Metabolic basis for the essential nature of fatty acids and the unique dietary fatty acid requirements of cats
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Cats are unable to synthesize arachidonic acid due to low Delta-6-desaturase activity.
“One outcome of this adaptive process is that cats are unable to synthesize certain essential fatty acids, specifically arachidonic acid, due to low Delta-6-desaturase activity (27).”
From Comparative analysis of the domestic cat genome reveals genetic signatures underlying feline biology and domestication (2014) · cites this paper as [27]
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Cites
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Biochemistry of Lipids, Lipoproteins and Membranes
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Inability of the cat to desaturate essential fatty acids
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Essential Fatty Acids: The Importance of n-3 Fatty Acids in the Retina and Brain
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Role of essential fatty acids in the function of the developing nervous system
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Health effects of dietary fatty acids
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Effects of Linoleate and Arachidonate Deficiencies on Reproduction and Spermatogenesis in the Cat
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Self-citationDo cats need arachidonic acid in the diet for reproduction?
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Is Dietary Arachidonic Acid Necessary for Feline Reproduction?
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Research works printed but not linked: 3
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Montague, M. J., Li, G., Gandolfi, B., Khan, R., Aken, B. L., Searle, S. M. J., Minx, P., Hillier, L. W., Koboldt, D. C., Davis, B. W., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1410083111 · Cited by 340 · see citing works
- Authors
- Bauer, J. E.
- Affiliations
- Texas A&M University (US)
- Corresponding author
- Bauer, John E.
- Venue
- Journal of the American Veterinary Medical Association
- Published
- 2006-12-01
- Volume
- 229
- Issue
- 11
- Pages
- 1729-1732
- ISSN
- 0003-1488 (ISSN-L)
- OpenAlex
- W2083712050
- Cited by
- 35
- References
- 18
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 3 · 2023: 3 · 2022: 2 · 2021: 5 · 2019: 1 · 2015: 3 · 2014: 4 · 2013: 2 · 2012: 2
- FWCI
- 0.00
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Journal of the American Veterinary Medical Association (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Veterinary › Small Animals › Veterinary Medicine and Surgery
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Lipid metabolism and biosynthesis
- Keywords
- fatty acids, essential fatty acids, dietary fatty acid requirements, cats, feline nutrition, lipid metabolism
- MeSH terms
- Animals, Cat Diseases, Cats, Fatty Acids, Essential, Female, Male, Nutritional Requirements, Fatty Acids, Omega-3, Arachidonic Acid, Linoleic Acid
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