Treatment of Benign Thyroid Nodules: Comparison of Surgery with Radiofrequency Ablation
Open accessAbstract
BACKGROUND AND PURPOSE: Nodular goiter is one of the most common benign lesions in thyroid nodule. The main treatment of the disease is still the traditional surgical resection, however there are many problems such as general anesthesia, surgical scar, postoperative thyroid or parathyroid function abnormalities, and high nodules recurrence rate in residual gland. The purpose of this study was to compare the efficacy, safety, and cost-effectiveness of 2 treatment methods, surgery and radiofrequency ablation, for the treatment of benign thyroid nodules. MATERIALS AND METHODS: From May 2012 to September 2013, 200 patients with nodular goiters who underwent surgery (group A) and 200 patients treated by radiofrequency ablation (group B) were enrolled in this study. Inclusion criteria were the following: 1) cosmetic problem, 2) nodule-related symptoms, 3) hyperfunctioning nodules related to thyrotoxicosis, and 4) refusal of surgery (for group B). An internally cooled radiofrequency ablation system and an 18-ga internally cooled electrode were used. We compared the 2 groups in terms of efficacy, safety, and cost-effectiveness during a 1-year follow-up. RESULTS: After radiofrequency ablation, the nodule volume decreased significantly from 5.4 to 0.4 mL (P = .002) at the 12-month follow-up. The incidence of complications was significantly higher from surgery than from radiofrequency ablation (6.0% versus 1.0%, P = .002). Hypothyroidism was detected in 71.5% of patients after surgery but in none following radiofrequency ablation. The rate of residual nodules (11.9% versus 2.9%, P = .004) and hospitalization days was significantly greater after surgery (6.6 versus 2.1 days, P < .001), but the cost difference was not significant. CONCLUSIONS: Surgical resection and radiofrequency ablation are both effective treatments of nodular goiter. Compared with surgery, the advantages of radiofrequency ablation include fewer complications, preservation of thyroid function, and fewer hospitalization days. Therefore, radiofrequency ablation should be considered a first-line treatment for benign thyroid nodules.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
A Korean study comparing RFA to surgery for nontoxic nodules found RFA was associated with an 85% reduction in nodule size, similar cost to surgery, fewer complications (RLN injury or hypoparathyroidism: 6% for surgery and 1% for RFA), and no patient who received RFA became hypothyroid.
“A Korean study compared the use of RFA to surgery for nontoxic nodules (306).RFA was associated with an 85% reduction in nodule size, the cost was similar to surgery, there were fewer complications (RLN injury or hypoparathyroidism: 6% for surgery and 1% for RFA), and no patient who received RFA became hypothyroid (306).”
From 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis (2016) · cites this paper as [306]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Cooper, D. S., Doherty, G. M., Haugen, B. R., Kloos, R. T., Lee, S. L., Mandel, S. J., Mazzaferri, E. L., McIver, B., Pacini, F., Schlumberger, M., et al. (2009) · Thyroid · doi:10.1089/thy.2009.0110 · Cited by 6,707 · see citing works
Gharib, H., Papini, E., Paschke, R., Duick, D. S., Valcavi, R., Hegedűs, L. D., Vitti, P., Gharib, H., Papini, E., Paschke, R., et al. (2010) · Endocrine Practice · doi:10.4158/10024.gl · Cited by 1,087 · see citing works
