The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Role of oxidative damage in toxicity of particulates
Abstract
Particulates are small particles of solid or liquid suspended in liquid or air. In vitro studies show that particles generate reactive oxygen species, deplete endogenous antioxidants, alter mitochondrial function and produce oxidative damage to lipids and DNA. Surface area, reactivity and chemical composition play important roles in the oxidative potential of particulates. Studies in animal models indicate that particles from combustion processes (generated by combustion of wood or diesel oil), silicate, titanium dioxide and nanoparticles (C60 fullerenes and carbon nanotubes) produce elevated levels of lipid peroxidation products and oxidatively damaged DNA. Biomonitoring studies in humans have shown associations between exposure to air pollution and wood smoke particulates and oxidative damage to DNA, deoxynucleotides and lipids measured in leukocytes, plasma, urine and/or exhaled breath. The results indicate that oxidative stress and elevated levels of oxidatively altered biomolecules are important intermediate endpoints that may be useful markers in hazard characterization of particulates.
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Cites
Halliwell, B., & Whiteman, M. (2004) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0705776 · Cited by 2,238
Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage
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Pacurari, M., Yin, X. J., Zhao, J., Ding, M., Leonard, S. S., Schwegler-Berry, D., Ducatman, B. S., Sbarra, D., Hoover, M. D., Castranova, V., et al. (2008) · Environmental Health Perspectives · doi:10.1289/ehp.10924 · Cited by 372
Li, N., Kim, S., Wang, M., Froines, J., Sioutas, C., & Nel, A. (2002) · Inhalation Toxicology · doi:10.1080/089583701753678571 · Cited by 249
TOXICOKINETICS AND EFFECTS OF FIBROUS AND NONFIBROUS PARTICLES
Oberdörster, G. (2002) · Inhalation Toxicology · doi:10.1080/089583701753338622 · Cited by 221
Shvedova, A. A., Kisin, E. R., Murray, A. R., Gorelik, O., Arepalli, S., Castranova, V., Young, S.-H., Gao, F., Tyurina, Y. Y., Oury, T. D., et al. (2007) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2007.03.018 · Cited by 163
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Cited by
Brook, R. D., Rajagopalan, S., Pope, C. A., Brook, J. R., Bhatnagar, A., Diez-Roux, A. V., Holguin, F., Hong, Y., Luepker, R. V., Mittleman, M. A., et al. (2010) · Circulation · doi:10.1161/cir.0b013e3181dbece1 · Cited by 6,548
Sharifi, S., Behzadi, S., Laurent, S., Laird Forrest, M., Stroeve, P., & Mahmoudi, M. (2012) · Chem. Soc. Rev. · doi:10.1039/c1cs15188f · Cited by 1,460
Review on nano zerovalent iron (nZVI): From synthesis to environmental applications
Stefaniuk, M., Oleszczuk, P., & Ok, Y. S. (2016) · Chemical Engineering Journal · doi:10.1016/j.cej.2015.11.046 · Cited by 935
Valavanidis, A., Vlachogianni, T., Fiotakis, K., & Loridas, S. (2013) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph10093886 · Cited by 910
Cytotoxicity and oxidative stress induced by different metallic nanoparticles on human kidney cells
Pujalté, I., Passagne, I., Brouillaud, B., Tréguer, M., Durand, E., Ohayon-Courtès, C., & L'Azou, B. (2011) · Particle and Fibre Toxicology · doi:10.1186/1743-8977-8-10 · Cited by 398
Metadata
- Authors
- Møller, P., Jacobsen, N. R., Folkmann, J. K., Danielsen, P. H., Mikkelsen, L., Hemmingsen, J. G., Vesterdal, L. K., Forchhammer, L., Wallin, H., & Loft, S.
- Venue
- Free Radical Research
- Publisher
- Informa UK Limited
- Published
- 2009-11-03
- Volume
- 44
- Issue
- 1
- Pages
- 1-46
- ISSN
- 1029-2470 (ISSN-L)
- 1071-5762
- OpenAlex
- W2114477244
- Cited by
- 453
- References
- 7
- FWCI
- 17.57
- Type
- journal article
- Language
- en
- Open access
- closed
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- Møller, P., Jacobsen, N. R., Folkmann, J. K., Danielsen, P. H., Mikkelsen, L., Hemmingsen, J. G., Vesterdal, L. K., Forchhammer, L., Wallin, H., & Loft, S. (2010). Role of oxidative damage in toxicity of particulates. Free Radical Research. https://doi.org/10.3109/10715760903300691
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.