The DOI matches its Crossref record; 143 of the 143 references it cites were found in a registry or an index.
Role of Inflammation in Atherosclerosis
Open accessAbstract
Inflammation plays a major role in all phases of atherosclerosis. Stable plaques are characterized by a chronic inflammatory infiltrate, whereas vulnerable and ruptured plaques are characterized by an "active" inflammation involved in the thinning of the fibrous cap, predisposing the plaque to rupture. Although a single vulnerable atherosclerotic plaque rupture may cause the event, there are many other types of plaques, several of which are vulnerable. The existence of multiple types of vulnerable plaques suggests that atherosclerosis is a diffuse inflammatory process. A current challenge is to identify morphologic and molecular markers able to discriminate stable plaques from vulnerable ones, allowing the stratification of patients at high risk for acute cardiovascular and cerebrovascular events before clinical syndromes develop. With that aim in mind, this article summarizes the natural history of atherosclerotic plaques, focusing on molecular mechanisms affecting plaque progression and serum markers correlated with plaque inflammation.
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Cites
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Hansson, G. K. (2005) · New England Journal of Medicine · doi:10.1056/nejmra043430 · Cited by 8,773
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Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men
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Cited by
Omega-6 fats for the primary and secondary prevention of cardiovascular disease
Hooper, L., Al-Khudairy, L., Abdelhamid, A. S., Rees, K., Brainard, J. S., Brown, T. J., Ajabnoor, S. M., O'Brien, A. T., Winstanley, L. E., Donaldson, D. H., et al. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011094.pub4 · Cited by 133
Metadata
- Authors
- Spagnoli, L. G., Bonanno, E., Sangiorgi, G., & Mauriello, A.
- Venue
- Journal of Nuclear Medicine
- Publisher
- Society of Nuclear Medicine
- Published
- 2007-11-01
- Volume
- 48
- Issue
- 11
- Pages
- 1800-1815
- ISSN
- 0161-5505 (ISSN-L)
- OpenAlex
- W2142563319
- Cited by
- 293
- References
- 143
- FWCI
- 4.50
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Spagnoli, L. G., Bonanno, E., Sangiorgi, G., & Mauriello, A. (2007). Role of Inflammation in Atherosclerosis. Journal of Nuclear Medicine. https://doi.org/10.2967/jnumed.107.038661
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
