Cited by 185Menopause: Health Impacts and TreatmentsEstrogen and related hormone effectsSexual function and dysfunction studies

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Menopausal hot flushes and night sweats: where are we now?

Archer, D. F., Sturdee, D. W., Baber, R., de Villiers, T. J., Pines, A., Freedman, R. R., Gompel, A., Hickey, M., Hunter, M. S., Lobo, R. A., Lumsden, M. A., MacLennan, A. H., Maki, P., Palacios, S., Shah, D., Villaseca, P., Warren, M.·2011·Climacteric

DOI 10.3109/13697137.2011.608596

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Abstract

OBJECTIVE: An overview of the current knowledge on the etiology and treatment of vasomotor symptoms in postmenopausal women. MATERIALS AND METHODS: Acknowledged experts in the field contributed a brief assessment of their areas of interest which were combined and edited into the final manuscript. RESULTS: Women around the world experience vasomotor symptoms as they enter and complete the menopause transition. Vasomotor symptoms, specifically hot flushes, are caused by a narrowing of the thermoneutral zone in the brain. This effect, although related to estrogen withdrawal, is most likely related to changes in central nervous system neurotransmitters. Peripheral vascular reactivity is also altered in symptomatic women. Estrogen replacement therapy is the most effective treatment for hot flushes. Of the other interventions investigated, selective serotonin and selective norepinephrine reuptake inhibitors and gabapentin show efficacy greater than placebo. Objective monitoring of hot flushes indicates a robust improvement with hormone replacement therapy but little to no change with placebo. These data suggest that the subjective assessment of responses to therapy for vasomotor symptom results in inaccurate data. Hot flushes have recently been associated with increased cardiovascular risks and a lower incidence of breast cancer, but these data require confirmation. CONCLUSIONS: Vasomotor symptoms are experienced by women of all ethnic groups. They are caused by changes in the central nervous system associated with estrogen withdrawal and are best treated with estrogen replacement therapy. Objective monitoring of hot flushes indicates that placebo has little to no effect on their improvement. Subjective assessments of hot flushes in clinical trials may be inaccurate based on objective measurement of the frequency of hot flushes. Based on preliminary reports, women experiencing hot flushes have an increased risk of cardiovascular disease and a reduced incidence of breast cancer.

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Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial
Writing Group for the Women's Health Initiative Investigators (2002) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.288.3.321 · Cited by 15,889
Cochrane Database of Systematic Reviews
(2008) · Springer eBooks · doi:10.1007/978-1-4020-5614-7_436 · Cited by 4,552
Effects of Conjugated Equine Estrogen in Postmenopausal Women With Hysterectomy: The Women's Health Initiative Randomized Controlled Trial
(2004) · JAMA · doi:10.1001/jama.291.14.1701 · Cited by 4,534
Skin blood flow in adult human thermoregulation: How it works, when it does not, and why
Charkoudian, N. (2003) · Mayo Clinic Proceedings · doi:10.4065/78.5.603 · Cited by 1,041
Factors Associated with Age at Natural Menopause in a Multiethnic Sample of Midlife Women
Gold, E. B. (2001) · American Journal of Epidemiology · doi:10.1093/aje/153.9.865 · Cited by 862
Relation of demographic and lifestyle factors to symptoms in a multi-racial/ethnic population of women 40-55 years of age
Gold, E. B. (2000) · American Journal of Epidemiology · doi:10.1093/aje/152.5.463 · Cited by 861
Thermoregulation: some concepts have changed. Functional architecture of the thermoregulatory system
Romanovsky, A. A. (2007) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00668.2006 · Cited by 786
Postmenopausal Hormone Therapy: An Endocrine Society Scientific Statement
Santen, R. J., Allred, D. C., Ardoin, S. P., Archer, D. F., Boyd, N. F., Braunstein, G. D., Burger, H., Colditz, G. A., Davis, S. R., Gambacciani, M., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2509 · Cited by 687
Role of the preoptic-anterior hypothalamus in thermoregulation and fever
Boulant, J. A. (2000) · Clinical Infectious Diseases · doi:10.1086/317521 · Cited by 562
Oral oestrogen and combined oestrogen/progestogen therapy versus placebo for hot flushes
MacLennan, A. H., Broadbent, J. L., Lester, S., & Moore, V. (2004) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002978.pub2 · Cited by 543

