The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Proline-Dependent Structural and Biological Properties of Peptides and Proteins
Abstract
Proline residues confer unique structural constraints on peptide chains and markedly influence the susceptibility of proximal peptide bonds to protease activity. This review presents a critical analysis of peptidases involved in the cleavage of proline-containing peptide bonds, with particular attention to the role of proline peptidases in the regulation of the lifetime of biologically active peptides. Peptidases discussed include aminopeptidase P, prolidase, dipeptidyl peptidase IV, prolyl endopeptidase, and prolyl iminopeptidase. Attention is also given to HIV-1 protease, because this key enzyme processes an Xaa-Pro peptide bond. Analysis of the above enzymes reveals that they may function as key pacemakers in the control of the activity of many peptide hormones and that they are involved in a variety of immunological processes, including T-cell-mediated immune response. The novel occurrence of cis-trans isomerization about Xaa-Pro bonds and the biological function of peptidyl-prolyl cis-trans isomerases (immunophilins) are reviewed.
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Cites
Chou, P. Y., & Fasman, G. D. (1974) · Biochemistry · doi:10.1021/bi00699a001 · Cited by 2,172
Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands
Schreiber, S. L. (1991) · Science · doi:10.1126/science.1702904 · Cited by 1,494
Göttlinger, H. G., Sodroski, J. G., & Haseltine, W. A. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.15.5781 · Cited by 841
Hooper, N. M., Hryszko, J., & Turner, A. J. (1990) · Biochemical Journal · doi:10.1042/bj2670509 · Cited by 91
Kikuchi, M., Fukuyama, K., & Epstein, W. L. (1988) · Archives of Biochemistry and Biophysics · doi:10.1016/0003-9861(88)90268-8 · Cited by 30
Cited by
Kieffer, T. J., McIntosh, C. H., & Pederson, R. A. (1995) · Endocrinology · doi:10.1210/endo.136.8.7628397 · Cited by 1,124
Lambeir, A.-M., Durinx, C., Scharpé, S., & De Meester, I. (2003) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/713609354 · Cited by 955
CD26, let it cut or cut it down
De Meester, I., Korom, S., Van Damme, J., & Scharpé, S. (1999) · Immunology Today · doi:10.1016/s0167-5699(99)01486-3 · Cited by 451
Saier, M. H. (1994) · Microbiological Reviews · doi:10.1128/mmbr.58.1.71-93.1994 · Cited by 275
Abbott, C. A., McCaughan, G. W., Baker, E., & Sutherland, G. R. (1994) · Immunogenetics · doi:10.1007/bf01246674 · Cited by 177
Metadata
- Authors
- Yaron, A., Naider, F., & Scharpe, S.
- Venue
- Critical Reviews in Biochemistry and Molecular Biology
- Publisher
- Informa UK Limited
- Published
- 1993-01
- Volume
- 28
- Issue
- 1
- Pages
- 31-81
- ISSN
- 0045-6411 (ISSN-L)
- 1040-9238
- 1549-7798
- OpenAlex
- W2162061338
- Cited by
- 551
- References
- 5
- FWCI
- 2.11
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yaron, A., Naider, F., & Scharpe, S. (1993). Proline-Dependent Structural and Biological Properties of Peptides and Proteins. Critical Reviews in Biochemistry and Molecular Biology. https://doi.org/10.3109/10409239309082572
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