Cited by 102Heart Rate Variability and Autonomic ControlVagus Nerve Stimulation ResearchPsychosomatic Disorders and Their Treatments

Altered autonomic function in patients with arthritis or with chronic myofascial pain

Perry, Franklin, Heller, Philip H., Kamiya, Joe, Levine, Jon D.·1989·Pain

Abstract

Dynamic autonomic function tests (pupillary light reflex, Valsalva maneuver, and mental arithmetic) were used to evaluate autonomic function (pupil size, heart rate, and skin conductance) in patients with inflammatory arthritis or with chronic myofascial pain. Physiological responses in both groups of patients suggest concurrent increases in tonic pupillary autonomic activity (sympathetic and parasympathetic), with a relative sympathetic dominance, and a decrease in tonic parasympathetic cardiovascular activity. Furthermore, in the arthritis group, the data suggest decreased cardiovascular parasympathetic reaction and enhanced sudomotor reaction.

Integrity signals

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Crossref · 10.1016/0304-3959(89)90177-2

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44 of 44 references verified0 citation errors · 0 not checkable

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Authors
Perry, F., Heller, P. H., Kamiya, J., & Levine, J. D.
Affiliations
University of California, San Francisco (US)
Corresponding author
Levine, Jon D.
Venue
Pain
Published
1989-10
Volume
39
Issue
1
Pages
77-84
ISSN
0304-3959 (ISSN-L)
OpenAlex
W2023050693
Cited by
102
References
44
Citations by year
2026: 1 · 2024: 3 · 2023: 6 · 2022: 3 · 2021: 1 · 2020: 5 · 2019: 1 · 2018: 5 · 2017: 2 · 2016: 4 · 2015: 4 · 2014: 1 · 2013: 4 · 2012: 2
FWCI
0.77
Type
journal article
Language
en
Open access
closed
Locations
  • Pain (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (5r01am032634-03)
  • Medical Research Council
  • National Institute of Neurological Disorders and Stroke (NS21647)
  • National Institute of Dental and Craniofacial Research (DEO5369)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
  • Life Sciences › Neuroscience › Neurology › Vagus Nerve Stimulation Research
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Keywords
autonomic function, inflammatory arthritis, chronic myofascial pain, pupillary light reflex, Valsalva maneuver, mental arithmetic, skin conductance, heart rate, sympathetic dominance, parasympathetic activity
MeSH terms
Arthritis, Autonomic Nervous System, Cardiovascular System, Chronic Disease, Galvanic Skin Response, Humans, Myofascial Pain Syndromes, Pupil

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