Cited by 420Neurotransmitter Receptor Influence on BehaviorMemory and Neural MechanismsNeuroscience and Neuropharmacology Research

The DOI matches its Crossref record; 123 of the 123 references it cites were found in a registry or an index.

Role of serotonin in memory impairment.

Buhot, Marie-Christine, Martin, Stéphanie, Segu, Louis·2000·Annals of Medicine

DOI 10.3109/07853890008998828

Open this paper in CoChat — free account

Abstract

As a result of its presence in various structures of the central nervous system serotonin (5-HT) plays a role in a great variety of behaviours such as food intake, activity rythms, sexual behaviour and emotional states. Despite this lack of functional specialization, the serotonergic system plays a significant role in learning and memory, in particular by interacting with the cholinergic, glutamatergic, dopaminergic or GABAergic systems. Its action is mediated via specific receptors located in crucial brain structures involved in these functions, primarily the septo-hippocampal complex and the nucleus basalis magnocellularis (NBM)-frontal cortex. Converging evidence suggests that the administration of 5-HT2A/2C or 5-HT4 receptor agonists or 5-HT1A or 5-HT3 and 5-HT1B receptor antagonists prevents memory impairment and facilitates learning in situations involving a high cognitive demand. In contrast, antagonists for 5-HT2A/2C and 5-HT4, or agonists for 5-HT1A or 5-HT3 and 5-HT1B generally have opposite effects. A better understanding of the role played by these and other serotonin receptor subtypes in learning and memory is likely to result from the recent availability of highly specific ligands, such as 5-HT1A, 5-HT1B, 5-HT2A receptor antagonists, and new molecular tools, such as gene knock-out mice, especially inducible mice in which a specific genetic alteration can be restricted both temporally and anatomically.

Integrity signals

Registry

Crossref · 10.3109/07853890008998828

Cites

123 of 123 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Reconciling the role of central serotonin neurons in human and animal behavior
Soubrié, P. (1986) · Behavioral and Brain Sciences · doi:10.1017/s0140525x00022871 · Cited by 993
Enhanced Aggressive Behavior in Mice Lacking 5-HT 1B Receptor
Saudou, F., Amara, D. A., Dierich, A., LeMeur, M., Ramboz, S., Ségu, L., Buhot, M.-C., & Hen, R. (1994) · Science · doi:10.1126/science.8091214 · Cited by 839
Self-citation
Serotonin receptor 1A knockout: An animal model of anxiety-related disorder
Ramboz, S., Oosting, R. S., Amara, D. A., Kung, H. F., Blier, P., Mendelsohn, M. M., Mann, J. J., Brunner, D., & Hen, R. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.24.14476 · Cited by 831
Elevated anxiety and antidepressant-like responses in serotonin 5-HT 1A receptor mutant mice
Heisler, L. K., Chu, H.-M., Brennan, T. J., Danao, J. A., Bajwa, P., Parsons, L. H., & Tecott, L. H. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.25.15049 · Cited by 704
Increased anxiety of mice lacking the serotonin 1A receptor
Parks, C. L., Robinson, P. S., Sibille, E. L., Shenk, T. E., & Tóth, M. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.18.10734 · Cited by 691
The 5-HT3B subunit is a major determinant of serotonin-receptor function
Davies, P. A., Pistis, M., Hanna, M. C., Peters, J. A., Lambert, J. J., Hales, T. G., & Kirkness, E. F. (1999) · Nature · doi:10.1038/16941 · Cited by 561
Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats
Brezun, J. M., & Daszuta, A. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00693-9 · Cited by 549
The role of interactions between the cholinergic system and other neuromodulatory systems in learing and memory
Decker, M. W., & McGaugh, J. L. (1991) · Synapse · doi:10.1002/syn.890070209 · Cited by 527
Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist
Fletcher, A., Forster, E. A., Bill, D. J., Brown, G., Cliffe, I. A., Hartley, J. E., Jones, D. E., McLenachan, A. P., Stanhope, K. J., Critchley, D. J. P., et al. (1995) · Behavioural Brain Research · doi:10.1016/0166-4328(96)00118-0 · Cited by 526
The 5-HT3Receptor Is Present in Different Subpopulations of GABAergic Neurons in the Rat Telencephalon
Morales, M., & Bloom, F. E. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-09-03157.1997 · Cited by 364

Show all 123 references

Research works printed but not linked: 8

Carli M, 1998, Eur J Pharmacol, 10, 221
Harder J A, 1996, Psychopharmacology, 127, 245
Liang K C, 1998, Chin J Physiol, 41, 33
Consolo S, 1996, J Pharmacol Exp Ther, 277, 823
Malleret G, 1999, Soc Neurosci Abst, 25, 2156
Roychoudhury M, 1997, Meth Find Exp Clin Pharmacol, 19, 43
Guy N TM, 1997, Soc Neurosci Abstr, 23, 290
Stark K L, 1997, Soc Neurosci Abstr, 23, 290

