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Cited by 30Nutrition and Health in AgingCardiovascular and exercise physiologyPhysical Activity and Health

Effects of Circuit Training Program on Cardiovascular Risk Factors, Vascular Inflammatory Markers, and Insulin-like Growth Factor-1 in Elderly Obese Women with Sarcopenia

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Jung, Won-Sang, Kim, Yae-Young, Kim, Jeong-Weon, Park, Hun-Young·2022·Reviews in Cardiovascular Medicine
DOI 10.31083/j.rcm2304134PMC PMC11273982
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Abstract

Background: Sarcopenic obesity is caused by a decrease in muscle mass and an increase in body fat due to aging, and has been the cause of cardiovascular diseases such as hypertension, diabetes, hyperlipidemia, and arteriosclerosis and high inflammatory conditions. However, there is a lack of research on the effects of long-term exercise training as regards to the body composition and blood-related physiological indicators. Therefore, the purpose of this study was to investigate the influences the effect of circuit exercise training for 12 weeks on cardiovascular risk factors, vascular inflammatory markers, and insulin-like growth factor-1 (IGF-1) in elderly obesity women with sarcopenia. Methods: A total of 28 elderly obese Korean women with sarcopenia (75.0 ± 5.1 years) were randomly assigned either to a control group (CG, n = 14) or an exercise group (EG, n = 14). The EG performed circuit exercise training for 25–75 minutes (gradually incremental) three times per week over a period of 12 weeks, while the CG maintained their usual daily lifestyle during the intervention period. Pre- and post-intervention evaluations were performed on selected cardiovascular risk factors, inflammatory markers, and IGF-1. Results: The EG group exhibited improved body composition (i.e., body mass index, fat-free mass, % fat mass, waist-to-hip ratio; all p < 0.030, η2 > 0.169), Cardiovascular risks factor (i.e., heart rate, systolic blood pressure, rate pressure product, high-density lipoprotein cholesterol, total cholesterol/HDL-C ratio, triglyceride/HDL-C ratio, low-density lipoprotein cholesterol/HDL-C ratio, brachial-ankle pulse wave velocity, fasting plasma insulin, homeostasis model assessment-insulin resistance; all p < 0.042, η2 > 0.150), Inflammatory markers (i.e., high sensitivity C-reactive protein, interleukin-6; all p < 0.045, η2 > 0.146), and IGF-1 (p = 0.037, η2 = 0.157). Conversely, there were no significant changes observed in CG. Conclusions: Twelve weeks of circuit training had a positive effect on the improvement in cardiovascular risk factors, vascular inflammatory markers, and IGF-1 in elderly obese women with sarcopenia.

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  • Power training (PT) was effective in reducing body fat percentage (BF%) and visceral fat (VF) in older women with sarcopenic obesity.

    “In terms of adiposity-related variables, PT was also effective in reducing BF% and VF, consistent with previous trials [27,34,35,36].”

    From Efficacy of Power Training on Sarcopenic Obesity in Community-Dwelling Older Women: A 32-Week Randomized Clinical Trial (2025) · cites this paper as [36]

    The Discussion reports a significant reduction in percentage body fat among elderly women with sarcopenic obesity. However, Methods §2.2 identifies the intervention as circuit training, not power training, and Methods §2.3 measures waist-to-hip ratio rather than visceral fat. Page numbers are unavailable in our copy. (LLM, conf=0.88)

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Authors
Jung, W.-S., Kim, Y.-Y., Kim, J.-W., & Park, H.-Y.
Affiliations
  • Konkuk University (KR)
  • Daegu Haany University (KR)
  • Gachon University (KR)
Corresponding author
Park, Hun-Young
ORCID
Venue
Reviews in Cardiovascular Medicine
Publisher
IMR Press
Published
2022-04-08
Volume
23
Issue
4
Pages
134-134
ISSN
  • 1530-6550 (ISSN-L)
  • 2153-8174
DOI
10.31083/j.rcm2304134
PMC
PMC11273982
OpenAlex
W4223981108
Cited by
30
References
12
Citations by year
2026: 7 · 2025: 17 · 2024: 4 · 2023: 2
Type
dissertation
Language
en
Open access
Licence
Locations
  • Reviews in Cardiovascular Medicine (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • National Research Foundation
  • Konkuk University
  • National Research Foundation of Korea (NRF-2020R1G1A1101545)
  • Ministry of Science and ICT, South Korea
Topics
  • Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
Keywords
sarcopenic obesity, circuit training, older women, cardiovascular risk factors, vascular inflammation, insulin-like growth factor I, body composition, insulin resistance, C-reactive protein, interleukin-6, pulse wave velocity, lipid profile, exercise training, sarcopenia, obesity, aging, hypertension, dyslipidemia, diabetes mellitus, arteriosclerosis, body mass index, fat-free mass

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