Radiofrequency ablation of benign thyroid nodules: safety and imaging follow-up in 236 patients
Jeong, W. K., Baek, J. H., Rhim, H., Kim, Y. S., Kwak, M. S., Jeong, H. J., & Lee, D. (2008) · European Radiology · doi:10.1007/s00330-008-0880-6 · Cited by 474 · see citing works
Self-citationMoon, W., Baek, J. H., Jung, S. L., Kim, D. W., Kim, E., Kim, J. Y., Kwak, J. Y., Lee, J. H., Lee, J., Lee, Y. H., et al. (2011) · Korean Journal of Radiology · doi:10.3348/kjr.2011.12.1.1 · Cited by 474 · see citing works
Self-citationTotal Thyroidectomy Plus Neck Dissection in Differentiated Papillary Thyroid Carcinoma Patients
Roh, J., Park, J., & Park, C. I. (2007) · Annals of Surgery · doi:10.1097/01.sla.0000250451.59685.67 · Cited by 400 · see citing works
Baek, J. H., Lee, J. H., Sung, J. Y., Bae, J.-I., Kim, K. T., Sim, J., Baek, S. M., Kim, Y., Shin, J. H., Park, J. S., et al. (2011) · Radiology · doi:10.1148/radiol.11110416 · Cited by 388 · see citing works
Self-citationNa, D. G., Lee, J. H., Jung, S. L., Kim, J., Sung, J. Y., Shin, J. H., Kim, E., Lee, J., Kim, D. W., Park, J. S., et al. (2012) · Korean Journal of Radiology · doi:10.3348/kjr.2012.13.2.117 · Cited by 339 · see citing works
Self-citationLim, H. K., Lee, J. H., Ha, E. J., Sung, J. Y., Kim, T. Y., & Baek, J. H. (2012) · European Radiology · doi:10.1007/s00330-012-2671-3 · Cited by 333 · see citing works
Self-citationSpiezia, S., Garberoglio, R., Milone, F., Ramundo, V., Caiazzo, C., Assanti, A. P., Deandrea, M., Limone, P. P., Macchia, P. E., Lombardi, G., et al. (2009) · Thyroid · doi:10.1089/thy.2008.0202 · Cited by 279 · see citing works
Recurrent laryngeal nerve injury in thyroid surgery: a review
Hayward, N. J., Grodski, S., Yeung, M. J., Johnson, W. R., & Serpell, J. W. (2012) · ANZ Journal of Surgery · doi:10.1111/j.1445-2197.2012.06247.x · Cited by 263 · see citing works
Nonsurgical, Image-Guided, Minimally Invasive Therapy for Thyroid Nodules
Gharib, H., Hegedűs, L. D., Pacella, C. M., Baek, J. H., & Papini, E. (2013) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-1806 · Cited by 253 · see citing works
Self-citationRadiofrequency ablation of regional recurrence from well-differentiated thyroid malignancy
Dupuy, D. E., Monchik, J. M., Decrea, C., & Pisharodi, L. R. (2001) · Surgery · doi:10.1067/msy.2001.118708 · Cited by 238 · see citing works
Radiofrequency Ablation for the Treatment of Autonomously Functioning Thyroid Nodules
Baek, J. H., Moon, W., Kim, Y. S., Lee, J. H., & Lee, D. (2009) · World Journal of Surgery · doi:10.1007/s00268-009-0130-3 · Cited by 234 · see citing works
Self-citationQuality Improvement Guidelines for Percutaneous Transhepatic Cholangiography and Biliary Drainage
Burke, D. R., Lewis, C. A., Cardella, J. F., Citron, S. J., Drooz, A. T., Haskal, Z. J., Husted, J. W., McCowan, T. C., Moore, A. V., Oglevie, S. B., et al. (1997) · Journal of Vascular and Interventional Radiology · doi:10.1016/s1051-0443(97)70630-4 · Cited by 209 · see citing works
Sung, J. Y., Baek, J. H., Kim, K. S., Lee, D., Yoo, H., Kim, T. Y., & Park, S. H. (2013) · Radiology · doi:10.1148/radiol.13122134 · Cited by 187 · see citing works
Self-citationBaek, J. H., Kim, Y. S., Sung, J. Y., Choi, H. S., & Lee, J. H. (2011) · American Journal of Roentgenology · doi:10.2214/ajr.10.5345 · Cited by 165 · see citing works
Self-citationPapini, E., Rago, T., Gambelunghe, G., Valcavi, R., Bizzarri, G., Vitti, P., Feo, P. D., Riganti, F., Misischi, I., Stasio, E. D., et al. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-1826 · Cited by 163 · see citing works
