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Molecular Detection and Serotyping of Streptococcus pneumoniae in Children with Suspected Meningitis in Northeast Iran.
Open accessAbstract
BACKGROUND: in developing countries, serotyping of the prevalent isolates is useful in selecting the correct vaccine. The present study aimed to evaluate common serotypes of pneumococcal meningitis in Bojnurd, Iran. METHODS: . In addition, the modified Marimon's PCR method was used for serotyping the bacteria. The data were analyzed using Pearson's Chi-square test. RESULTS: using the PCR method, while only 92 cases tested positive using the conventional methods. Based on the Marimon's PCR method, serotypes 23F, 19F, 19A, 1, 14, and serogroup 6A/B were the most common types. Serogroups 18C, 15A/F, 15B/C, 9A/V, 7A/F, 11A/D/F, and 22A/F were also detected in isolates. Note that 2.8% of the samples were non-typable (NT). CONCLUSION: International Congress of Microbiology, as a poster and published in the congress abstracts book.
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“The reported sensitivity of PCR for pneumococcal meningitis is high and reached 100% in the majority of conducted studies (median of 100%, range 79%–100%) (Table 1; see also Table S1 in the supplemental material) (49–58).”
From Molecular diagnostics in cerebrospinal fluid for the diagnosis of central nervous system infections (2024) · cites this paper as [49]
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Cited by
Molecular diagnostics in cerebrospinal fluid for the diagnosis of central nervous system infections
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Metadata
- Authors
- Abdoli, S., Safamanesh, S., Khosrojerdi, M., & Azimian, A.
- Affiliations
- North Khorasan University of Medical Sciences (IR)
- Semnan University of Medical Sciences (IR)
- ORCID
- Amir Azimian
- Venue
- PubMed Central
- Publisher
- National Institutes of Health
- Published
- 2020-03-01
- Volume
- 45
- Issue
- 2
- Pages
- 125-133
- PMC
- PMC7071549
- OpenAlex
- W2972288738
- Cited by
- 10
- References
- 30
- Citations by year
- 2025: 1 · 2024: 4 · 2023: 2 · 2022: 1 · 2021: 2
- FWCI
- 0.90
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- cc-by-nd
- Locations
- PubMed Central (publishedVersion, cc-by-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Epidemiology › Pneumonia and Respiratory Infections
- Life Sciences › Immunology and Microbiology › Microbiology › Bacterial Infections and Vaccines
- Health Sciences › Medicine › Microbiology (medical) › Bacterial Identification and Susceptibility Testing
- Keywords
- Streptococcus pneumoniae, pneumococcal meningitis, serotyping, serogroups, molecular detection, vaccine selection, children, Bojnurd
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