The DOI matches its Crossref record; 86 of the 88 references it cites were found in a registry or an index.
From pre- to postweaning: Transformation of the young calf's gastrointestinal tract
Open accessAbstract
The ruminant gastrointestinal tract (GIT) faces the challenge of protecting the host from luminal contents and pathogens, while supporting the absorption and metabolism of nutrients for growth and maintenance. The GIT of the calf in early life undergoes some of the most rapid microbial and structural changes documented in nature, and these adaptations in GIT function make the young calf susceptible to GIT diseases and disorders. Despite these challenges, the calf's GIT has a certain degree of plasticity and can sense nutrient supply and respond to bioactive ingredients. Calf GIT research has historically focused on the transition during weaning and characterizing ruminal papillae development using microscopy and digesta metabolite responses. Through the use of new molecular-based approaches, we have recently shown that delaying the age of weaning and providing a step-down weaning protocol is associated with a more gradual shift in ruminal microbiota to a postweaned state. In addition to ruminal adaptations during weaning, nutrient flow to the lower gut changes dramatically during weaning, coinciding with a wide array of structural and microbiological changes. Structural and gene expression changes suggest that the lower gut of the dairy calf undergoes alterations that may reduce barrier function when solid feeds are consumed. More recently, in vivo data revealed that the weaning transition increases total gut permeability of the calf. Interestingly, the lower gut may be able to communicate with the forestomach, meaning that a nutrient can be sensed in the lower gut and cause subsequent adaptations in the forestomach. An improved understanding of how diet, microbiota, and functional ingredients interact to affect growth and barrier function of the intestinal tract would greatly benefit the dairy calf industry. A mechanistic understanding of such adaptations would also aid in the formulation of specific management regimens and provision of functional ingredients required to characterize and enhance gut function in young calves.
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“Additionally, young calves rely on milk for the majority of their nutrition, as their gastrointestinal tract is not fully developed for digesting solids (8).”
From Effect of source and journey on physiological variables in calves transported by road and ferry between Ireland and the Netherlands (2023) · cites this paper as [8]
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Citations
Cites
Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences
Langille, M. G. I., Zaneveld, J., Caporaso, J. G., McDonald, D., Knights, D., Reyes, J. A., Clemente, J. C., Burkepile, D. E., Vega Thurber, R. L., Knight, R., et al. (2013) · Nature Biotechnology · doi:10.1038/nbt.2676 · Cited by 9,116
Hungate, R. E. (2013) · Elsevier eBooks · doi:10.1016/c2013-0-12555-x · Cited by 3,060
Benson, A. K., Kelly, S. A., Legge, R., Ma, F., Low, S. J., Kim, J., Zhang, M., Oh, P. L., Nehrenberg, D., Hua, K., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1007028107 · Cited by 1,314
Exploring the bovine rumen bacterial community from birth to adulthood
Jami, E., Israel, A., Kotser, A., & Mizrahi, I. (2013) · The ISME Journal · doi:10.1038/ismej.2013.2 · Cited by 963
Allen, M. S. (1997) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(97)76074-0 · Cited by 889
Perspectives on Immunoglobulins in Colostrum and Milk
Hurley, W. L., & Theil, P. K. (2011) · Nutrients · doi:10.3390/nu3040442 · Cited by 691
Jiménez, E., Fernández, L., Marín, M. L., Martı́n, R., Odriozola, J. M., Nueno‐Palop, C., Narbad, A., Olivares, M. M., Xaus, J., & Rodríguez, J. M. (2005) · Current Microbiology · doi:10.1007/s00284-005-0020-3 · Cited by 681
Rumen Development, Intestinal Growth and Hepatic Metabolism In The Pre- and Postweaning Ruminant
