RETRACTED ARTICLE: Bright light treatment as mono-therapy of non-seasonal depression for 28 adolescents
Abstract
BACKGROUND: Bright light therapy, an effective therapeutic option for depressive adults, could provide safe, economic, and effective rapid recovery also in adolescents. METHODS: Twenty-eight volunteers, between 14 and 17 years old and suffering from mild depressive disorder according to DSM-IV criteria, completed the study. This was a randomized cross-over trial, i.e. that 14 patients received first placebo (50 lux) for 1 h a day for 1 week and then bright light therapy (2,500 Lux) for 1 week. Fourteen patients received first bright light therapy and then placebo. For assessment of depressive symptoms, Beck's depression inventory scales were administered 1 week before and 1 day before placebo treatment, on the day between placebo and verum treatment, on the day after verum treatment and 1 week after verum treatment. Saliva melatonin and cortisol samples were collected at 08:00 and 20:00 h, 1 week before and 1 day before placebo treatment, on the day between placebo and verum treatment, on the day after verum treatment and 1 week after verum treatment and assayed for melatonin and cortisol to observe any change in circadian timing. RESULTS: BDI scores improved significantly. The assays of saliva showed significant differences between treatment and placebo. No significant adverse reactions were observed. CONCLUSION: Antidepressant response to bright light treatment in this age group was statistically superior to placebo.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
One randomized cross-over trial of 28 adolescents with depression found bright light therapy (2,500 lux vs. placebo, 50 lux) induced an antidepressant response and a phase advance of cortisol and melatonin rhythms, with no adverse treatment effects.
“One randomized cross-over trial of 28 adolescents with depression found BLT (2,500 lux vs. placebo, 50 lux), induced an antidepressant response and a phase advance of cortisol and melatonin rhythms, with no adverse treatment effects (150).”
From Impact of Sleep and Circadian Rhythms on Addiction Vulnerability in Adolescents (2018) · cites this paper as [150]
Cites
Light therapy for Seasonal Affective Disorder A review of efficacy
TERMAN, M. (1989) · Neuropsychopharmacology · doi:10.1016/0893-133x(89)90002-x · Cited by 539 · see citing works
Khan, A., Warner, H. A., & Brown, W. A. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.4.311 · Cited by 475 · see citing works
Circadian Time of Morning Light Administration and Therapeutic Response in Winter Depression
Terman, J. S., Terman, M., Lo, E.-S., & Cooper, T. B. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.1.69 · Cited by 366 · see citing works
A Circadian Signal of Change of Season in Patients With Seasonal Affective Disorder
Wehr, T. A., Duncan, W. C., Sher, L., Aeschbach, D., Schwartz, P. J., Turner, E. H., Postolache, T. T., & Rosenthal, N. E. (2001) · Archives of General Psychiatry · doi:10.1001/archpsyc.58.12.1108 · Cited by 288 · see citing works
Lewy, A. J., Sack, R. L., Singer, C. M., Whate, D. M., & Hoban, T. M. (1988) · Journal of Biological Rhythms · doi:10.1177/074873048800300203 · Cited by 190 · see citing works
Morning vs Evening Light Treatment for Winter Depression
Sack, R. L. (1990) · Archives of General Psychiatry · doi:10.1001/archpsyc.1990.01810160043008 · Cited by 182 · see citing works
Bright light therapy stabilizes the antidepressant effect of partial sleep deprivation
Neumeister, A., Gößler, R., Lucht, M. J., Kapitany, T., Bamas, C., & Kasper, S. F. (1996) · Biological Psychiatry · doi:10.1016/0006-3223(95)00086-0 · Cited by 158 · see citing works
What the placebo literature can tell us about light therapy for SAD.
