New disability weights for the global burden of disease
Open accessAbstract
Since its launch in the early 1990s, the global burden of disease study has produced a highly influential set of findings on the impacts of different diseases, injuries and risk factors on population health.1–3 One important contribution of the study has been the development of the disability-adjusted life year (DALY) as a new metric for quantifying losses of healthy life, due either to premature mortality or to time lived in a state of reduced health. To account for both types of outcomes in a commensurable way, DALYs require a set of numerical weights attached to the wide array of non-fatal consequences from different diseases and injuries. The conceptualization and measurement of these “disability weights” have prompted considerable commentary and debate.4–6 At present, studies on the global, regional or national burden of disease continue to draw heavily on the set of disability weights derived in the 1996 revision of The global burden of disease.7 For the 1996 study, a panel of health professionals developed these disability weights in a deliberative group exercise. First they evaluated 22 indicator conditions using a method called the “person trade-off”. Based on the resulting values, the 22 conditions were then grouped into seven different classes of severity. For the remainder of the outcomes in the study (referred to as “disabling sequelae”), participants were asked to allocate a set of typical cases for a particular sequela across the seven classes. The indicator conditions within each class supplied a concrete operational definition for the average severity level in that class and thus marked points of reference on the numerical scale ranging from perfect health to death. Critics of the DALY have questioned aspects of this approach. The use of an expert panel has provoked suggestions for a more inclusive measurement exercise to represent the broader perspectives of communities and societies.4 Other researchers have asked whether there may be important variation in assessments of health outcomes across diverse cultures and environments,6,8,9 indicating a need for more cross-country measurement and comparison. Some critics have opposed, on ethical grounds, the use of the person trade-off technique as implemented in the 1996 group exercise.5 Over the past two years, with support from the Bill & Melinda Gates Foundation, a research consortium including the Institute for Health Metrics and Evaluation, Harvard University, Johns Hopkins University, University of Queensland and the World Health Organization has been leading a major revision of the global burden of disease, in collaboration with a network of hundreds of experts from around the world. An essential element in this study is a comprehensive re-estimation of disability weights for the full set of around 230 unique sequelae associated with the array of disease and injury causes in the study. The design of this new study responds to critiques of past efforts in several significant ways. With two major components of survey-based data collection, the new study uses simple paired-comparison questions. In these questions, respondents are asked to consider two hypothetical individuals characterized by different functional limitations, and to indicate which person they would regard as healthier. These simple questions permit input from a broad cross-section of respondents spanning diverse cultural, environmental and demographic circumstances. Straightforward analytic approaches allow inferences about cardinal weights at the population-level based on ordinal responses by individuals.10 The first component of the study comprises new population-based household surveys in six countries (Bangladesh, Indonesia, Peru, South Africa, the United Republic of Tanzania and the United States of America). Data from these surveys will deliver welcome empirical evidence on questions regarding the extent of variation in health assessments across different settings. The second component uses an open-access, internet-based survey, which is intended to expand its global reach. Presently available in English, eventual translation of the survey into other languages will further broaden participation. Design overlap with the household survey will allow direct comparison and evaluation of possible selection effects due to non-random sampling, while the web-based format and unrestricted access allow broader input from voices that are seldom heard in discussions on global health priorities. Reliable, valid and comparable measurement of non-fatal health outcomes is as essential as accurate measurement of mortality and causes of death in assessing the health of populations. Persistent challenges to existing disability weights demand further empirical study through data collection efforts that are broad-reaching and inclusive. This time around, everybody is invited to make his or her view count by participating in the online disability weights measurement survey
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Earlier estimates of skin disease prevalence and health impact used flawed epidemiological studies, analytical methods, and disability weighting.
“Previous attempts have been made to estimate the prevalence and health impact of skin diseases (Murray and Lopez, 1996;Global Burden of Disease, 2008) but these have relied on epidemiological studies, analytical methods, and disability weighting, which had flaws (Salomon, 2010).”
From The Global Burden of Skin Disease in 2010: An Analysis of the Prevalence and Impact of Skin Conditions (2014) · cites this paper as Salomon, 2010
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- Authors
- Salomon, J.
- Affiliations
- Harvard University (US)
- Corresponding author
- Salomon, Joshua
- ORCID
- Salomon, Joshua
- Venue
- Bulletin of the World Health Organization
- Publisher
- WHO Press
- Published
- 2010-12-01
- Volume
- 88
- Issue
- 12
- Pages
- 879-879
- ISSN
- 0042-9686 (ISSN-L)
- PMC
- PMC2995197
- OpenAlex
- W2079447795
- Cited by
- 62
- References
- 11
- Citations by year
- 2026: 1 · 2024: 4 · 2023: 3 · 2022: 2 · 2021: 5 · 2020: 2 · 2019: 4 · 2018: 3 · 2017: 5 · 2016: 8 · 2015: 5 · 2014: 5 · 2013: 5 · 2012: 9
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- other-oa
- Locations
- Bulletin of the World Health Organization (publishedVersion, other-oa)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
- Topics
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Medical Practices and Rehabilitation
- Keywords
- disability weights, disability-adjusted life years, global burden of disease, person trade-off, health outcome measurement, cross-cultural validity, healthcare workers, health system governance
- MeSH terms
- Persons with Disabilities, Humans, Global Health, Cost of Illness
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