The DOI matches its Crossref record; 74 of the 74 references it cites were found in a registry or an index.
Interaction of nanoparticles and cell-penetrating peptides with skin for transdermal drug delivery
Open accessAbstract
Topical or transdermal drug delivery is challenging because the skin acts as a natural and protective barrier. Therefore, several methods have been examined to increase the permeation of therapeutic molecules into and through the skin. One approach is to use the nanoparticulate delivery system. Starting with liposomes and other vesicular systems, several other types of nanosized drug carriers have been developed such as solid lipid nanoparticles, nanostructured lipid carriers, polymer-based nanoparticles and magnetic nanoparticles for dermatological applications. This review article discusses how different particulate systems can interact and penetrate into the skin barrier. In this review, the effectiveness of nanoparticles, as well as possible mode of actions of nanoparticles, is presented. In addition to nanoparticles, cell-penetrating peptide (CPP)-mediated drug delivery into the skin and the possible mechanism of CPP-derived delivery into the skin is discussed. Lastly, the effectiveness and possible mechanism of CPP-modified nanocarriers into the skin are addressed.
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1 retracted
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RetractedSolid lipid nanoparticles Production, characterization and applications
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The 500 Dalton rule for the skin penetration of chemical compounds and drugs
Bos, J. D., & Meinardi, M. M. H. M. (2000) · Experimental Dermatology · doi:10.1034/j.1600-0625.2000.009003165.x · Cited by 1,465
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Polyarginine enters cells more efficiently than other polycationic homopolymers
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Transdermal drug delivery: overcoming the skin’s barrier function
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Cited by
Skin cancer and new treatment perspectives: A review
Simões, M. C. F., Sousa, J. J. S., & Pais, A. A. C. C. (2015) · Cancer Letters · doi:10.1016/j.canlet.2014.11.001 · Cited by 414
Overcoming the skin permeation barrier: Challenges and opportunities
Vitorino, C., Sousa, J., & Pais, A. (2015) · Current Pharmaceutical Design · doi:10.2174/1381612821666150428124053 · Cited by 78
Metadata
- Authors
- Desai, P., Patlolla, R. R., & Singh, M.
- Venue
- Molecular Membrane Biology
- Publisher
- Informa UK Limited
- Published
- 2010-10
- Volume
- 27
- Issue
- 7
- Pages
- 247-259
- ISSN
- 0968-7688 (ISSN-L)
- 1464-5203
- OpenAlex
- W1983727696
- Cited by
- 411
- References
- 74
- FWCI
- 9.04
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Desai, P., Patlolla, R. R., & Singh, M. (2010). Interaction of nanoparticles and cell-penetrating peptides with skin for transdermal drug delivery. Molecular Membrane Biology. https://doi.org/10.3109/09687688.2010.522203
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