Eastman, C. I. (1990) · PubMed · Cited by 95 · see citing works
Depression and endogenous melatonin in postmenopausal women
Tuunainen, A. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(01)00303-2 · Cited by 77 · see citing works
Morning or evening bright light treatment of winter depression? The significance of hypersomnia
Avery, D., Khan, A., Dager, S. R., Cohen, S., Cox, G. B., & Dünner, D. L. (1991) · Biological Psychiatry · doi:10.1016/0006-3223(91)90040-s · Cited by 69 · see citing works
Bright light treatment of depression for older adults [ISRCTN55452501]
Loving, R. T., Kripke, D. F., Elliott, J. A., Knickerbocker, N. C., & Grandner, M. A. (2005) · BMC Psychiatry · doi:10.1186/1471-244x-5-41 · Cited by 61 · see citing works
Sekula, L. K., Lucke, J. F., Heist, E. K., Czambel, R. K., & Rubín, R. T. (1997) · Psychiatry Research · doi:10.1016/s0165-1781(96)02937-x · Cited by 59 · see citing works
Timing of phototherapy and occurrence of mania
Kripke, D. F. (1991) · Biological Psychiatry · doi:10.1016/0006-3223(91)90258-n · Cited by 33 · see citing works
Ruchlewska, A., Mulder, C., Smulders, R., Roosenschoon, B.-J., Koopmans, G. T., & Wierdsma, A. I. (2009) · BMC Psychiatry · doi:10.1186/1471-244x-9-41 · Cited by 24 · see citing works
Problems and Prospects for use of Bright Light as a Therapeutic Intervention
Terman, M. (1993) · Elsevier eBooks · doi:10.1016/b978-0-08-042279-4.50035-2 · Cited by 22 · see citing works
Light therapy for non-seasonal depression (Review)
Tuunainen, A., Df, K., & Endo, T. (2009) · Cited by 1 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Impact of Sleep and Circadian Rhythms on Addiction Vulnerability in Adolescents
Logan, R. W., Hasler, B. P., Forbes, E. E., Franzen, P. L., Torregrossa, M. M., Huang, Y. H., Buysse, D. J., Clark, D. B., & McClung, C. A. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.11.035 · Cited by 194 · see citing works
Zhou, T.-H., Dang, W.-M., Ma, Y.-T., Hu, C.-Q., Wang, N., Zhang, G.-Y., Wang, G., Shi, C., Zhang, H., Guo, B., et al. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.09.038 · Cited by 53 · see citing works
The antidepressant effect of light therapy from retinal projections.
Li, X., & Li, X. (2018) · Neuroscience Bulletin · doi:10.1007/s12264-018-0210-1 · Cited by 47 · see citing works
Canbeyli, R. (2022) · European Journal of Neuroscience · doi:10.1111/ejn.15507 · Cited by 48 · see citing works
A sham-controlled randomized trial of adjunctive light therapy for non-seasonal depression
Chojnacka, M., Antosik-Wójcińska, A. Z., Dominiak, M., Bzinkowska, D., Borzym, A., Sokół-Szawłowska, M., Bodzak-Opolska, G., Antoniak, D., & Święcicki, Ł. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2016.05.062 · Cited by 32 · see citing works
- Authors
- Niederhofer, H., & von Klitzing, K.
- Affiliations
- Sächsisches Krankenhaus Rodewisch (DE)
- Child and Adolescent Psychiatry, University of Leipzig, Leipzig, Germany
- Corresponding author
- Niederhofer, Helmut
- Venue
- International Journal of Psychiatry in Clinical Practice
- Publisher
- Informa UK Limited
- Published
- 2012-07-02
- Volume
- 16
- Issue
- 3
- Pages
- 233-237
- ISSN
- 1365-1501 (ISSN-L)
- 1471-1788
- OpenAlex
- W2147696422
- Cited by
- 37
- References
- 16
- Citations by year
- 2024: 1 · 2023: 2 · 2022: 1 · 2021: 1 · 2020: 5 · 2019: 3 · 2018: 2 · 2017: 8 · 2016: 2 · 2015: 4 · 2014: 3 · 2013: 4
- FWCI
- 2.59
- Type
- journal article
- Language
- en
- Status
- Retracted
- Update notices
- retraction (2021-06-15)
- Open access
- closed
- Locations
- International Journal of Psychiatry in Clinical Practice (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- bright light therapy, non-seasonal depression, adolescent depression, placebo-controlled intervention, circadian rhythm, salivary melatonin, salivary cortisol, Beck Depression Inventory
- MeSH terms
- Adolescent, Adult, Analysis of Variance, Circadian Rhythm, Depressive Disorder, Humans, Hydrocortisone, Melatonin, Phototherapy, Placebos, Psychiatric Status Rating Scales, Saliva, Treatment Outcome, Cross-Over Studies
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