Sorted by citations

Items 201–300 of 420

5-HT3a Receptors Modulate Hippocampal Gamma Oscillations by Regulating Synchrony of Parvalbumin-Positive Interneurons
Huang, Y., Yoon, K., Ko, H., Jiao, S., Ito, W., Wu, J.-Y., Yung, W.-H., Lu, B., & Morozov, A. (2014) · Cerebral Cortex · doi:10.1093/cercor/bhu209 · Cited by 27
Kinetic deterioration of short memory in rat with acute hepatic encephalopathy: Involvement of astroglial and neuronal dysfunctions
Khiat, A. E., Tamegart, L., Draoui, A., Fari, R. E., Sellami, S., Rais, H., Hiba, O. E., & Gamrani, H. (2019) · Behavioural Brain Research · doi:10.1016/j.bbr.2019.03.046 · Cited by 27
A review of the literature on neuroimaging of serotoninergic function in Alzheimer’s disease and related disorders
Salmon, É. (2007) · Journal of Neural Transmission · doi:10.1007/s00702-007-0636-5 · Cited by 27
Flumazenil and tacrine increase the effectiveness of ondansetron on scopolamine-induced impairment of spatial learning in rats
Diez-Ariza, M., Redondo, C., Garcı́a-Alloza, M., Lasheras, B., R�o, J. D., & Ram�rez, M. J. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1467-1 · Cited by 27
Emphasizing roles of BDNF promoters and inducers in Alzheimer's disease for improving impaired cognition and memory
Banerjee, M., & Shenoy, R. R. (2021) · Journal of Basic and Clinical Physiology and Pharmacology · doi:10.1515/jbcpp-2021-0182 · Cited by 29
5‐ HT 1B receptor imaging and cognition: A positron emission tomography study in control subjects and parkinson's disease patients
Varrone, A., Svenningsson, P., Marklund, P., Fatouros‐Bergman, H., Forsberg, A., Halldin, C., Nilsson, L., & Farde, L. (2015) · Synapse · doi:10.1002/syn.21823 · Cited by 27
Review on Ethanomedicinal and Pharmacological Properties of Ficus religiosa
Kaur, A., Rana, A. C., Tiwari, V., Sharma, R., & Kumar, S. (2011) · Cited by 26
Ethanol and acetaldehyde differentially alter extracellular dopamine and serotonin in Aldh2-knockout mouse dorsal striatum: A reverse microdialysis study
Jamal, M., Ameno, K., Miki, T., Tanaka, N., Ito, A., Ono, J., Takakura, A., Kumihashi, M., & Kinoshita, H. (2015) · NeuroToxicology · doi:10.1016/j.neuro.2015.12.011 · Cited by 26
Transition metal oxide based non‐enzymatic electrochemical sensors: An arising approach for the meticulous detection of neurotransmitter biomarkers
Poolakkandy, R. R., & Menamparambath, M. M. (2020) · Electrochemical Science Advances · doi:10.1002/elsa.202000024 · Cited by 28
Memory Disorders Related to Hippocampal Function: The Interest of 5-HT4Rs Targeting
Roux, C. M., Léger, M., & Fréret, T. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222112082 · Cited by 26
Effects of early serotonin programming on behavior and central monoamine concentrations in an avian model
Dennis, R. L., Lay, D. C., Jr., & Cheng, H. W. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.07.043 · Cited by 27
Effects of pre- and postnatal exposure to 5-methoxytryptamine and early handling on an object-place association learning task in adolescent rat offspring
Cannizzaro, C., Plescia, F., Gagliano, M., Cannizzaro, G., Provenzano, G., Mantia, G., & Cannizzaro, E. (2007) · Neuroscience Research · doi:10.1016/j.neures.2007.05.012 · Cited by 24
Association between triallelic polymorphism of the serotonin transporter and [18F]MPPF binding potential at 5-HT1A receptors in healthy subjects
Lothe, A., Boni, C., Costes, N., Gorwood, P. A. P. M., Bouvard, S., Bars, D. L., Lavenne, F., & Ryvlin, P. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.04.067 · Cited by 24
Chronic administration of tibolone modulates anxiety-like behavior and enhances cognitive performance in ovariectomized rats
Espinosa‐Raya, J., Neri-Gómez, T., Orozco-Suárez, S. A., Campos, M. G., & Guerra‐Araiza, C. (2011) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.10.005 · Cited by 24
Blockade of striatal 5-HT2 receptors produces retrograde amnesia in rats
Prado-Alcalá, R. A., Solana‐Figueroa, R., Galindo, L. E., Medina, A. C., & Quirarte, G. L. (2003) · Life Sciences · doi:10.1016/j.lfs.2003.06.012 · Cited by 24
Neuro-modulation, aminergic neuro-disinhibition and neuro-degeneration.
Schmitt, H. P. (2005) · Medical Hypotheses · doi:10.1016/j.mehy.2005.06.018 · Cited by 23
Delay-Dependent Working Memory Impairment in Young-Adult and Aged 5-HT1BKO Mice as Assessed in a Radial-Arm Water MazePreprint
Wolff, M., Benhassine, N., Costet, P., Hen, R., Ségu, L., & Buhot, M.-C. (2003) · Learning & Memory · doi:10.1101/lm.60103 · Cited by 23
Self-citation
