The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Oxidative Stress, Diabetes, and Diabetic Complications
Abstract
Oxidative stress is considered to be the main cause for several chronic diseases including diabetes. Through hyperglycemia, hyperlipidemia, hypertension and possible iron dyshomeostasis, diabetes induces oxidative stress that causes damage to multiple organs, leading to various complications. Therefore, antioxidant therapy may be an interesting approach to prevent diabetes and diabetic complications. Metallothionein as a potent antioxidant was found to significantly protect heart and kidney against diabetes-induced pathophysiological changes. Zinc as an important trace element and a metallothionein inducer was found to have same protective function. Since diabetes would impair defensive system, including growth factor reduction, exogenous supplementation of fibroblast growth factor (FGF) significantly prevented diabetes-induced cardiac oxidative damage and wound healing impairment. These studies suggest that protective agents such as metallothionein, zinc and FGFs play an important role in preventing the development of diabetes and diabetic complications.
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Cites
The FGF family: biology, pathophysiology and therapy
Beenken, A., & Mohammadi, M. (2009) · Nature Reviews Drug Discovery · doi:10.1038/nrd2792 · Cited by 1,945
Overexpression of Metallothionein Reduces Diabetic Cardiomyopathy
Liang, Q., Carlson, E. C., Donthi, R. V., Kralik, P. M., Shen, X., & Epstein, P. N. (2002) · Diabetes · doi:10.2337/diabetes.51.1.174 · Cited by 182
Li, X., Cai, L., Feng, W., Li, X., Cai, L., & Feng, W. (2007) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/138955707781024490 · Cited by 42
Self-citation
Cited by
Exercise-induced oxidative stress: Friend or foe?
Powers, S. K., Deminice, R., Ozdemir, M., Yoshihara, T., Bomkamp, M. P., & Hyatt, H. (2020) · Journal of Sport and Health Science · doi:10.1016/j.jshs.2020.04.001 · Cited by 655
Exercise-induced oxidative stress in humans: cause and consequences
Powers, S. K., Nelson, W. B., & Hudson, M. B. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.12.009 · Cited by 441
Shi, G.-J., Li, Y., Cao, Q.-H., Wu, H.-X., Tang, X.-Y., Gao, X.-H., Yu, J.-Q., Chen, Z., & Yang, Y. (2019) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.10.130 · Cited by 299
Bai, Y., Cui, W., Xin, Y., Miao, X., Barati, M. T., Zhang, C., Chen, Q., Tan, Y., Cui, T., Zheng, Y., et al. (2013) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2013.01.008 · Cited by 274
Self-citationCoenzyme Q10 supplementation: Efficacy, safety, and formulation challenges
Arenas‐Jal, M., Suñé‐Negre, J. M., & García‐Montoya, E. (2020) · Comprehensive Reviews in Food Science and Food Safety · doi:10.1111/1541-4337.12539 · Cited by 239
Metadata
- Authors
- Wei, W., Liu, Q., Tan, Y., Liu, L., Li, X., & Cai, L.
- Venue
- Hemoglobin
- Publisher
- Informa UK Limited
- Published
- 2009-10
- Volume
- 33
- Issue
- 5
- Pages
- 370-377
- ISSN
- 0363-0269 (ISSN-L)
- 1532-432X
- OpenAlex
- W2097262809
- Cited by
- 177
- References
- 3
- FWCI
- 10.10
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wei, W., Liu, Q., Tan, Y., Liu, L., Li, X., & Cai, L. (2009). Oxidative Stress, Diabetes, and Diabetic Complications. Hemoglobin. https://doi.org/10.3109/03630260903212175
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