A case of kleptomania and compulsive sexual behavior treated with naltrexone
Abstract
Objective of this paper was to examine a possible treatment option for two disorders currently lacking agreed upon pharmacotherapeutic interventions. We report a patient fulfilling DSM-IV criteria for kleptomania with comorbid compulsive sexual behavior who failed to respond to fluoxetine, behavioral therapy, and psychotherapy, and who was therefore treated with naltrexone to reduce urges to steal and sexual urges. Treatment with high-dose naltrexone (150 mg/day) led to remission of both the patient's urges to steal and sexual urges. Discontinuation and rechallenge with the medication provides further support that improvement was due to naltrexone. Naltrexone in high doses show promise for the treatment of both kleptomania and compulsive sexual behavior.
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The success of the opioid antagonist naltrexone in treating sex addiction, also used to treat drug addiction, is compatible with an addiction model for sexual behavior.
“The success of the opioid antagonist naltrexone in treating sex addiction, also used to treat drug addiction, (Grant and Kim, 2001;Kraus et al., 2015;Sultana and Din, 2022) is compatible with an addiction model for sexual behavior.”
From A motivation model of sex addiction – Relevance to the controversy over the concept (2022) · cites this paper as Grant and Kim, 2001
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- Authors
- Grant, J., & Kim, S. W.
- Affiliations
- University of Minnesota (US)
- ORCID
- Grant, Jon
- Venue
- Annals of Clinical Psychiatry
- Publisher
- SAGE Publications
- Published
- 2001-12-01
- Volume
- 13
- Issue
- 4
- Pages
- 229-231
- ISSN
- 1040-1237 (ISSN-L)
- OpenAlex
- W4240892151
- Cited by
- 55
- References
- 0
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2023: 1 · 2022: 5 · 2021: 2 · 2020: 4 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 3 · 2015: 4 · 2014: 4 · 2013: 2 · 2012: 2
- FWCI
- 0.89
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Clinical Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
- Social Sciences › Psychology › Clinical Psychology › Sexuality, Behavior, and Technology
- Keywords
- kleptomania, compulsive sexual behavior, naltrexone, pharmacotherapy, addiction treatment
- MeSH terms
- Compulsive Behavior, Humans, Disruptive, Impulse Control, and Conduct Disorders, Male, Middle Aged, Naltrexone, Narcotic Antagonists, Sexual Behavior, Treatment Outcome
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