The effect of immature adult-born dentate granule cells on hyponeophagial behavior is related to their roles in learning and memory
Deng, W., & Gage, F. H. (2015) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2015.00034 · Cited by 22
Neutral Sphingomyelinase is an Affective Valence-Dependent Regulator of Learning and Memory
Kalinichenko, L. S., Abdel‐Hafiz, L., Wang, A., Mühle, C., Rösel, N., Schumacher, F., Kleuser, B., Smaga, I., Frankowska, M., Filip, M., et al. (2020) · Cerebral Cortex · doi:10.1093/cercor/bhaa298 · Cited by 26
Serotonin catabolism in the central and enteric nervous systems of rats upon induction of serotonin syndrome
Squires, L. N., Talbot, K. N., Rubakhin, S. S., & Sweedler, J. V. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.04739.x · Cited by 23
Predicting targets of compounds against neurological diseases using cheminformatic methodology
Nikolic, K. M., Mavridis, L., Bautista‐Aguilera, Ó. M., Marco‐Contelles, J., Stark, H., Carreiras, M. C., Rossi, I., Massarelli, P., Agbaba, D. D., Ramsay, R. R., et al. (2014) · Journal of Computer-Aided Molecular Design · doi:10.1007/s10822-014-9816-1 · Cited by 22
Challenging the Serotonergic System in Parkinson Disease Patients
Scholtissen, B., Verhey, F. R. J., Adam, J. J., Weber, W. E. J., & Leentjens, A. F. G. (2006) · Clinical Neuropharmacology · doi:10.1097/01.wnf.0000229013.95927.c7 · Cited by 22
Sibutramine may be associated with memory impairment
Clark, D. W. J., & Harrison‐Woolrych, M. (2004) · BMJ · doi:10.1136/bmj.329.7478.1316 · Cited by 22
Oxidative and Excitatory Neurotoxic Stresses in CRISPR/Cas9-Induced Kynurenine Aminotransferase Knockout Mice: A Novel Model for Despair-Based Depression and Post-Traumatic Stress Disorder
Szabó, Á., Galla, Z., Spekker, E., Szűcs, M., Martos, D., Takeda, K., Ozaki, K., Inoue, H., Yamamoto, S., Toldi, J., et al. (2025) · Frontiers in Bioscience-Landmark · doi:10.31083/fbl25706 · Cited by 27
A Test–Retest Paradigm of the Forced Swimming Test in Female Mice Is Not Valid for Predicting Antidepressant-Like Activity: Participation of Acetylcholine and Sigma-1 Receptors
Su, J., Hato-Yamada, N., Araki, H., & Yoshimura, H. (2013) · Journal of Pharmacological Sciences · doi:10.1254/jphs.13145fp · Cited by 21
Monoaminergic Markers Across the Cognitive Spectrum of Lewy Body Disease
van der Zee, S., Vermeiren, Y., Fransén, E., Dam, D. V., Aerts, T., Gerritsen, M. J. J., Spikman, J. M., van Laar, T., & Deyn, P. P. D. (2018) · Journal of Parkinson s Disease · doi:10.3233/jpd-171228 · Cited by 21
5-Methoxy-N,N-di(iso)propyltryptamine hydrochloride (Foxy)-induced cognitive deficits in rat after exposure in adolescence
Compton, D. M., Dietrich, K. L., Selinger, M. C., & Testa, E. K. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.01.021 · Cited by 21
Quetiapine for Mania Due to Traumatic Brain Injury
Oster, T. J., Anderson, C. A., Filley, C. M., Wortzel, H. S., & Arciniegas, D. B. (2007) · CNS Spectrums · doi:10.1017/s1092852900015455 · Cited by 21
Protective effect of Carthamus tinctorius L. seed on oxidative stress and cognitive impairment induced by chronic alcohol consumption in mice
Choi, S. H., Lee, A. Y., Park, C. H., Shin, Y. S., & Cho, E. J. (2018) · Food Science and Biotechnology · doi:10.1007/s10068-018-0472-4 · Cited by 21
Transcranial ultrasound neuromodulation facilitates isoflurane-induced general anesthesia recovery and improves cognition in mice
He, J., Zhu, Y., Wu, C., Wu, J., Chen, Y., Yuan, M., Cheng, Z., Zeng, L., & Ji, X. (2023) · Ultrasonics · doi:10.1016/j.ultras.2023.107132 · Cited by 20
Serotonin depletion of supramammillary/posterior hypothalamus nuclei produces place learning deficiencies and alters the concomitant hippocampal theta activity in rats
Gutiérrez-Guzmán, B. E., Hernández-Pérez, J. J., López‐Vázquez, M. A., Soria-Fregozo, C., Guevara, M. Á., & Olvera‐Cortés, M. E. (2012) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2012.02.024 · Cited by 20
Effects of the 5-HT1B receptor antagonist NAS-181 on extracellular levels of acetylcholine, glutamate and GABA in the frontal cortex and ventral hippocampus of awake rats: A microdialysis study
Hu, X. J., Wang, F., Stenfors, C., Ögren, S. O., & Kehr, J. (2007) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2006.12.002 · Cited by 20
Application of Complementary and Alternative Medicine on Neurodegenerative Disorders: Current Status and Future Prospects
Ip, S., Tsim, K. W. K., Chan, K., & Bauer, R. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/930908 · Cited by 21
