The DOI matches its Crossref record; 84 of the 84 references it cites were found in a registry or an index.
Silver as an antimicrobial: facts and gaps in knowledge
Abstract
Silver has been used for centuries. Today, silver and silver nanoparticles (AgNPs) are used in a wide range of healthcare, food industry, domiciliary applications, and are commonly found in hard surface materials and textiles. Such an extensive use raises questions about its safety, environmental toxicity and the risks associated with microbial resistance and cross-resistance. If the mechanisms of antimicrobial action of ionic silver (Ag+) have been studied, there is little understanding of AgNPs interactions with microorganisms. There have been excellent reviews on the bacterial resistance mechanisms to silver, but there is a paucity of information on resistance to AgNPs. Silver toxicity and accumulation in the environment has been studied and there is a better understanding of silver concentration and species in different environmental compartments. However, owing to the increased applications of silver and AgNPs, questions remain about the presence and consequences of AgNPs in the environment. This review provides an historical perspective of silver usage, an overview of applications, and combined information of microbial resistance and toxicity. Owing the evidence provided in this review, a call for a better understanding and control of silver usage, and for tighter regulations of silver and AgNPs usage is proposed.
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Cites
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Cited by
Silver nanoparticles: A new view on mechanistic aspects on antimicrobial activity
Durán, N., Durán, M., de Jesus, M. B., Seabra, A. B., Fávaro, W. J., & Nakazato, G. (2016) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2015.11.016 · Cited by 1,542
Rodrigues, A. S., Batista, J. G. S., Rodrigues, M. Á. V., Thipe, V. C., Minarini, L. A. R., Lopes, P. S., & Lugão, A. B. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1440065 · Cited by 346
Mohammed, H., Kumar, A., Bekyarova, E., Al-Hadeethi, Y., Zhang, X., Chen, M., Ansari, M. S., Cochis, A., & Rimondini, L. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.00465 · Cited by 312
Silver-coordination polymer network combining antibacterial action and shape memory capabilities
Wang, L., Wang, W., Di, S., Yang, X., Chen, H., Gong, T., & Zhou, S. (2014) · RSC Adv. · doi:10.1039/c4ra03829k · Cited by 27
Metadata
- Authors
- Maillard, J.-Y., & Hartemann, P.
- Venue
- Critical Reviews in Microbiology
- Publisher
- Informa UK Limited
- Published
- 2012-08-28
- Volume
- 39
- Issue
- 4
- Pages
- 373-383
- ISSN
- 1040-841X (ISSN-L)
- 1549-7828
- OpenAlex
- W1989137900
- Cited by
- 345
- References
- 84
- FWCI
- 6.95
- Type
- journal article
- Language
- en
- Open access
- closed
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- Maillard, J.-Y., & Hartemann, P. (2013). Silver as an antimicrobial: facts and gaps in knowledge. Critical Reviews in Microbiology. https://doi.org/10.3109/1040841x.2012.713323
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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