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Investigating quality of life and health-related quality of life in infertility: a systematic review
Abstract
OBJECTIVE: To review the findings on quality of life (QOL) and health-related quality of life (HRQOL) among infertile women, men and couples. DESIGN: Systematic review. METHODS: Publications between January 1980 and July 2009 in Medline, PsycInfo, Embase and Health and Psychosocial Instruments were compiled using the following inclusion criteria: papers published in peer-reviewed journals; written in English, French, Spanish or Portuguese; presented original findings; assessed quality of life or health-related quality of life as an outcome; included infertile subjects without other clinical conditions; used validated measures. INTERVENTIONS: None. MAIN OUTCOME MEASURES: Quality of life and health-related quality of life. RESULTS: Fourteen studies were included in the review. Educational level, will to have children, poor marital relationship, previous in-vitro fertilisation attempt and duration of the infertility were predictors of lower mental health scores in infertile men. Women had significant lower scores on mental health, social functioning and emotional behaviour. Among infertile subjects, women had lower scores in several QOL or HRQOL domains in comparison to men. CONCLUSIONS: Evidences indicate important QOL or HRQOL impairments in infertile women. Among men, it does not appear to be intense. There is scarce knowledge regarding the impact of infertility on couples.
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“As in the study of Monga etal. (2004), in a systematic review conducted by Chachamovich etal. (2010) women were found to consistently reveal lower quality of life when compared to men or individuals from the general population.”
From Mapping acceptance and commitment therapy outcomes in the context of infertility: a systematic review (2024) · cites this paper as Chachamovich et al. (2010)
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Metadata
- Authors
- Chachamovich, J. R., Chachamovich, E., Ezer, H., Fleck, M. P., Knauth, D., & Passos, E. P.
- Affiliations
- Douglas Mental Health University Institute (CA)
- McGill University (CA)
- Universidade Federal do Rio Grande do Sul (BR)
- Venue
- Journal of Psychosomatic Obstetrics & Gynecology
- Publisher
- Informa UK Limited
- Published
- 2010-05-05
- Volume
- 31
- Issue
- 2
- Pages
- 101-110
- ISSN
- 0167-482X (ISSN-L)
- 1743-8942
- OpenAlex
- W2080190324
- Cited by
- 372
- References
- 53
- Citations by year
- 2026: 11 · 2025: 19 · 2024: 19 · 2023: 35 · 2022: 30 · 2021: 27 · 2020: 38 · 2019: 37 · 2018: 23 · 2017: 27 · 2016: 31 · 2015: 17 · 2014: 20 · 2013: 18 · 2012: 15
- FWCI
- 1.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychosomatic Obstetrics & Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Social Sciences › Psychology › Clinical Psychology › Health and Well-being Studies
- Keywords
- infertility, quality of life, health-related quality of life, infertile couples, infertile women, infertile men, mental health, social functioning, emotional behavior, predictors of quality of life, in vitro fertilization, infertility duration, marital relationships, educational attainment, desire for children
- MeSH terms
- Adaptation, Psychological, Adult, Attitude to Health, Depression, Emotions, Female, Fertilization in Vitro, Gender Identity, Humans, Infertility, Female, Infertility, Male, Interpersonal Relations, Male, Personality Inventory, Quality of Life, Young Adult
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