Transgenerational effects of selenomethionine on behaviour, social cognition, and the expression of genes in the serotonergic pathway in zebrafish
Attaran, A., Salahinejad, A., Naderi, M., Crane, A. L., Chivers, D. P., & Niyogi, S. (2021) · Environmental Pollution · doi:10.1016/j.envpol.2021.117289 · Cited by 19
Neural circuits expressing the serotonin 2C receptor regulate memory in mice and humans
Liu, H., He, Y., Liu, H., Brouwers, B., Yin, N., Lawler, K., Keogh, J. M., Henning, E., Lee, D.-K., Yu, M., et al. (2024) · Science Advances · doi:10.1126/sciadv.adl2675 · Cited by 20
Acute Toxicity of Organophosphorus Compounds
Morris, C. M., Savy, C. Y., Judge, S. J., & Blain, P. G. (2013) · Springer eBooks · doi:10.1007/978-1-4471-5625-3_3 · Cited by 21
Pharmacologic implications of inflammatory comorbidity in bipolar disorder
Rosenblat, J. D., Gregory, J. M., & McIntyre, R. S. (2016) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2016.06.007 · Cited by 19
Verbal memory performance during subchronic challenge with a selective serotonergic and a mixed action antidepressant
Wingen, M., Langer, S. W., & Ramaekers, J. G. (2006) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.800 · Cited by 19
Unexpected inhibitory regulation of glutamate release from rat cerebrocortical nerve terminals by presynaptic 5‐hydroxytryptamine‐2A receptors
Wang, S., Wang, K., Wang, W.-C., & Sihra, T. S. (2006) · Journal of Neuroscience Research · doi:10.1002/jnr.21060 · Cited by 19
13‐cis‐retinoic acid alters the cellular morphology of slice‐cultured serotonergic neurons in the rat
Ishikawa, J., Sutoh, C., Ishikawa, A., Kagechika, H., Hirano, H., & Nakamura, S. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06191.x · Cited by 20
Current Drug Targets in Alzheimer’s Associated Memory Impairment: A Comprehensive Review
Chandrashekar, K. S., Mathew, A., Vignesh Balaji, E., Pai, K. S. R., Kishore, A., Pai, V., & Pemmireddy, R. (2022) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/1871527321666220401124719 · Cited by 18
Hydroxy Pentacyclic Triterpene Acid, Kaempferol, Inhibits the Human 5-Hydroxytryptamine Type 3A Receptor Activity
Lee, S., Seol, H.-S., Eom, S., Lee, J., Kim, C., Park, J., Kim, T., & Lee, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23010544 · Cited by 18
ErbB4 knockdown in serotonergic neurons in the dorsal raphe induces anxiety-like behaviors
Zhang, S.-R., Wu, J., Chen, H. H., Luo, R., Chen, W., Tang, L., Li, X., Yang, J., & Gao, T. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-0601-7 · Cited by 18
Effects of a novel method of acute tryptophan depletion on plasma tryptophan and cognitive performance in healthy volunteers
Evers, E. A. T., Tillie, D. E., van der Veen, F. M., Lieben, C. K., Jolles, J., Deutz, N. E. P., & Schmitt, J. A. J. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1933-4 · Cited by 17
The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression
Li, X., Li, J., Huang, Y., Gong, Q., Fu, Y., Xu, Y., Huang, J., You, H., Zhang, D., Zhang, D., et al. (2021) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2021.114045 · Cited by 16
Bilobalide modulates serotonin-controlled behaviors in the nematode Caenorhabditis elegans
Brown, M. K., & Luo, Y. (2009) · BMC Neuroscience · doi:10.1186/1471-2202-10-62 · Cited by 17
Presynaptic modulation of 5-HT release in the rat septal region
Rutz, S., Riegert, C., Rothmaier, A. K., & Jackisch, R. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.02.005 · Cited by 17
Facilitation of cholinergic transmission by combined treatment of ondansetron with flumazenil after cortical cholinergic deafferentation
Gil-Bea, F. J., Domínguez, J., Garcı́a-Alloza, M., Marcos, B., Lasheras, B., & Ramírez, M. J. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.03.014 · Cited by 17
Behavioral, Neurochemical and Neuroendocrine Effects of Abnormal Savda Munziq in the Chronic Stress Mice
Amat, N., Hoxur, P., Ming, D., Matsidik, A., Kijjoa, A., & Upur, H. (2012) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2012/426757 · Cited by 17
Neurotransmitters and neuromodulators involved in learning and memory
Bairy, L. K., & Kumar, S. G. (2019) · International Journal of Basic & Clinical Pharmacology · doi:10.18203/2319-2003.ijbcp20195296 · Cited by 16
Exploring role of natural compounds in molecular alterations associated with brain ageing: A perspective towards nutrition for ageing brain
Siddiqui, N., Sharma, A. K., Kesharwani, A., Anurag, & Parihar, V. K. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102282 · Cited by 16
Neonatal serotonin (5-HT) depletion does not affect spatial learning and memory in rats