Radiofrequency Ablation Compared to Surgery for the Treatment of Benign Thyroid Nodules
Bernardi, S., Dobrinja, C., Fabris, B., Bazzocchi, G., Sabato, N., Ulcigrai, V., Giacca, M., Barro, E., de Manzini, N., & Stacul, F. (2014) · International Journal of Endocrinology · doi:10.1155/2014/934595 · Cited by 161 · see citing works
Radiofrequency Ablation of Thyroid Nodules: Basic Principles and Clinical Application
Shin, J. H., Baek, J. H., Ha, E. J., & Lee, J. H. (2012) · International Journal of Endocrinology · doi:10.1155/2012/919650 · Cited by 157 · see citing works
Self-citationKwak, J. Y., Jung, I., Baek, J. H., Baek, S. M., Choi, N., Choi, Y. J., Jung, S. L., Kim, E., Kim, J., Kim, J., et al. (2013) · Korean Journal of Radiology · doi:10.3348/kjr.2013.14.1.110 · Cited by 151 · see citing works
Self-citationFeng, B. C., Liang, P., Cheng, Z., Yu, X., Yu, J., Han, Z., & Liu, F. (2012) · European Journal of Endocrinology · doi:10.1530/eje-11-0966 · Cited by 151 · see citing works
Sun, G. H., Peress, L., & Pynnonen, M. A. (2014) · Otolaryngology · doi:10.1177/0194599814521779 · Cited by 139 · see citing works
Lim, H. K., Baek, J. H., Lee, J. H., Kim, W. B., Kim, T. Y., Shong, Y. K., & Hong, S. J. (2014) · European Radiology · doi:10.1007/s00330-014-3405-5 · Cited by 133 · see citing works
Self-citationThyroid Nodules Treated with Percutaneous Radiofrequency Thermal Ablation: A Comparative Study
Faggiano, A., Ramundo, V., Assanti, A. P., Fonderico, F., Macchia, P. E., Misso, C., Marciello, F., Marotta, V., Prete, M. D., Papini, E., et al. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-2251 · Cited by 122 · see citing works
Postauricular and Axillary Approach Endoscopic Neck Surgery: A New Technique
Lee, K. E., Kim, H. Y., Park, W. S., Choe, J., Kwon, M. R., Oh, S. K., & Youn, Y. (2009) · World Journal of Surgery · doi:10.1007/s00268-009-9922-8 · Cited by 110 · see citing works
Radiofrequency and ethanol ablation for the treatment of recurrent thyroid cancers
Shin, J. E., Baek, J. H., & Lee, J. H. (2012) · Current Opinion in Oncology · doi:10.1097/cco.0b013e32835a583d · Cited by 96 · see citing works
Self-citationHa, E. J., Baek, J. H., & Lee, J. H. (2014) · Korean Journal of Radiology · doi:10.3348/kjr.2014.15.6.836 · Cited by 93 · see citing works
Self-citationUrken, M. L., Milas, M., Randolph, G. W., Tufano, R. P., Bergman, D. A., Bernet, V. J., Brett, E. M., Brierley, J. D., Cobin, R. H., Doherty, G. M., et al. (2014) · Head & Neck · doi:10.1002/hed.23615 · Cited by 88 · see citing works
Papini, E., Pacella, C. M., & Hegedűs, L. D. (2014) · European Journal of Endocrinology · doi:10.1530/eje-13-0917 · Cited by 84 · see citing works
Radiofrequency ablation for treatment of benign thyroid nodules: Systematic review
Fuller, C. W., Nguyen, S. A., Lohia, S., & Gillespie, M. B. (2013) · The Laryngoscope · doi:10.1002/lary.24406 · Cited by 71 · see citing works
Gibelin, H., Sierra, M., Mothes, D., Ingrand, P., Levillain, P., Jones, C., Hadjadj, S., Torremocha, F., Maréchaud, R., Barbier, J., et al. (2004) · World Journal of Surgery · doi:10.1007/s00268-004-7607-x · Cited by 65 · see citing works
Advances in Nonsurgical Treatment of Benign Thyroid Nodules
Ha, E. J., & Baek, J. H. (2014) · Future Oncology · doi:10.2217/fon.14.59 · Cited by 25 · see citing works
Self-citationSurgical therapeutic planning options in nodular goiter.
