The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Investigating quality of life and health-related quality of life in infertility: a systematic review
Abstract
OBJECTIVE: To review the findings on quality of life (QOL) and health-related quality of life (HRQOL) among infertile women, men and couples. DESIGN: Systematic review. METHODS: Publications between January 1980 and July 2009 in Medline, PsycInfo, Embase and Health and Psychosocial Instruments were compiled using the following inclusion criteria: papers published in peer-reviewed journals; written in English, French, Spanish or Portuguese; presented original findings; assessed quality of life or health-related quality of life as an outcome; included infertile subjects without other clinical conditions; used validated measures. INTERVENTIONS: None. MAIN OUTCOME MEASURES: Quality of life and health-related quality of life. RESULTS: Fourteen studies were included in the review. Educational level, will to have children, poor marital relationship, previous in-vitro fertilisation attempt and duration of the infertility were predictors of lower mental health scores in infertile men. Women had significant lower scores on mental health, social functioning and emotional behaviour. Among infertile subjects, women had lower scores in several QOL or HRQOL domains in comparison to men. CONCLUSIONS: Evidences indicate important QOL or HRQOL impairments in infertile women. Among men, it does not appear to be intense. There is scarce knowledge regarding the impact of infertility on couples.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“As in the study of Monga etal. (2004), in a systematic review conducted by Chachamovich etal. (2010) women were found to consistently reveal lower quality of life when compared to men or individuals from the general population.”
From Mapping acceptance and commitment therapy outcomes in the context of infertility: a systematic review (2024) · cites this paper as Chachamovich et al. (2010)
Citations
Cites
Health Measurement Scales: A Practical Guide to Their Development and Use
Streiner, D. L., Norman, G. R., & Cairney, J. (1989) · Cited by 9,595
(1995) · Social Science & Medicine · doi:10.1016/0277-9536(95)00112-k · Cited by 7,643
Moher, D., Cook, D. J., Eastwood, S., Olkin, I., Rennie, D., & Stroup, D. F. (1999) · The Lancet · doi:10.1016/s0140-6736(99)04149-5 · Cited by 4,826
Streiner, D. L., & Norman, G. R. (2008) · doi:10.1093/acprof:oso/9780199231881.001.0001 · Cited by 2,631
A Critical Appraisal of the Quality of Quality-of-Life Measurements
Gill, T. M. (1994) · JAMA · doi:10.1001/jama.1994.03520080061045 · Cited by 2,209
A Psychometric Toolbox for Testing Validity and Reliability
DeVon, H. A., Block, M. E., Moyle‐Wright, P., Ernst, D. M., Hayden, S. J., Lazzara, D. J., Savoy, S. M., & Kostas‐Polston, E. (2007) · Journal of Nursing Scholarship · doi:10.1111/j.1547-5069.2007.00161.x · Cited by 1,889
Psychological impact of infertility
Cousineau, T. M., & Domar, A. D. (2007) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2006.12.003 · Cited by 997
Using quality of life measures in the clinical setting
Higginson, I. J., & Carr, A. J. (2001) · BMJ · doi:10.1136/bmj.322.7297.1297 · Cited by 982
Marshall, M., Lockwood, A., Bradley, C., Adams, C., Joy, C., & Fenton, M. (2000) · British Journal of Psychiatry · doi:10.1192/bjp.176.3.249 · Cited by 870 · cited 1×
“Furthermore, results based on non-validated scales are more prone to demonstrate medication efficacy [31], and inconsistent instruments are associated to biased outcome measurements in clinical trials [32].”