Piechal, A., Blecharz‐Klin, K., Wyszogrodzka, E., Kołomańska, P., Rok-Bujko, P., Krząścik, P., Kostowski, W., Widy‐Tyszkiewicz, E., Filip, M., & Stefański, R. (2012) · Pharmacological Reports · doi:10.1016/s1734-1140(12)70764-8 · Cited by 16
Alterations of 5-HT1A receptor-induced G-protein functional activation and relationship to memory deficits in patients with pharmacoresistant temporal lobe epilepsy
Cuéllar‐Herrera, M., Velasco, A. L., Velasco, F., Trejo, D., Alonso‐Vanegas, M., Nuche‐Bricaire, A., Vázquez-Barrón, D., Guevara‐Guzmán, R., & Rocha, L. (2014) · Epilepsy Research · doi:10.1016/j.eplepsyres.2014.09.013 · Cited by 16
Brain serotonin 4 receptor binding is inversely associated with verbal memory recall
Stenbæk, D. S., Fisher, P. M., Ozenne, B., Andersen, E., Hjordt, L. V., McMahon, B., Hasselbalch, S. G., Frøkjær, V. G., & Knudsen, G. M. (2017) · Brain and Behavior · doi:10.1002/brb3.674 · Cited by 16
Psychogenetics and sport
Валерьевна, В. Е., Ahmetov, I. I., & Rees, T. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816193-7.00007-5 · Cited by 16
Serotonergic mechanisms of memory trace retrieval
Molodtsova, G. F. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.12.005 · Cited by 16
Differentiation of MDMA or 5-MeO-DIPT induced cognitive deficits in rat following adolescent exposure.
Compton, D. M., Selinger, M. C., Westman, E., & Otero, P. (2011) · Psychology & Neuroscience · doi:10.3922/j.psns.2011.1.018 · Cited by 16
The serotonin system in the hippocampus CA3 involves in effects of CSDS on social recognition in adult female mandarin voles (Microtus mandarinus)
Wang, L., He, Z., Zhu, Z., Yuan, W., Cai, W., Li, L., Zhang, J., Hou, W., Yang, Y., Zhang, X., et al. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.109704 · Cited by 16
The selective 5-HT1A receptor antagonist NAD-299 increases acetylcholine release but not extracellular glutamate levels in the frontal cortex and hippocampus of awake rat
Kehr, J., Hu, X.-J., Yoshitake, T., Wang, F.-H., Osborne, P. G., Stenfors, C., & Ögren, S. O. (2010) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2010.03.003 · Cited by 16
Unveiling serotonergic dysfunction of obsessive-compulsive disorder on prefrontal network dynamics: a computational perspective
Yin, L., Yu, Y., Han, F., & Wang, Q. (2024) · Cerebral Cortex · doi:10.1093/cercor/bhae258 · Cited by 16
Inhibition of gustatory plasticity due to acute nicotine exposure in the nematode Caenorhabditis elegans
Matsuura, T., Miura, H., & Nishino, A. (2013) · Neuroscience Research · doi:10.1016/j.neures.2013.09.001 · Cited by 15
Dose–response effects of chronic lithium regimens on spatial memory in the black molly fish
Creson, T. K., Woodruff, M. L., Ferslew, K. E., Rasch, E. M., & Monaco, P. J. (2003) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(03)00038-8 · Cited by 15
Neuroprotective Effect of Paroxetine on Memory Deficit Induced by Cerebral Ischemia after Transient Bilateral Occlusion of Common Carotid Arteries in Rat.
Naderi, Y., Parvardeh, S., Zanjani, T. M., & Sabetkasaei, M. (2018) · Europe PMC (PubMed Central) · Cited by 15
Effects of acute tryptophan depletion on cognition, memory and motor performance in Parkinson's disease
Scholtissen, B., Verhey, F. R. J., Adam, J. J., Prickaerts, J., & Leentjens, A. F. G. (2006) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2006.05.029 · Cited by 15
The effects of drug detection training on behavioral reactivity and blood neurotransmitter levels in drug detection dogs: A preliminary study
Riva, J., Marelli, S. P., Redaelli, V., Bondiolotti, G., Sforzini, E., Santoro, M. M., Carenzi, C., Verga, M., & Luzi, F. (2012) · Journal of Veterinary Behavior · doi:10.1016/j.jveb.2011.04.002 · Cited by 14
The Influence of Sertraline on Attention and Verbal Memory in Children and Adolescents with Anxiety Disorders
Günther, T., Holtkamp, K., JOLLES, J., Herpertz‐Dahlmann, B., & Konrad, K. (2005) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2005.15.608 · Cited by 14
Pharmacophore Comparison and Development of Recently Discovered Long Chain Arylpiperazine and Sulfonamide Based 5-HT7 Ligands
Rague, A. L., & Tidgewell, K. J. (2018) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/1389557517666170913111533 · Cited by 14
Systemic serotonin sulfate in opisthobranch mollusks
Stuart, J. N., Ebaugh, J. D., Copes, A. L., Hatcher, N. G., Gillette, R., & Sweedler, J. V. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02538.x · Cited by 14
Positron emission tomography imaging of the aging brain
