWeitz, Tara M., Town, Terrence · 2012 · International Journal of Alzheimer's Disease
- Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brainMaj‐Linda B. Selenica, Jennifer A. Alvarez, Kevin R. Nash, Daniel C. Lee, Chuanhai Cao, Xiaoyang Lin, Patrick Reid, Peter R. Mouton, David Morgan, Marcia N. Gordon · 2013 · Journal of Neuroinflammation
- A Brief History of Microglial Ultrastructure: Distinctive Features, Phenotypes, and Functions Discovered Over the Past 60 Years by Electron MicroscopyJulie C. Savage, Katherine Picard, Fernando Gonzàlez Ibáñez, Marie‐Ève Tremblay · 2018 · Frontiers in Immunology
- A novel in vitro human microglia model: Characterization of human monocyte-derived microgliaSamar Etemad, Rasheeda Mohd Zamin, Marc Jan Ruitenberg, Luis Filgueira · 2012 · Journal of Neuroscience Methods
- Fractalkine/<scp>CX</scp>3<scp>CL</scp>1 modulates <scp>GABA</scp><sub>A</sub> currents in human temporal lobe epilepsyRoseti, Cristina, Fucile, Sergio, Lauro, Clotilde, Martinello, Katiuscia, Bertollini, Cristina, Esposito, Vincenzo, Mascia, Addolorata, Catalano, Myriam, Aronica, Eleonora, Limatola, Cristina et al. · 2013 · Epilepsia
- Loss of tau rescues inflammation-mediated neurodegenerationMaphis, Nicole, Xu, Guixiang, Kokiko-Cochran, Olga N., Cardona, Astrid E., Ransohoff, Richard M., Lamb, Bruce T., Bhaskar, Kiran · 2015 · Frontiers in Neuroscience
- Macrophages in cardiac homeostasis, injury responses and progenitor cell mobilisationAlexander Ruvantha Pinto, James W. Godwin, Nadia A Rosenthal · 2014 · Stem Cell Research
- Role of fractalkine–CX3CR1 pathway in seizure-induced microglial activation, neurodegeneration, and neuroblast production in the adult rat brainIdrish Yunus Ali, Deepti Chugh, Christine T. Ekdahl · 2014 · Neurobiology of Disease
- Cortical microhemorrhages cause local inflammation but do not trigger widespread dendrite degenerationRosidi, Nathanael L., Zhou, Joan, Pattanaik, Sanket, Wang, Peng, Jin, Weiyang, Brophy, Morgan, Olbricht, William L., Nishimura, Nozomi, Schaffer, Chris B. · 2011 · PLoS ONE
- Fractalkine/CX3CR1 is involved in the cross-talk between neuron and glia in neurological diseases.Piao Luo, Shi-Feng Chu, Zhao Zhang, Cong-yuan Xia, Nai-Hong Chen · 2019 · Brain Research Bulletin
- Role of CX3CL1 in DiseasesWangmi Liu, Libo Jiang, Chong Bian, Yun Liang, Rong Xing, Mumingjiang Yishakea, Jian Dong · 2016 · Archivum Immunologiae et Therapiae Experimentalis
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- The Potential Role of Chemokines in Alzheimer’s Disease PathogenesisGholamreza Azizi, Nikoo Hossein‐Khannazer, Abbas Mirshafiey · 2014 · American Journal of Alzheimer s Disease & Other Dementias®
- Chemokine receptor CXCR2: Physiology regulator and neuroinflammation controller?Mike Veenstra, Richard M. Ransohoff · 2012 · Journal of Neuroimmunology
- Cognitive and Behavioral Consequences of Impaired Immunoregulation in AgingAngela W. Corona, Ashley M. Fenn, Jonathan P. Godbout · 2011 · Journal of Neuroimmune Pharmacology
- Recent Progress in Alzheimer’s Disease Research, Part 1: PathologyFrancis T. Hane, Brenda Yasie Lee, Zoya Leonenko · 2017 · Journal of Alzheimer s Disease
- The Evolving Dialogue of Microglia and Neurons in Alzheimer’s Disease: Microglia as Necessary Transducers of PathologySimon, E., Obst, J., Gomez-Nicola, D. · 2019 · Neuroscience
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- Microglia as a critical player in both developmental and late-life CNS pathologiesDerecki, Noël C., Katzmarski, Natalie, Kipnis, Jonathan, Meyer-Luehmann, Melanie · 2014 · Acta Neuropathologica
- The microglial fractalkine receptor is not required for activity-dependent plasticity in the mouse visual systemRebecca L. Lowery, Marie‐Ève Tremblay, Brittany E. Hopkins, Ania Katarzyna Majewska · 2017 · Glia
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- Amyloid ß and Tau Alzheimer¿s disease related pathology is reduced by toll-like receptor 9 stimulationHenrieta Scholtzova, Peter E. Chianchiano, Jason Pan, Yanjie Sun, Fernando Goñi, Pankaj D Mehta, Thomas Wısnıewskı · 2014 · Acta Neuropathologica Communications
- Hematopoietic CC-Chemokine Receptor 2 (CCR2) Competent Cells Are Protective for the Cognitive Impairments and Amyloid Pathology in a Transgenic Mouse Model of Alzheimer’s DiseaseGaëlle Naert, Serge Rivest · 2011 · Molecular Medicine
- Neuroinflammatory Signaling in the Pathogenesis of Alzheimer’s DiseaseMd. Sahab Uddin, Md. Tanvir Kabir, Maroua Jalouli, Md. Ataur Rahman, Philippe Jeandet, Tapan Behl, Athanasios T. Alexiou, Ghadeer Mohsen Albadrani, Mohamed M. Abdel‐Daim, Asma Perveen et al. · 2021 · Current Neuropharmacology
