The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Hazardous components and health effects of atmospheric aerosol particles: reactive oxygen species, soot, polycyclic aromatic compounds and allergenic proteins
Abstract
This review outlines recent advances in the investigation of the chemical properties, molecular interactions and health effects of hazardous compounds in atmospheric aerosols, in particular reactive oxygen species (ROS), soot, polycyclic aromatic compounds (PACs) and allergenic proteins. Epidemiological studies show correlations between air particulate matter and adverse health effects of air pollution including allergy, asthma, cardiovascular and respiratory diseases, but the causative relations and mechanisms of interaction on the molecular level are still unclear. ROS generated by photochemical and heterogeneous reactions in the atmosphere seem to play a key role in aerosol health effects and provide a direct link between atmospheric and physiological multiphase processes. Soot and PACs can trigger formation of ROS in vivo, leading to inflammation and cellular damage. PACs as well as allergenic proteins are efficiently oxygenated and nitrated upon exposure to ozone and nitrogen dioxide, which leads to an enhancement of their toxicity and allergenicity.
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Cites
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Pöschl, U., & Shiraiwa, M. (2015) · Chemical Reviews · doi:10.1021/cr500487s · Cited by 657
Self-citationThe Molecular Identification of Organic Compounds in the Atmosphere: State of the Art and Challenges
Nozière, B., Kalberer, M., Claeys, M., Allan, J., D’Anna, B., Decesari, S., Finessi, E., Glasius, M., Grgić, I., Hamilton, J. F., et al. (2015) · Chemical Reviews · doi:10.1021/cr5003485 · Cited by 656
Healy, D. A., Huffman, J. A., O'Connor, D. J., Pöhlker, C., Pöschl, U., & Sodeau, J. R. (2014) · Atmospheric Chemistry and Physics · doi:10.5194/acp-14-8055-2014 · Cited by 101
Self-citationPhenolic Melatonin-Related Compounds: Their Role as Chemical Protectors against Oxidative Stress
Galano, A., Castañeda-Arriaga, R., Pérez-González, A., Tan, D.-X., & Reiter, R. (2016) · Molecules · doi:10.3390/molecules21111442 · Cited by 60
Pereira, S., Fernández-González, M., Guedes, A., Abreu, I., & Ribeiro, H. (2021) · Forests · doi:10.3390/f12010088 · Cited by 18
Metadata
- Authors
- Shiraiwa, M., Selzle, K., & Pöschl, U.
- Venue
- Free Radical Research
- Publisher
- Informa UK Limited
- Published
- 2012-04-23
- Volume
- 46
- Issue
- 8
- Pages
- 927-939
- ISSN
- 1029-2470 (ISSN-L)
- 1071-5762
- OpenAlex
- W2020473888
- Cited by
- 195
- References
- 12
- FWCI
- 7.24
- Type
- journal article
- Language
- en
- Open access
- closed
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- Shiraiwa, M., Selzle, K., & Pöschl, U. (2012). Hazardous components and health effects of atmospheric aerosol particles: reactive oxygen species, soot, polycyclic aromatic compounds and allergenic proteins. Free Radical Research. https://doi.org/10.3109/10715762.2012.663084
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