The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Quenching the quorum sensing system: potential antibacterial drug targets
Abstract
Emergence of antibiotic and multi-drug resistant pathogenic bacteria has created the need for new drugs and drug targets. During pathogenesis bacteria release signals which regulate virulence and pathogenicity related genes. Such bacteria co-ordinate their virulent behaviour in a cell density dependent phenomenon termed as quorum sensing (QS). In contrast, microbes interfere with QS system by quenching the signals, termed quorum quenching (QQ). As a consequence of disrupted QS, pathogens become susceptible to antibiotics and drugs. In this article, the biodiversity of organisms with potential to quench QS signals and the use of QQ molecules as antibacterial drugs have been reviewed.
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Cites
Drugs for bad bugs: confronting the challenges of antibacterial discovery
Payne, D. J., Gwynn, M. N., Holmes, D. J., & Pompliano, D. L. (2007) · Nature Reviews Drug Discovery · doi:10.1038/nrd2201 · Cited by 2,512
Cellular Control of the Synthesis and Activity of the Bacterial Luminescent System
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Saiman, L., Marshall, B. C., Mayer-Hamblett, N., Burns, J. L., Quittner, A. L., Cibene, D. A., Coquillette, S., Fieberg, A. Y., Accurso, F. J., Campbell III, P. W., et al. (2003) · JAMA · doi:10.1001/jama.290.13.1749 · Cited by 958
Bacteria–host communication: the language of hormones
Sperandio, V., Torres, A. G., Jarvis, B., Nataro, J. P., & Kaper, J. B. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1537100100 · Cited by 902
A Pseudomonas aeruginosa quorum‐sensing molecule influences Candida albicans morphology
Hogan, D. A., Vik, Å., & Kolter, R. (2004) · Molecular Microbiology · doi:10.1111/j.1365-2958.2004.04349.x · Cited by 575
Potential application of gaseous nitric oxide as a topical antimicrobial agent
Ghaffari, A., Miller, C. C., McMullin, B., & Ghahary, A. (2006) · Nitric Oxide · doi:10.1016/j.niox.2005.08.003 · Cited by 236 · cited 1×
“Nitric oxide is a reactive free radical which kills cells within established biofilms (Barraud et al. 2006; Ghaffari et al. 2006; Hetrick et al. 2008; Hetrick et al. 2009).”
Background
Cited by
Combating Multidrug‐Resistant Bacteria: Current Strategies for the Discovery of Novel Antibacterials
O'Connell, K. M. G., Hodgkinson, J. T., Sore, H. F., Welch, M., Salmond, G. P. C., & Spring, D. R. (2013) · Angewandte Chemie International Edition · doi:10.1002/anie.201209979 · Cited by 435
Shrout, J. D., & Nerenberg, R. (2012) · Environmental Science & Technology · doi:10.1021/es203933h · Cited by 339
Sharma, C., Rokana, N., Chandra, M., Singh, B. P., Gulhane, R. D., Gill, J. P. S., Ray, P., Puniya, A. K., & Panwar, H. (2018) · Frontiers in Veterinary Science · doi:10.3389/fvets.2017.00237 · Cited by 308
Biofilms: Architecture, Resistance, Quorum Sensing and Control Mechanisms
Saxena, P., Joshi, Y., Rawat, K., & Bisht, R. (2019) · Indian Journal of Microbiology · doi:10.1007/s12088-018-0757-6 · Cited by 216
Genetic control of bacterial biofilms
Wolska, K. I., Grudniak, A. M., Rudnicka, Z., & Markowska, K. (2016) · Journal of Applied Genetics · doi:10.1007/s13353-015-0309-2 · Cited by 154
Metadata
- Authors
- Kalia, V. C., & Purohit, H. J.
- Venue
- Critical Reviews in Microbiology
- Publisher
- Informa UK Limited
- Published
- 2011-01-27
- Volume
- 37
- Issue
- 2
- Pages
- 121-140
- ISSN
- 1040-841X (ISSN-L)
- 1549-7828
- OpenAlex
- W2071144001
- Cited by
- 310
- References
- 6
- FWCI
- 7.52
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