Pelizzo, M. R., Boschin, I. M., Toniato, A., Sorgato, N., Marzola, M. C., & Rubello, D. (2010) · PubMed · Cited by 17 · see citing works
Shin, J. H., Baek, J. H., Oh, Y., Ha, E. J., & Lee, J. H. (2013) · Korean Journal of Radiology · doi:10.3348/kjr.2013.14.5.805 · Cited by 5 · see citing works
Self-citation
Flagged first, then by citations
Research works printed but not linked: 2
- Cooper DS, Doherty GM, Haugen BR, et al. Revised American Thy- roid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer. Thyroid 2009;19: 1167-214
- Ha EJ, Baek JH, Lee JH. Moving-shot versus fixed electrode tech- niques used for radiofrequency ablation: an experimental compar- ison in an ex-vivo bovine liver tissue model. Korean J Radiol 2014;15:836 -43
Cited by
Sorted by citations
Ross, D. S., Burch, H. B., Cooper, D. S., Greenlee, M. C., Laurberg, P., Maia, A. L., Rivkees, S. A., Samuels, M., Sosa, J. A., Stan, M. N., et al. (2016) · Thyroid® · doi:10.1089/thy.2016.0229 · Cited by 2,938 · see citing works
“RFA was associated with an 85% reduction in nodule size, the cost was similar to surgery, there were fewer complications (RLN injury or hypoparathyroidism: 6% for surgery and 1% for RFA), and no patient who received RFA became hypothyroid (306).”
Method2017 Thyroid Radiofrequency Ablation Guideline: Korean Society of Thyroid Radiology
Kim, J., Baek, J. H., Lim, H. K., Ahn, H. S., Baek, S. M., Choi, Y. J., Choi, Y. J., Chung, S. R., Ha, E. J., Hahn, S. Y., et al. (2018) · Korean Journal of Radiology · doi:10.3348/kjr.2018.19.4.632 · Cited by 663 · see citing works
Self-citationOrloff, L. A., Noel, J. E., Stack, B. C., Russell, M. D., Angelos, P., Baek, J. H., Brumund, K. T., Chiang, F., Cunnane, M. B., Davies, L., et al. (2021) · Head & Neck · doi:10.1002/hed.26960 · Cited by 320 · see citing works
Self-citationJung, S. L., Baek, J. H., Lee, J. H., Shong, Y. K., Sung, J. Y., Kim, K. S., Lee, D., Kim, J., Baek, S. M., Sim, J. S., et al. (2018) · Korean Journal of Radiology · doi:10.3348/kjr.2018.19.1.167 · Cited by 214 · see citing works
Self-citationPapini, E., Pacella, C. M., Solbiati, L., Achille, G., Barbaro, D., Bernardi, S., Cantisani, V., Cesareo, R., Chiti, A., Cozzaglio, L., et al. (2019) · International Journal of Hyperthermia · doi:10.1080/02656736.2019.1575482 · Cited by 199 · see citing works
Chung, S. R., Suh, C. H., Baek, J. H., Park, H. S., Choi, Y. J., & Lee, J. H. (2017) · International Journal of Hyperthermia · doi:10.1080/02656736.2017.1337936 · Cited by 191 · see citing works
Self-citationHahn, S. Y., Shin, J. H., Na, D. G., Ha, E. J., Ahn, H. S., Lim, H. K., Lee, J. H., Park, J. S., Kim, J., Sung, J. Y., et al. (2019) · Korean Journal of Radiology · doi:10.3348/kjr.2018.0696 · Cited by 179 · see citing works
Self-citationKim, C., Lee, J. H., Choi, Y. J., Kim, W. B., Sung, T., & Baek, J. H. (2016) · European Radiology · doi:10.1007/s00330-016-4690-y · Cited by 169 · see citing works