MELTZER, C. C., Becker, J. T., Price, J. C., & Moses‐Kolko, E. L. (2003) · Neuroimaging Clinics of North America · doi:10.1016/s1052-5149(03)00108-4 · Cited by 14
Age-Related Alterations in the Behavior and Serotonin-Related Gene mRNA Levels in the Brain of Males and Females of Short-Lived Turquoise Killifish (Nothobranchius furzeri)
Evsiukova, V. S., Kulikova, E. A., & Kulikov, A. V. (2021) · Biomolecules · doi:10.3390/biom11101421 · Cited by 13
Differences in memory function between 5-HT1A receptor genotypes in patients with major depressive disorder
Wesnes, K. A., Hopkins, S. C., Brooker, H. J., & Koblan, K. S. (2016) · CNS Spectrums · doi:10.1017/s1092852915000802 · Cited by 13
Fluoxetine-Induced Memory Impairment in Four Family Members
Huang, S.-C., Tsai, S., & Chang, J. C. C. (2004) · The International Journal of Psychiatry in Medicine · doi:10.2190/dy6d-33bp-5wpb-1vdx · Cited by 13
Rehabilitating a brain with Alzheimer's: a proposal
Aranda-Abreu, G. E., Hernández‐Aguilar, M. E., Manzo, J., Herrera-Rivero, M., & García, L. I. (2011) · Clinical Interventions in Aging · doi:10.2147/cia.s14008 · Cited by 14
Interleukin-15 alters hippocampal synaptic transmission and impairs episodic memory formation in mice
Castro, M. A. D., Garofalo, S., Mormino, A., Carbonari, L., Pietro, E. D., Felice, E. D., Catalano, M., Maggi, L., & Limatola, C. (2023) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2023.11.015 · Cited by 14
Influence of acute tryptophan depletion on verbal declarative episodic memory in young adult females
Helmbold, K., Bubenzer, S., Dahmen, B., Eisert, A., Gaber, T. J., Habel, U., Konrad, K., Herpertz‐Dahlmann, B., & Zepf, F. D. (2013) · Amino Acids · doi:10.1007/s00726-013-1582-1 · Cited by 12
Antidepressive mechanisms of rhynchophylline in mice with chronic unpredictable stress-induced depression
Liu, E.-Y., Yang, C.-L., Tsai, J.-C., Cheng, H., & Peng, W. (2023) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2023.116302 · Cited by 12
Role of naloxone as an exogenous opioid receptor antagonist in spatial learning and memory of female rats during the estrous cycle
Farhadinasab, A., Shahidi, ‬., Najafi, A., & Komaki‬, A. (2008) · Brain Research · doi:10.1016/j.brainres.2008.12.043 · Cited by 12
Carbon Disulfide (CS 2 ) Interference in Glucose Metabolism from Unconventional Oil and Gas Extraction and Processing Emissions
Rich, A., Patel, J. T., & Al‐Angari, S. S. (2016) · Environmental Health Insights · doi:10.4137/ehi.s31906 · Cited by 12
Traditional Korean herbal formulae, Yuk-Mi-Ji-Hwang-Tang, ameliorates impairment of hippocampal memory ability by chronic restraint stress of mouse model
Eom, T.-M., Kwon, H. H., Shin, N., Kim, D. W., Fang, Z., Seol, I.-C., Kim, Y.-S., Kim, H.-G., & Yoo, H.-R. (2020) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2020.113102 · Cited by 12
Three Cases of Zolpidem Dependence Treated with Fluoxetine: The Serotonin Hypothesis
Liappas, I., Malitas, P. N., Dimopouloss, N. P., Gitsas, O. E., Liappas, A., Nikolaous, C. K., & Christodoulous, G. N. (2003) · The World Journal of Biological Psychiatry · doi:10.3109/15622970309167957 · Cited by 12
Histochemical study of acute and chronic intraperitoneal nicotine effects on several glycolytic and Krebs cycle dehydrogenase activities in the frontoparietal cortex and subcortical nuclei of the rat brain
Turégano, L., Martínez-Rodríguez, R., Álvarez, M., Gragera, R., Segura, A., de Miguel, E., & Tolédano, A. (2001) · Journal of Neuroscience Research · doi:10.1002/jnr.1116 · Cited by 12
Ultrafast capillary electrophoresis and bioanalytical applications
Stuart, J. N., & Sweedler, J. V. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0830869100 · Cited by 12
IUPHAR review: Moving beyond dopamine-based therapeutic strategies for schizophrenia
Moran, P. M., & Granger, K. T. (2025) · Pharmacological Research · doi:10.1016/j.phrs.2025.107727 · Cited by 13
Augmentation therapy with tandospirone citrate in vascular depression patients with mild cognitive impairment: A prospective randomized clinical trial
Chen, R., Lin, Q., Wu, J., Lin, Y., Lin, T., Wu, W., Chen, X., Wu, S., Zeng, G., Lin, X., et al. (2022) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2022.12.023 · Cited by 11
Acquisition session length modulates consolidation effects produced by 5-HT2C ligands in a mouse autoshaping-operant procedure
Walker, E. A., & Foley, J. J. (2010) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e328337bde7 · Cited by 11
