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Cited by 143Milk Quality and Mastitis in Dairy CowsRuminant Nutrition and Digestive PhysiologyAnimal health and immunology

The DOI matches its Crossref record; 23 of the 24 references it cites were found in a registry or an index.

Suppression of Milk Production During Endotoxin-Induced Mastitis

Open access
Shuster, D.E., Harmon, R.J., Jackson, J.A., Hemken, R.W.·1991·Journal of Dairy Science
DOI 10.3168/jds.s0022-0302(91)78568-8
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Abstract

Healthy, midlactation cows were given intramammary infusions of 10 micrograms of endotoxin in two homolateral quarters. Productive, inflammatory, and systemic responses were studied to investigate the pathophysiological effects of mastitis on lactational performance. Endotoxin suppressed milk yield in all quarters of treated cows. A more severe and prolonged suppression occurred in infused quarters compared with uninfused quarters. The fat percentage of milk from all quarters was increased with a greater increase occurring in infused quarters. The protein composition of milk was elevated, and the lactose concentration was depressed in infused quarters. Mammary inflammation--as measured by milk SCC, NAGase, serum albumin, and lactoferrin--was limited to infused quarters. Changes in milk NAGase closely paralleled changes in milk SCC. Daily feed intake was unaffected, and serum glucose levels did not decline following infusion. The lactose concentration of urine increased rapidly after infusion. Reduction in milk yield in all quarters, but varying changes in milk composition in infused versus uninfused quarters suggest that mastitic hypogalactia is mediated by multiple pathophysiological events and is not solely due to inflammatory damage to the mammary epithelium. Part of the reduced lactational performance may result from escape of milk components from the udder into the circulation.

Overview

Integrity signals

Registry

Crossref · 10.3168/jds.s0022-0302(91)78568-8

Cites

23 of 23 references verified0 citation errors · 0 not checkable

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Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Damage to the host from coliform mastitis is mediated by the release of endotoxin.

    “Damage to the host is mediated by the release of endotoxin.”

    From Coliform mastitis (2003) · cites this paper as [53]

  • Locally, endotoxin does not directly affect secretory cells but disrupts the blood flow.

    “Locally, endotoxin does not directly effect secretory cell but disrupts the blood flow [53].”

    From Coliform mastitis (2003) · cites this paper as [53]

Citations

Cites

Flagged first, then by citations

1 of the 24 references couldn’t be matched to a known paper.

Research works printed but not linked: 4

  1. Capuco, 1985, In vitro effect of bacterial toxins on lactating bovine mammary tissue, J. Dairy Sci., 68, 206
  2. Hatfield, 1985, The infusion of anti-inflammatory agents into udders with Escherichia coli endotoxin-induced inflammation, J. Dairy Sci., 68, 203
  3. Lefcourt, 1983, Radiotelemetry temperature responses of mammary gland and body to intramammary infusion of E. coli endotoxin S £. agalactiae in lactating dairy cows, J. Dairy Sci., 66, 214
  4. Sissoko, 1984, Lactose content of urine and milk from cows with sabclinical β-streptococcal mastitis, Dtsch. Tieraerztl. Wochenschr., 91, 151

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Metadata

Authors
Shuster, D. E., Harmon, R. J., Jackson, J. A., & Hemken, R. W.
Affiliations
University of Kentucky (US)
ORCID
Venue
Journal of Dairy Science
Publisher
American Dairy Science Association
Published
1991-11
Volume
74
Issue
11
Pages
3763-3774
ISSN
0022-0302 (ISSN-L)
DOI
10.3168/jds.s0022-0302(91)78568-8
OpenAlex
W1988955093
Cited by
143
References
24
Citations by year
2026: 1 · 2025: 5 · 2024: 3 · 2023: 4 · 2022: 3 · 2021: 8 · 2020: 6 · 2019: 4 · 2018: 4 · 2017: 14 · 2016: 6 · 2015: 6 · 2014: 8 · 2013: 7 · 2012: 3
FWCI
3.75
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Dairy Science (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Milk Quality and Mastitis in Dairy Cows
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Ruminant Nutrition and Digestive Physiology
  • Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal health and immunology
Keywords
mastitis, endotoxin, intramammary infusion, dairy cattle, milk composition, lactose, milk fat, milk protein, somatic cell count, N-acetyl-beta-D-glucosaminidase, lactoferrin, serum albumin, mammary gland inflammation, lactation performance, udder
MeSH terms
Acetylglucosaminidase, Animals, Blood Glucose, Cattle, Cell Count, Disease Models, Animal, Eating, Endotoxins, Female, Lactation Disorders, Lactoferrin, Lactose, Lipids, Mastitis, Bovine, Milk, Milk Proteins, Serum Albumin, Bovine

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