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Freedman R, 1992, Themoregulation: The Pathophysiological Basis of Clinical Disorders, 6
Freedman RR, 1990, Obstet Gynecol, 76, 573
Sassarini J, 2011, Climacteric, 14, 87
Quan N, 1991, Am J Physiol, 261, R378
Quan N, 1992, Am J Physiol, 262, R407
Hunter M, 2011, Menopause
Erlik Y, 1982, Obstet Gynecol, 59, 403
Norman RJ, 2000, Cochrane Database of Systematic Reviews (Online), CD001018
Prior JC, 2010, Presented at ENDO
10.1200/JCO.2008.19.6253 · DOI
Rada G, Cochrane Database of Systematic Reviews
Ray D, 1993, Br J Hosp Med, 50, 594

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Authors: Archer, D. F., Sturdee, D. W., Baber, R., de Villiers, T. J., Pines, A., Freedman, R. R., Gompel, A., Hickey, M., Hunter, M. S., Lobo, R. A., Lumsden, M. A., MacLennan, A. H., Maki, P., Palacios, S., Shah, D., Villaseca, P., & Warren, M.
Affiliations: Eastern Virginia Medical School (US)
Solihull Hospital (GB)
The University of Sydney (AU)
Tel Aviv Sourasky Medical Center (IL)
Wayne State University (US)
Assistance Publique – Hôpitaux de Paris (FR)
Royal Women's Hospital (AU)
King's College London (GB)
University of Glasgow (GB)
The University of Adelaide (AU)
University of Illinois Chicago (US)
Instituto Palacios (ES)
Pontificia Universidad Católica de Chile (CL)
Columbia University (US)
ORCID: Archer, D. F.
Baber, R.
Gompel, A.
Hickey, M.
Hunter, M. S.
Lumsden, M. A.
MacLennan, A. H.
Maki, P.
Palacios, S.
Shah, D.
Villaseca, P.
Venue: Climacteric
Publisher: Informa UK Limited
Published: 2011-08-18
Volume: 14
Issue: 5
Pages: 515-528
ISSN: 1369-7137 (ISSN-L)
1473-0804
DOI: 10.3109/13697137.2011.608596
OpenAlex: W2025638598
Cited by: 185
References: 131
Citations by year: 2026: 6 · 2025: 11 · 2024: 8 · 2023: 11 · 2022: 12 · 2021: 9 · 2020: 11 · 2019: 16 · 2018: 16 · 2017: 12 · 2016: 18 · 2015: 13 · 2014: 15 · 2013: 18 · 2012: 8
FWCI: 1.82
Type: journal article
Language: en
Open access: closed
Locations: Climacteric (publishedVersion)
PubMed (publishedVersion)
Adelaide Research & Scholarship (AR&S) (University of Adelaide) (submittedVersion)
ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (submittedVersion)
Research Portal (King's College London) (submittedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Menopause: Health Impacts and Treatments
Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Estrogen and related hormone effects
Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
Keywords: hot flashes, night sweats, vasomotor symptoms, menopause, perimenopause, estrogen withdrawal, thermoneutral zone, peripheral vascular reactivity, hormone replacement therapy, selective serotonin reuptake inhibitors, selective norepinephrine reuptake inhibitors, gabapentin, cardiovascular risk, breast cancer risk
MeSH terms: Adult, Body Temperature Regulation, Brain, Breast Neoplasms, Cardiovascular Diseases, Estrogens, Female, Humans, Menopause, Middle Aged, Risk Factors, Sweating, Vasomotor System, Estrogen Replacement Therapy, Randomized Controlled Trials as Topic, Neurotransmitter Agents, Hot Flashes

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