Baldwin, R. L., McLeod, K. R., Klotz, J. L., & Heitmann, R. N. (2004) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(04)70061-2 · Cited by 654
Furness, J. B., Rivera, L. R., Cho, H., Bravo, D. M., & Callaghan, B. P. (2013) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/nrgastro.2013.180 · Cited by 584
Windeyer, M. C., Leslie, K. E., Godden, S. M., Hodgins, D. C., Lissemore, K. D., & LeBlanc, S. J. (2014) · Preventive Veterinary Medicine · doi:10.1016/j.prevetmed.2013.10.019 · Cited by 541
Research works printed but not linked: 3
- Forano, 2010, Structuration de l'écosystème ruminal chez le nouveau-né: Influence de facteurs écologiques, Bull. GTV, 52, 13
- Miyashige, 1980, Development of intestinal disaccharase activities in nursing calves, Jpn. J. Zootech. Sci., 51, 58
- Steele, 2015, Gradual weaning affects pre and post-weaning feed intake, growth and gastrointestinal development in Holstein calves fed an elevated plane of nutrition during the pre-weaning period, J. Anim. Sci., 98, 242
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Sorted by citations
Influence of the microbiota-gut-brain axis on behavior and welfare in farm animals: A review
Kraïmi, N., Dawkins, M. S., Gebhardt‐Henrich, S. G., Velge, P., Rychlı́k, I., Volf, J., Créach, P., Smith, A. L., Colles, F. M., & Leterrier, C. (2019) · Physiology & Behavior · doi:10.1016/j.physbeh.2019.112658 · Cited by 161
“early life have been described in several farm animals (chick: [87]; calf: [88,89]; piglet: [90]; foal: [91]).”
Klein-Jöbstl, D., Quijada, N. M., Dzieciol, M., Feldbacher, B., Wagner, M., Drillich, M., Schmitz‐Esser, S., & Mann, E. (2019) · PLoS ONE · doi:10.1371/journal.pone.0220554 · Cited by 126
Li, B., Zhang, K., Li, C., Wang, X., Chen, Y., & Yang, Y. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.02125 · Cited by 113
“Concomitant with the solid-feed intake and increase of microbial activity, the rumen then becomes functional and improves its absorptive and metabolic capacity by increasing its surface area and volume (Rey et al., 2012; Steele et al., 2016;Meale et al., 2017).”
BackgroundLong-term consistency of personality traits of cattle
Neave, H. W., Costa, J. H. C., Weary, D. M., & von Keyserlingk, M. A. G. (2020) · Royal Society Open Science · doi:10.1098/rsos.191849 · Cited by 84
Li, C., Wang, W., Liu, T., Zhang, Q., Wang, G., Li, F., Li, F., Yue, X., & Li, T. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01431 · Cited by 73
“Meale et al. (2017) also reported that host PRRs were stimulated post-weaning.”
Background
Metadata
- Authors
- Meale, S. J., Chaucheyras-Durand, F., Berends, H., Guan, L. L., & Steele, M. A.
- Affiliations
- Unité Mixte de Recherche sur les Herbivores (FR)
- Trouw Nutrition (Brazil) (BR)
- University of Alberta (CA)
- Corresponding author
- Steele, Michael A.
- Venue
- Journal of Dairy Science
- Publisher
- American Dairy Science Association
- Published
- 2017-07
- Volume
- 100
- Issue
- 7
- Pages
- 5984-5995
- ISSN
- 0022-0302 (ISSN-L)
- OpenAlex
- W2616070946
- Cited by
- 163
- References
- 88
- Citations by year
- 2026: 17 · 2025: 17 · 2024: 15 · 2023: 31 · 2022: 23 · 2021: 19 · 2020: 14 · 2019: 12 · 2018: 13 · 2017: 2
- FWCI
- 19.50
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Dairy Science (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Funders
- University of Alberta
- Topics
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Ruminant Nutrition and Digestive Physiology
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Nutrition and Physiology
- Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal health and immunology
- Keywords
- gastrointestinal tract development, weaning transition, ruminal papillae, rumen microbiota, intestinal permeability, forestomach, functional feed ingredients, gut microbiota, gene expression
- MeSH terms
- Animals, Animal Feed, Animals, Newborn, Cattle, Diet, Rumen, Weaning, Gastrointestinal Tract
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