Self-citationSinclair, C. F., Baek, J. H., Hands, K. E., Hodak, S. P., Huber, T. C., Hussain, I., Lang, B. H., Noel, J. E., Papaleontiou, M., Patel, K. N., et al. (2023) · Thyroid · doi:10.1089/thy.2023.0281 · Cited by 140 · see citing works
Self-citationImage-guided thermal ablation of benign thyroid nodules
Mainini, A. P., Monaco, C. G., Pescatori, L., Angelis, C. D., Sardanelli, F., Sconfienza, L. M., & Mauri, G. (2016) · Journal of Ultrasound · doi:10.1007/s40477-016-0221-6 · Cited by 108 · see citing works
Monopolar Radiofrequency Ablation of Thyroid Nodules: A Prospective Austrian Single-Center Study
Dobnig, H., & Amrein, K. (2018) · Thyroid · doi:10.1089/thy.2017.0547 · Cited by 106 · see citing works
Dietrich, C. F., Müller, T., Bojunga, J., Dong, Y., Mauri, G., Radziņa, M., Dighe, M., Cui, X., Grünwald, F., Schüler, A., et al. (2017) · Ultrasound in Medicine & Biology · doi:10.1016/j.ultrasmedbio.2017.08.1889 · Cited by 101 · see citing works
Tufano, R. P., Pace‐Asciak, P., Russell, J. O., Suarez, C. M., Randolph, G. W., López, F., Shaha, A. R., Mäkitie, A. A., Rodrigo, J. P., Kowalski, L. P., et al. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.698689 · Cited by 97 · see citing works
Complications Following Radiofrequency Ablation of Benign Thyroid Nodules: A Systematic Review
Wang, J.-F., Wu, T., Hu, K.-P., Xu, W., Zheng, B.-W., Tong, G., Yao, Z.-C., Liu, B., & Ren, J. (2017) · Chinese Medical Journal · doi:10.4103/0366-6999.206347 · Cited by 93 · see citing works
Radiofrequency ablation and thyroid nodules: updated systematic review
Muhammad, H., Santhanam, P., & Russell, J. O. (2021) · Endocrine · doi:10.1007/s12020-020-02598-6 · Cited by 93 · see citing works
Li, J., Liu, Y., Liu, J., & Qian, L. (2018) · International Journal of Hyperthermia · doi:10.1080/02656736.2018.1453092 · Cited by 89 · see citing works
Yue, W., Wang, S., Lu, F., Li, X., Xu, H., Sun, L., Guo, L., He, Y., Wang, D., & Yin, Z. (2016) · Scientific Reports · doi:10.1038/srep37838 · Cited by 89 · see citing works
Cesareo, R., Naciu, A. M., Iozzino, M., Pasqualini, V., Simeoni, C., Casini, A., Campagna, G., Manfrini, S., Tabacco, G., & Palermo, A. (2018) · International Journal of Hyperthermia · doi:10.1080/02656736.2018.1430868 · Cited by 84 · see citing works
Management strategy for nerve damage during radiofrequency ablation of thyroid nodules
Chung, S. R., Baek, J. H., Choi, Y. J., & Lee, J. H. (2019) · International Journal of Hyperthermia · doi:10.1080/02656736.2018.1554826 · Cited by 81 · see citing works
Self-citation12-month efficacy of a single radiofrequency ablation on autonomously functioning thyroid nodules
Bernardi, S., Stacul, F., Michelli, A., Giudici, F., Zuolo, G., de Manzini, N., Dobrinja, C., Zanconati, F., & Fabris, B. (2016) · Endocrine · doi:10.1007/s12020-016-1174-4 · Cited by 81 · see citing works
