Cited by 81Heart Rate Variability and Autonomic ControlRheumatoid Arthritis Research and TherapiesCardiovascular Syncope and Autonomic Disorders

Autonomic nerve function in rheumatoid arthritis of varying severity

Leden, Ido, Eriksson, Anita, Lilja, Bo, Sturfelt, Gunnar, Sundkvist, Goran·1983·Scandinavian Journal of Rheumatology

Abstract

Autonomic nerve function was evaluated by deep breathing and tilt table tests in 17 patients with rheumatoid arthritis (RA) and in 24 healthy control subjects. The results showed that all RA patients had increased heart rates at rest, irrespective of the severity of the disease. Patients with severe RA had increased systolic and diastolic blood pressures before and after tilting. Pronounced abnormalities in the immediate heart rate reaction to tilting indicating autonomic neuropathy (AN) were also demonstrated in patients with severe RA. The abnormal immediate reaction to tilting was mainly the result of vagal neuropathy. From the present study it is evident that severe RA may be accompanied by AN and the consequences need to be elucidated.

Integrity signals

Registry

Crossref · 10.3109/03009748309102905

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17 of 17 references verified0 citation errors · 0 not checkable

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Authors
Leden, I., Eriksson, A., Lilja, B., Sturfelt, G., & Sundkvist, G.
Affiliations
  • Centralsjukhuset Kristianstad (SE)
  • Lund University (SE)
  • Skåne University Hospital (SE)
Venue
Scandinavian Journal of Rheumatology
Published
1983-01
Volume
12
Issue
2
Pages
166-170
ISSN
  • 0300-9742 (ISSN-L)
  • 1502-7732
OpenAlex
W2123312727
Cited by
81
References
17
Citations by year
2024: 1 · 2023: 1 · 2021: 1 · 2020: 1 · 2017: 2 · 2016: 2 · 2015: 4 · 2014: 2 · 2013: 3 · 2012: 1
FWCI
0.36
Type
journal article
Language
en
Open access
closed
Locations
  • Scandinavian Journal of Rheumatology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
  • Health Sciences › Medicine › Rheumatology › Rheumatoid Arthritis Research and Therapies
  • Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
Keywords
rheumatoid arthritis, autonomic neuropathy, autonomic nervous system activity, heart rate, blood pressure, tilt table test, deep breathing test, disease severity
MeSH terms
Adult, Aged, Antibodies, Antinuclear, Arthritis, Rheumatoid, Autonomic Nervous System, Blood Pressure, Electrocardiography, Female, Heart Rate, Humans, Male, Middle Aged, Posture, Respiration

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