Polymorphism C in the serotonin transporter gene (SLC6A4) in questionable dementia and Alzheimer's disease
Seripa, D., Franceschi, M., D’Onofrio, G., Panza, F., Cascavilla, L., Paris, F., Placentino, G., Matera, M. G., Solfrizzi, V., & Pilotto, A. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.04.076 · Cited by 11
Hippocampal glutamate-glutamine (Glx) in adults with Down syndrome: a preliminary study using in vivo proton magnetic resonance spectroscopy (1H MRS)
Tan, G. M., Beacher, F. D. C. C., Daly, E., Horder, J., Prasher, V., Hanney, M. L., Morris, R. G., Lovestone, S., Murphy, K. C., Simmons, A., et al. (2014) · Journal of Neurodevelopmental Disorders · doi:10.1186/1866-1955-6-42 · Cited by 13
Is there a role for uridine and pyrimidine nucleosides in the treatment of vascular dementia?
Fornai, F., Busceti, C. L., Ferrucci, M., Lazzeri, G., & Ruggieri, S. A. (2002) · PubMed · Cited by 11
Region-specific decrease in 5-HT1A and 5-HT1B binding sites after intra-hippocampal ibotenic acid injections in the rat
Amara, D. A., Ségu, L., & Buhot, M. C. (2001) · Neuroscience Letters · doi:10.1016/s0304-3940(01)02080-8 · Cited by 11
Self-citation
Baseline and 8-OH-DPAT-induced release of acetylcholine in the hippocampus of aged rats with different levels of cognitive dysfunction
Lazaris, A., Bertrand, F., Lazarus, C., Galani, R., Stemmelin, J., Poirier, R., Kelche, C. R., & Cassel, J. (2003) · Brain Research · doi:10.1016/s0006-8993(02)04272-5 · Cited by 11
Tangeretin offers neuroprotection against colchicine-induced memory impairment in Wistar rats by modulating the antioxidant milieu, inflammatory mediators and oxidative stress in the brain tissue
Ogunro, O. B., Karigidi, M. E., Gyebi, G. A., Turkistani, A. A., & Almehmadi, A. H. (2025) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-025-04769-2 · Cited by 10
The 5‐HTTLPR long allele predicts two‐year longitudinal increases in cortisol and declines in verbal memory in older adults
Hirst, R. B., Jordan, J. T., Rose, S. M. S., Schneider, L. D., Kawai, M., Gould, C. E., Anker, L. A., Chick, C. F., Beaudreau, S. A., Hallmayer, J. F., et al. (2020) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5319 · Cited by 10
Preclinical study on camellia sinensis extract-loaded nanophytosomes for enhancement of memory-boosting activity: optimization by central composite design
Mane, V. B., Killedar, S. G., More, H. N., & Tare, H. L. (2024) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-024-00639-9 · Cited by 10
Discovery of 7-arylsulfonyl-1,2,3,4, 4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridines: Identification of a potent and selective 5-HT6 receptor antagonist showing activity in rat social recognition test
Tripathy, R., McHugh, R. J., Bacon, E. R., Salvino, J. M., Morton, G. C., Aimone, L. D., Huang, Z., Mathiasen, J. R., DiCamillo, A., Huffman, M. J., et al. (2011) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2011.12.026 · Cited by 10
Impaired pre-attentive auditory processing in opioid dependence with and without benzodiazepine co-dependence revealed by combined magnetoencephalography and electroencephalography
Kivisaari, R., Lehtinen, R., Autti, T. H., Puuskari, V., Jokela, O., Ahveninen, J., Rapeli, P., & Kähkönen, S. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2007.06.001 · Cited by 10
Uremia-caused changes of ghrelin system in hippocampus may be associated with impaired cognitive function of hippocampus
Lv, Z., Gao, J., Wang, L., Chen, Z., Yuan, H., Ma, X., Lu, J., Lv, J., Wu, X., Zhang, L., et al. (2016) · International Urology and Nephrology · doi:10.1007/s11255-016-1228-9 · Cited by 10
Androgen deficit changes the response to antidepressant drugs in tail suspension test in mice
Shao, S., Cui, Y. G., Chen, Z.-B., Zhang, B., Huang, S.-M., & Liu, X. (2020) · The Aging Male · doi:10.1080/13685538.2020.1762074 · Cited by 10
Effect of 4-Fluoro-N-(4-sulfamoylbenzyl) Benzene Sulfonamide on cognitive deficits and hippocampal plasticity during nicotine withdrawal in rats
Rehman, N. U., Esmaeilpour, K., Joushi, S., Abbas, M., al‐Rashida, M., Rauf, K., & Masoumi‐Ardakani, Y. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110783 · Cited by 10
5-Hydroxytryptamine Receptors
Hoyer, D. (2007) · xPharm: The Comprehensive Pharmacology Reference · doi:10.1016/b978-008055232-3.60122-9 · Cited by 10
Increasing the number of 5-HT1A-receptors in cortex and hippocampus does not induce mnemonic deficits in mice
Bert, B., Voigt, J., Kusserow, H., Theuring, F., Rex, A., & Fink, H. (2008) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2008.10.014 · Cited by 10