BackgroundInfertility and the provision of infertility medical services in developing countries
Ombelet, W., Cooke, I., Dyer, S., Serour, G., & Devroey, P. (2008) · Human Reproduction Update · doi:10.1093/humupd/dmn042 · Cited by 720
Evers, J. L. H. (2002) · The Lancet · doi:10.1016/s0140-6736(02)09417-5 · Cited by 607
Impact of infertility on quality of life, marital adjustment, and sexual function
Monga, M., Alexandrescu, B., Katz, S. E., Stein, M. B., & Ganiats, T. G. (2004) · Urology · doi:10.1016/j.urology.2003.09.015 · Cited by 506
Recommendations for Evaluating the Validity of Quality of Life Claims for Labeling and Promotion
Leidy, N. K., Revicki, D. A., & Genesté, B. (1999) · Value in Health · doi:10.1046/j.1524-4733.1999.02210.x · Cited by 387
International disparities in access to infertility services
Nachtigall, R. D. (2006) · Fertility and Sterility · doi:10.1016/j.fertnstert.2005.08.066 · Cited by 347
Reporting on quality of life in randomised controlled trials: bibliographic study
Sanders, C., Egger, M., Donovan, J., Tallon, D., & Frankel, S. (1998) · BMJ · doi:10.1136/bmj.317.7167.1191 · Cited by 304
Valderas, J. M., & Alonso, J. (2008) · Quality of Life Research · doi:10.1007/s11136-008-9396-4 · Cited by 301
Quality of Life with Defibrillator Therapy or Amiodarone in Heart Failure
Mark, D. B., Anstrom, K. J., Sun, J. L., Clapp-Channing, N. E., Tsiatis, A. A., Davidson-Ray, L., Lee, K. L., & Bardy, G. H. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0706719 · Cited by 260
Chachamovich, E., Fleck, M. P., Laidlaw, K., & Power, M. (2008) · The Gerontologist · doi:10.1093/geront/48.5.593 · Cited by 255
Self-citationDevelopment of EMPRO: A Tool for the Standardized Assessment of Patient-Reported Outcome Measures
Valderas, J. M., Ferrer, M., Mendívil, J., Garín, O., Rajmil, L., Herdman, M., & Alonso, J. (2008) · Value in Health · doi:10.1111/j.1524-4733.2007.00309.x · Cited by 234
Wiklund, I. E. (2004) · Fundamental and Clinical Pharmacology · doi:10.1111/j.1472-8206.2004.00234.x · Cited by 216
Nelson, C. J., Shindel, A. W., Naughton, C. K., Ohebshalom, M., & Mulhall, J. P. (2008) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2008.00880.x · Cited by 194
Dyer, S., Lombard, C. J., & van der Spuy, Z. M. (2009) · Human Reproduction · doi:10.1093/humrep/dep278 · Cited by 179
Shindel, A. W., Nelson, C. J., Naughton, C. K., Ohebshalom, M., & Mulhall, J. P. (2008) · The Journal of Urology · doi:10.1016/j.juro.2007.10.069 · Cited by 170
Quality of life in mental disorders: challenges for research and clinical practice.
Katschnig, H. (2006) · Europe PMC (PubMed Central) · Cited by 166
Goldney, R. D., Fisher, L. J., Dal Grande, E., & Taylor, A. W. (2004) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-004-0745-5 · Cited by 161
Charman, C. R., Chambers, C., & Williams, H. C. (2003) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2003.12251.x · Cited by 159
Schmid, J., Kirchengast, S., Vytiska-Binstorfer, E., & Huber, J. (2004) · Human Reproduction · doi:10.1093/humrep/deh432 · Cited by 152 · cited 1×
“Comparisons to normative data consensually showed that infertile women have significant lower scores on mental health, social functioning, role emotional and emotional behaviour [27,28,41,42].”
