The DOI matches its Crossref record; 92 of the 92 references it cites were found in a registry or an index.
The extracellular matrix of the central and peripheral nervous systems: structure and function
Abstract
✓ The extracellular matrix (ECM) is the naturally occurring substrate upon which cells migrate, proliferate, and differentiate. The ECM functions as a biological adhesive that maintains the normal cytoarchitecture of different tissues and defines the key spatial relationships among dissimilar cell types. A loss of coordination and an alteration in the interactions between mesenchymal cells and epithelial cells separated by an ECM are thought to be fundamental steps in the development and progression of cancer. Although a substantial body of knowledge has been accumulated concerning the role of the ECM in most other tissues, much less is known of the structure and function of the ECM in the nervous system. Recent experiments in mammalian systems have shown that an increased knowledge of the ECM in the nervous system can lead to a better understanding of complex neurobiological processes under developmental, normal, and pathological conditions. This review focuses on the structure and function of the ECM in the peripheral and central nervous systems and on the importance of ECM macromolecules in axonal regeneration, cerebral edema, and cerebral neoplasia.
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Cites
Integrins: A family of cell surface receptors
HYNES, R. (1987) · Cell · doi:10.1016/0092-8674(87)90233-9 · Cited by 4,249
Roberts, A. B., Sporn, M. B., Assoian, R. K., Smith, J. M., Roche, N. S., Wakefield, L. M., Heine, U. I., Liotta, L. A., Falanga, V, & Kehrl, J. H. (1986) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.83.12.4167 · Cited by 2,866
Ignotz, R. A., & Massagué, J. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)35666-1 · Cited by 2,492
Metastatic potential correlates with enzymatic degradation of basement membrane collagen
Liotta, L. A., Tryggvason, K., Garbisa, S., Hart, I., Foltz, C. M., & Shafie, S. (1980) · Nature · doi:10.1038/284067a0 · Cited by 1,768
Arg-Gly-Asp: A versatile cell recognition signal
Ruoslahti, E., & Pierschbacher, M. D. (1986) · Cell · doi:10.1016/0092-8674(86)90259-x · Cited by 1,397
Role of collagenous matrices in the adhesion and growth of cells.
Kleinman, H. K., Klebe, R. J., & Martin, G. R. (1981) · The Journal of cell biology · doi:10.1083/jcb.88.3.473 · Cited by 1,361
Fibronectins: multifunctional modular glycoproteins.
Hynes, R. O., & Yamada, K. M. (1982) · The Journal of cell biology · doi:10.1083/jcb.95.2.369 · Cited by 1,326
Neuronal migration, with special reference to developing human brain: a review
Sidman, R. L., & Rakic, P. (1973) · Brain Research · doi:10.1016/0006-8993(73)90617-3 · Cited by 1,255
CELL SURFACE INTERACTIONS WITH EXTRACELLULAR MATERIALS
Yamada, K. M. (1983) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.52.070183.003553 · Cited by 1,135
Todaro, G. J., Fryling, C., & De Larco, J. E. (1980) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.77.9.5258 · Cited by 893
Cited by
Cost of Migration: Invasion of Malignant Gliomas and Implications for Treatment
Giese, A., Bjerkvig, R., Berens, M. E., & Westphal, M. (2003) · Journal of Clinical Oncology · doi:10.1200/jco.2003.05.063 · Cited by 1,200
Molecular mechanisms of glioma invasiveness: the role of proteases
Rao, J. S. (2003) · Nature Reviews Cancer · doi:10.1038/nrc1121 · Cited by 847
Lecticans: organizers of the brain extracellular matrix
Yamaguchi, Y. (2000) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000690 · Cited by 642
Ruoslahti, E. (1996) · Glycobiology · doi:10.1093/glycob/6.5.489 · Cited by 467
Extracellular matrix of the central nervous system: from neglect to challenge
Zimmermann, D. R., & Dours-Zimmermann, M. T. (2008) · Histochemistry and Cell Biology · doi:10.1007/s00418-008-0485-9 · Cited by 465
Metadata
- Authors
- Rutka, J. T., Apodaca, G., Stern, R., & Rosenblum, M.
- Venue
- Journal of Neurosurgery
- Published
- 1988-08
- Volume
- 69
- Issue
- 2
- Pages
- 155-170
- ISSN
- 0022-3085 (ISSN-L)
- OpenAlex
- W2071684114
- Cited by
- 310
- References
- 92
- FWCI
- 2.25
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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