Authors: Buhot, M.-C., Martin, S., & Segu, L.
Affiliations: Centre National de la Recherche Scientifique (FR)
Corresponding author: Buhot, Marie-Christine
Venue: Annals of Medicine
Publisher: Informa UK Limited
Published: 2000-01
Volume: 32
Issue: 3
Pages: 210-221
ISSN: 0785-3890 (ISSN-L)
1365-2060
DOI: 10.3109/07853890008998828
OpenAlex: W1973475326
Cited by: 419
References: 123
Citations by year: 2026: 4 · 2025: 8 · 2024: 13 · 2023: 12 · 2022: 9 · 2021: 19 · 2020: 15 · 2019: 14 · 2018: 8 · 2017: 11 · 2016: 13 · 2015: 8 · 2014: 19 · 2013: 18 · 2012: 15
FWCI: 6.29
Type: journal article
Language: en
Open access: closed
Locations: Annals of Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords: serotonin, serotonin receptors, memory impairment, learning, 5-HT2A/2C receptors, 5-HT4 receptor, 5-HT1A receptor, 5-HT3 receptor, 5-HT1B receptor, serotonergic system, nucleus basalis magnocellularis, cholinergic system, glutamatergic system, dopaminergic system, GABAergic system, inducible knockout mice
MeSH terms: Aging, Alzheimer Disease, Animals, Brain, Cognition, Humans, Limbic System, Memory Disorders, Receptors, Serotonin, Serotonin, Mice, Knockout, Mice

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Role of serotonin in memory impairment.

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks