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Optical Imaging: Current Applications and Future Directions
Open accessAbstract
Optical techniques, such as bioluminescence and fluorescence, are emerging as powerful new modalities for molecular imaging in disease and therapy. Combining innovative molecular biology and chemistry, researchers have developed optical methods for imaging a variety of cellular and molecular processes in vivo, including protein interactions, protein degradation, and protease activity. Whereas optical imaging has been used primarily for research in small-animal models, there are several areas in which optical molecular imaging will translate to clinical medicine. In this review, we summarize recent advances in optical techniques for molecular imaging and the potential impact for clinical medicine.
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Cited by
van Dam, G. M., Themelis, G., Crane, L. M. A., Harlaar, N. J., Pleijhuis, R. G., Kelder, W., Sarantopoulos, A., de Jong, J. S., Arts, H. J. G., van der Zee, A. G. J., et al. (2011) · Nature Medicine · doi:10.1038/nm.2472 · Cited by 1,545
Quantum Dots and Their Multimodal Applications: A Review
Bera, D., Qian, L., Tseng, T.-K., & Holloway, P. H. (2010) · Materials · doi:10.3390/ma3042260 · Cited by 1,365
Multimodality Imaging Probes: Design and Challenges
Louie, A. (2010) · Chemical Reviews · doi:10.1021/cr9003538 · Cited by 1,044
Ratiometric optical nanoprobes enable accurate molecular detection and imaging
Huang, X., Song, J., Yung, B. C., Huang, X., Xiong, Y., & Chen, X. (2018) · Chemical Society Reviews · doi:10.1039/c7cs00612h · Cited by 820
Wang, J., & Dong, J. (2020) · Sensors · doi:10.3390/s20143981 · Cited by 77
Metadata
- Authors
- Luker, G. D., & Luker, K. E.
- Venue
- Journal of Nuclear Medicine
- Publisher
- Society of Nuclear Medicine
- Published
- 2007-12-12
- Volume
- 49
- Issue
- 1
- Pages
- 1-4
- ISSN
- 0161-5505 (ISSN-L)
- 2159-662X
- OpenAlex
- W2160158310
- Cited by
- 404
- References
- 0
- FWCI
- 12.77
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Luker, G. D., & Luker, K. E. (2008). Optical Imaging: Current Applications and Future Directions. Journal of Nuclear Medicine. https://doi.org/10.2967/jnumed.107.045799
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