Supplemental creatine monohydrate loading improves cognitive function in experienced mountain bikers
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A number of other studies with omnivore participants or unspecified and presumably omnivore participants also found a large creatine effect.
“Under the same conditions, a number of other studies with omnivore participants [52–55] or unspecified and presumably omnivore participants [56–58] also found a large creatine effect”
From The effects of creatine supplementation on cognitive performance—a randomised controlled study (2023) · cites this paper as [52]
Risk of bias was scored as high in 6 RCTs because information about how randomization was applied was lacking.
“Risk of bias was scored as high in 6 RCTs because information about how randomization was applied was lacking.22,24,25,27,28,30”
From Effects of creatine supplementation on memory in healthy individuals: a systematic review and meta-analysis of randomized controlled trials (2023) · cites this paper as [22]
In 4 RCTs, some concerns were raised because of the absence of detail regarding treatment allocation.
“In 4 RCTs, some concerns were raised because of the absence of detail regarding treatment allocation.22,24,30,34”
From Effects of creatine supplementation on memory in healthy individuals: a systematic review and meta-analysis of randomized controlled trials (2023) · cites this paper as [22]
8 RCTs had a study protocol that was not prespecified, resulting in some concerns.
“Finally, 8 RCTs had a study protocol that was not prespecified, resulting in some concerns.22,24,25,27,28,30,34,36”
From Effects of creatine supplementation on memory in healthy individuals: a systematic review and meta-analysis of randomized controlled trials (2023) · cites this paper as [22]
Cites
Dolan, E., Gualano, B., & Rawson, E. S. (2019) · European Journal of Sport Science · doi:10.1080/17461391.2018.1500644 · Cited by 171 · see citing works
Lactate efflux and the neuroenergetic basis of brain function
Shulman, R. G., Hyder, F., & Rothman, D. L. (2001) · NMR in Biomedicine · doi:10.1002/nbm.741 · Cited by 123 · see citing works
Creatine as a booster for human brain function. How might it work?
Rae, C. D., & Bröer, S. (2015) · Neurochemistry International · doi:10.1016/j.neuint.2015.08.010 · Cited by 108 · see citing works
Balestrino, M., & Adriano, E. (2019) · Medicinal Research Reviews · doi:10.1002/med.21590 · Cited by 90 · see citing works
Creatine Monohydrate Supplementation: Considerations for Cognitive Performance in Athletes
Machek, S. B., & Bagley, J. R. (2018) · Strength and conditioning journal · doi:10.1519/ssc.0000000000000369 · Cited by 10 · see citing works
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Prokopidis, K., Giannos, P., Triantafyllidis, K. K., Kechagias, K. S., Forbes, S. C., & Candow, D. G. (2023) · Nutrition Reviews · doi:10.1093/nutrit/nuac064 · Cited by 71 · see citing works
The effects of creatine supplementation on cognitive performance—a randomised controlled study
Sandkühler, J. F., Kersting, X., Faust, A., Königs, E. K., Altman, G., Ettinger, U., Lux, S., Philipsen, A., Müller, H., & Brauner, J. (2023) · BMC Medicine · doi:10.1186/s12916-023-03146-5 · Cited by 29 · see citing works
“Under the same conditions, a number of other studies with omnivore participants [52–55] or unspecified and presumably omnivore participants [56–58] also found a large creatine effect, while other studies with omnivore participants [21, 59, 60] or unspecified and presumably omnivore participants…”
ResultChun, J., Liu, Y., Kibler, G. L., Lee, H., Babakhani, K., Rhoades, N., Bivins, I., Ko, J., Dickerson, B., Gonzalez, D. E., et al. (2026) · Journal of the International Society of Sports Nutrition · doi:10.1080/15502783.2026.2716273
- Authors
- Borchio, L., Machek, S. B., & Machado, M.
- Affiliations
- Universidade Iguaçu (BR)
- Baylor University (US)
- Venue
- The Journal of Sports Medicine and Physical Fitness
- Publisher
- Edizioni Minerva Medica
- Published
- 2020-09
- Volume
- 60
- Issue
- 8
- Pages
- 1168-1170
- ISSN
- 0022-4707 (ISSN-L)
- 1827-1928
- OpenAlex
- W3087453733
- Cited by
- 23
- References
- 5
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 8 · 2023: 4 · 2022: 5 · 2021: 1
- Type
- supplementary materials
- Language
- en
- Open access
- closed
- Locations
- The Journal of Sports Medicine and Physical Fitness (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Health Sciences › Medicine › Physiology › Biochemical effects in animals
- Keywords
- creatine monohydrate, creatine supplementation, cognitive function, mountain bikers, endurance athletes, cognitive performance
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