BackgroundDyer, S., Abrahams, N., Mokoena, N. E., Lombard, C. J., & van der Spuy, Z. M. (2005) · Human Reproduction · doi:10.1093/humrep/deh845 · Cited by 151
"Quality of life": a brand new concept for research and practice in psychiatry
Berlim, M. T., & Fleck, M. P. (2003) · Brazilian Journal of Psychiatry · doi:10.1590/s1516-44462003000400013 · Cited by 149
Self-citationBenyamini, Y., Gozlan, M., & Kokia, E. S. (2008) · British Journal of Health Psychology · doi:10.1348/135910708x279288 · Cited by 139
Quality of life and sexual functioning of Polish infertile couples
Drosdzol, A., & Skrzypulec, V. (2008) · The European Journal of Contraception & Reproductive Health Care · doi:10.1080/13625180802049187 · Cited by 133
Health-related quality of life in infertile couples receiving IVF or ICSI treatment
Rashidi, B. H., Montazeri, A., Ramezanzadeh, F., Shariat, M., Abedinia, N., & Ashrafi, M. (2008) · BMC Health Services Research · doi:10.1186/1472-6963-8-186 · Cited by 133
Psychological implications of infertility in women with polycystic ovary syndrome
Tan, S., Hahn, S., Benson, S., Janssen, O. E., Dietz, T., Kimmig, R., Hesse-Hussain, J., Mann, K., Schedlowski, M., Arck, P. C., et al. (2008) · Human Reproduction · doi:10.1093/humrep/den227 · Cited by 128
Health-related quality of life in relation to gender and age in couples planning IVF treatment
Fekkes, M. (2003) · Human Reproduction · doi:10.1093/humrep/deg276 · Cited by 128
Evaluation of Sexual Dysfunction Prevalence in Infertile Couples
Khademi, A., Alleyassin, A., Amini, M., & Ghaemi, M. (2008) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2007.00687.x · Cited by 123
Congruence of quality of life among infertile men and women: findings from a couple-based study
Chachamovich, J. L. R., Chachamovich, E., Fleck, M. P. D. A., Córdova, F. P., Knauth, D. R., & Passos, E. P. (2009) · Human Reproduction · doi:10.1093/humrep/dep177 · Cited by 117
Self-citationHealth‐related quality of life measurement
Sajid, M. S., Tonsi, A., & Baig, M. K. (2008) · International Journal of Health Care Quality Assurance · doi:10.1108/09526860810880162 · Cited by 103
Health-related quality of life and need for IVF in 1000 Italian infertile couples
Ragni, G., Mosconi, P., Baldini, M. P., Somigliana, E., Vegetti, W., Caliari, I., & Nicolosi, A. E. (2005) · Human Reproduction · doi:10.1093/humrep/deh788 · Cited by 96
Subsyndromal depression: An impact on quality of life?
Lima, A. F. B. D. S., & Fleck, M. P. D. A. (2006) · Journal of Affective Disorders · doi:10.1016/j.jad.2006.10.010 · Cited by 93
Self-citationImplications of psychosocial support in infertility – a critical appraisal
Wischmann, T. H. (2008) · Journal of Psychosomatic Obstetrics & Gynecology · doi:10.1080/01674820701817870 · Cited by 85
Effects of a psychological intervention on depression in infertile couples
Noorbala, A. A., Ramazanzadeh, F., Malekafzali, H., Abedinia, N., Forooshani, A. R., Shariat, M., & Jafarabadi, M. N. (2008) · International Journal of Gynecology & Obstetrics · doi:10.1016/j.ijgo.2007.12.010 · Cited by 84
Bezjak, A., Lee, C. W., Ding, K., Brundage, M., Winton, T. L., Graham, B., Whitehead, M., Johnson, D. H., Livingston, R. B., Seymour, L., et al. (2008) · Journal of Clinical Oncology · doi:10.1200/jco.2007.12.6094 · Cited by 78
Coëffin-Driol, C., & Giami, A. (2004) · Gynécologie Obstétrique & Fertilité · doi:10.1016/j.gyobfe.2004.06.004 · Cited by 76
Factors influencing the quality of life of infertile women in United Arab Emirates
Khayata, G. M., Rizk, D. E. E., Hasan, M. Y., Ghazal‐Aswad, S., & Asaad, M. A. N. (2003) · International Journal of Gynecology & Obstetrics · doi:10.1016/s0020-7292(02)00387-9 · Cited by 74
Chachamovich, J. L. R., Chachamovich, E., Záchia, S. D. A., Knauth, D. R., & Passos, E. P. (2007) · Human Reproduction · doi:10.1093/humrep/dem080 · Cited by 73
Self-citationLau, J. T. F., Wang, Q., Cheng, Y., Kim, J. H., Yang, X., & Tsui, H. Y. (2008) · Journal of Sex & Marital Therapy · doi:10.1080/00926230701866117 · Cited by 65
Quality of life for couples 4–5.5 years after unsuccessful IVF treatment
Johansson, M., Adolfsson, A., Berg, M., Francis, J., Hogström, L., Janson, P. O., Sogn, J., & Hellström, A. (2009) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1080/00016340802705956 · Cited by 50
Psychosocial Predictors of Life Quality
Abbey, A., Andrews, F. M., & Halman, L. J. (1994) · Journal of Family Issues · doi:10.1177/0192513x94015002006 · Cited by 48
Survey of Psychological Health in Women with Infertility
Souter, V. L., Hopton, J., Penney, G., & Templeton, A. A. (2002) · Journal of Psychosomatic Obstetrics & Gynecology · doi:10.3109/01674820209093414 · Cited by 46
A new quality-of-life measure for men experiencing involuntary childlessness
Schanz, S., Bäckert-Sifeddine, I.-T., Braeunlich, C., Collins, S. E., Batra, A., Gebert, S., Hautzinger, M., & Fierlbeck, G. (2005) · Human Reproduction · doi:10.1093/humrep/dei127 · Cited by 36
Quality of life and its correlates among a group of infertile Iranian women.