- Rod microglia and their role in neurological diseasesOlivia G. Holloway, Alison Jane Canty, Anna Elizabeth King, Jenna M. Ziebell · 2019 · Seminars in Cell and Developmental Biology
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- Innate Immunity in Alzheimer’s Disease: A Complex AffairMarie‐Victoire Guillot‐Sestier, Terrence Town · 2013 · CNS & Neurological Disorders - Drug Targets
- Neuroinflammation and Glial Phenotypic Changes in Alpha-SynucleinopathiesVioletta Refolo, Nadia Stefanova · 2019 · Frontiers in Cellular Neuroscience
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- Responses of rat and mouse primary microglia to pro- and anti-inflammatory stimuli: molecular profiles, K+ channels and migrationDoris Lam, Starlee S. Lively, Lyanne C. Schlichter · 2017 · Journal of Neuroinflammation
- The Receptor for Advanced Glycation Endproducts (RAGE) and Mediation of Inflammatory NeurodegenerationDerk, Julia, MacLean, Michael, Juranek, Judyta, Schmidt, Ann Marie · 2018 · Journal of Alzheimer’s Disease & Parkinsonism
- Adult microglial TGFβ1 is required for microglia homeostasis via an autocrine mechanism to maintain cognitive function in miceAlicia Bedolla, Elliot Wegman, Max Weed, Messiyah K. Stevens, Kierra Ware, Aditi Paranjpe, Anastasia Alkhimovitch, Igal Ifergan, Александр Таранов, Joshua D. Peter et al. · 2024 · Nature Communications
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- Targeting Microglia in Alzheimer’s Disease: Pathogenesis and Potential Therapeutic StrategiesSun, Zhongqing, Zhang, Xin, So, Kwok-Fai, Jiang, Wen, Chiu, Kin · 2024 · Biomolecules
- Tyrosine Kinase Inhibition Regulates Early Systemic Immune Changes and Modulates the Neuroimmune Response in α-SynucleinopathyM. Hebron, I. Lonskaya, Paul Olopade, S. Selby, F. Pagán, C. Moussa · 2014 · Journal of Clinical & Cellular Immunology
- Cellular and Molecular Mediators of Neuroinflammation in Alzheimer DiseaseSeung‐Hoon Yang · 2019 · International Neurourology Journal
- CX3CR1‐dependent recruitment of mature NK cells into the central nervous system contributes to control autoimmune neuroinflammationLaura Hertwig, Isabell Hamann, Silvina Romero‐Suárez, Jason Michael Millward, R Pietrek, Coralie Chanvillard, Hanna Stuis, Karolin Pollok, Richard M. Ransohoff, Astrid E. Cardona et al. · 2016 · European Journal of Immunology
- Fractalkine Signaling Regulates the Inflammatory Response in an α-Synuclein Model of Parkinson DiseaseAaron D. Thome, David G. Standaert, Ashley S. Harms · 2015 · PLoS ONE
- Rapid morphologic changes to microglial cells and upregulation of mixed microglial activation state markers induced by P2X7 receptor stimulation and increased intraocular pressureKeith E. Campagno, Wennan Lu, Assraa Hassan Jassim, Farraj Albalawi, Aurora Cenaj, Huen‐Yee Tso, Sophia P. Clark, Puttipong Sripinun, Néstor Más Gómez, Claire H. Mitchell · 2021 · Journal of Neuroinflammation
- The Biphasic Role of Microglia in Alzheimer's DiseaseTetsuya Mizuno · 2012 · International Journal of Alzheimer s Disease
- Therapeutic Potential of Mesenchymal Stromal Cells and MSC Conditioned Medium in Amyotrophic Lateral Sclerosis (ALS) - In Vitro Evidence from Primary Motor Neuron Cultures, NSC-34 Cells, Astrocytes and MicrogliaHui Juan Sun, Karelle Bénardais, Nancy Stanslowsky, Nadine Thau‐Habermann, Niko Hensel, Dongya Huang, Peter Claus, Reinhard Dengler, Martin Stangel, Susanne Petri · 2013 · PLoS ONE
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- CX 3 CR1 deficiency delays acute skeletal muscle injury repair by impairing macrophage functionsWanming Zhao, Haiyan Lu, Xingyu Wang, Richard M. Ransohoff, Lan Zhou · 2015 · The FASEB Journal
- CX3CL1/CX3CR1 in Alzheimer’s Disease: A Target for NeuroprotectionPeiqing Chen, Wenjuan Zhao, Yanjie Guo, Juan Xu, Ming Yin · 2016 · BioMed Research International
- Fractalkine (CX3CL1) signaling and neuroinflammation in Parkinson’s disease: Potential clinical and therapeutic implicationsEfthalia Angelopoulou, Yam Nath Paudel, Mohd. Farooq Shaikh, Christina Piperi · 2020 · Pharmacological Research
- Two forms of CX3CL1 display differential activity and rescue cognitive deficits in CX3CL1 knockout miceAimee N. Winter, Meena S. Subbarayan, Bethany A. Grimmig, Jason A. Weesner, Lauren D. Moss, Melinda M. Peters, Edwin J. Weeber, Kevin R. Nash, Paula C. Bickford · 2020 · Journal of Neuroinflammation
- Neuron-Microglia Dialogue and Hippocampal Neurogenesis in the Aged Brain.Carmelina Gemma, Adam D. Bachstetter, Paula C. Bickford · 2010 · Europe PMC (PubMed Central)
- Real-time analysis of microglial activation and motility in hepatic and hyperammonemic encephalopathyVinita Rangroo Thrane, Alexander Stanley Thrane, J. CHANAG, V. Alleluia, Erlend Arnulf Nagelhus, Maiken Nedergaard · 2012 · Neuroscience