Aliyeh, G., & Laya, F. (2007) · PubMed · Cited by 31
Current Reproductive Technologies: Increased Access and Choice?
Beckman, L. J., & Harvey, S. M. (2005) · Journal of Social Issues · doi:10.1111/j.0022-4537.2005.00391.x · Cited by 29
Effects of Repeated Treatment Failure on the Quality of Life of Couples with Infertility
El‐Messidi, A., Al-Fozan, H. M., Tan, S. L., Farag, R., & Tulandi, R. (2004) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/s1701-2163(16)30361-9 · Cited by 24
Research works printed but not linked: 6
- WHO, 2003, Progr Reprod Health Res, 1
- Katschnig H, 2006, World Psychiatry, 5, 139
- Aliyeh G, 2007, Med Sci Monit, 13, CR313
- Patrick DL, Erickson P. Health status and health police. Oxford: Oxford University Press; 1993.
- 1995, Soc Sci Med, 41, 1403, 10.1016/0277-9536(95)00112-K · DOI · Paper page
- Moher D, 1999, Quality of Reporting of Meta-analyses. Lancet, 354, 1896
Cited by
Sorted by citations
Mascarenhas, M., Flaxman, S. R., Boerma, T., Vanderpoel, S., & Stevens, G. A. (2012) · PLoS Medicine · doi:10.1371/journal.pmed.1001356 · Cited by 2,357
Eisenberg, M. L., Esteves, S. C., Lamb, D. J., Hotaling, J. M., Giwercman, A., Hwang, K., & Cheng, Y.-S. (2023) · Nature Reviews Disease Primers · doi:10.1038/s41572-023-00459-w · Cited by 536
Luk, B. H.-K., & Loke, A. Y. (2014) · Journal of Sex & Marital Therapy · doi:10.1080/0092623x.2014.958789 · Cited by 349
Black, R. E., Levin, C., Walker, N., Chou, D., Liu, L., & Temmerman, M. (2016) · The Lancet · doi:10.1016/s0140-6736(16)00738-8 · Cited by 241
Fisher, J., & Hammarberg, K. (2011) · Asian Journal of Andrology · doi:10.1038/aja.2011.72 · Cited by 242
Metadata
- Authors
- Chachamovich, J. R., Chachamovich, E., Ezer, H., Fleck, M. P., Knauth, D., & Passos, E. P.
- Affiliations
- Douglas Mental Health University Institute (CA)
- McGill University (CA)
- Universidade Federal do Rio Grande do Sul (BR)
- Venue
- Journal of Psychosomatic Obstetrics & Gynecology
- Publisher
- Informa UK Limited
- Published
- 2010-05-05
- Volume
- 31
- Issue
- 2
- Pages
- 101-110
- ISSN
- 0167-482X (ISSN-L)
- 1743-8942
- OpenAlex
- W2080190324
- Cited by
- 372
- References
- 53
- Citations by year
- 2026: 11 · 2025: 19 · 2024: 19 · 2023: 35 · 2022: 30 · 2021: 27 · 2020: 38 · 2019: 37 · 2018: 23 · 2017: 27 · 2016: 31 · 2015: 17 · 2014: 20 · 2013: 18 · 2012: 15
- FWCI
- 1.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychosomatic Obstetrics & Gynecology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Social Sciences › Psychology › Clinical Psychology › Health and Well-being Studies
- Keywords
- infertility, quality of life, health-related quality of life, infertile couples, infertile women, infertile men, mental health, social functioning, emotional behavior, predictors of quality of life, in vitro fertilization, infertility duration, marital relationships, educational attainment, desire for children
- MeSH terms
- Adaptation, Psychological, Adult, Attitude to Health, Depression, Emotions, Female, Fertilization in Vitro, Gender Identity, Humans, Infertility, Female, Infertility, Male, Interpersonal Relations, Male, Personality Inventory, Quality of Life, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