Ha, E. J., Baek, J. H., Che, Y., Chou, Y., Fukunari, N., Kim, J., Lin, W., My, L. T., Na, D. G., Quek, L. H. H., et al. (2020) · ULTRASONOGRAPHY · doi:10.14366/usg.20112 · Cited by 80 · see citing works
Self-citationRadiofrequency ablation of thyroid nodules: “Good Clinical Practice Recommendations” for Austria
Dobnig, H., Zechmann, W., Hermann, M., Lehner, M., Heute, D., Mirzaei, S., Gessl, A., Stepan, V., Höfle, G., Riss, P., et al. (2019) · Wiener Medizinische Wochenschrift · doi:10.1007/s10354-019-0682-2 · Cited by 78 · see citing works
Wang, B., Han, Z., Yu, J., Cheng, Z., Liu, F., Yu, X., Chen, C.-N., Liu, J., & Liang, P. (2017) · International Journal of Hyperthermia · doi:10.1080/02656736.2016.1274058 · Cited by 76 · see citing works
Hamidi, O., Callstrom, M. R., Lee, R. A., Dean, D. S., Castro, M. R., Morris, J. C., & Stan, M. N. (2018) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2017.12.011 · Cited by 72 · see citing works
Risk Assessment and Hydrodissection Technique for Radiofrequency Ablation of Thyroid Benign Nodules
Xiaoyin, T., Li, P., Dan, C., Min, D., Jiachang, C., Tao, W., Yaoping, S., Wang, Z., & Zhai, B. (2018) · Journal of Cancer · doi:10.7150/jca.26060 · Cited by 71 · see citing works
Laser and radiofrequency ablations for benign and malignant thyroid tumors
Mauri, G., Gennaro, N., Lee, M. K., & Baek, J. H. (2019) · International Journal of Hyperthermia · doi:10.1080/02656736.2019.1622795 · Cited by 69 · see citing works
Self-citationUS-guided percutaneous microwave ablation for the treatment of benign thyroid nodules
Wu, W., Gong, X., Zhou, Q., Chen, X., Chen, X., & Shi, B. (2017) · Endocrine Journal · doi:10.1507/endocrj.ej17-0152 · Cited by 61 · see citing works
Percutaneous laser ablation for benign and malignant thyroid diseases
Mauri, G., Nicosia, L., Vigna, P. D., Varano, G. M., Maiettini, D., Bonomo, G., Giuliano, G., Orsi, F., Solbiati, L., Fiori, E. D., et al. (2018) · ULTRASONOGRAPHY · doi:10.14366/usg.18034 · Cited by 60 · see citing works
Cesareo, R., Palermo, A., Pasqualini, V., Cianni, R., Gaspa, G., Manfrini, S., & Pacella, C. M. (2017) · Clinical Endocrinology · doi:10.1111/cen.13422 · Cited by 58 · see citing works
Kim, H. J., Cho, S. J., Baek, J. H., & Suh, C. H. (2020) · European Radiology · doi:10.1007/s00330-020-07166-0 · Cited by 56 · see citing works
Self-citationThyroid Nodule Radiofrequency Ablation: Complications and Clinical Follow Up
Lim, J. Y., & Kuo, J. H. (2022) · Techniques in vascular and interventional radiology · doi:10.1016/j.tvir.2022.100824 · Cited by 54 · see citing works
Cesareo, R., Palermo, A., Pasqualini, V., Manfrini, S., Trimboli, P., Stacul, F., Fabris, B., & Bernardi, S. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00317 · Cited by 53 · see citing works
Jasim, S., Patel, K. N., Randolph, G. W., Adams, S., Cesareo, R., Condon, E., Henrichsen, T. L., Itani, M., Papaleontiou, M., Rangel, L. G., et al. (2022) · Endocrine Practice · doi:10.1016/j.eprac.2022.02.011 · Cited by 55 · see citing works
Radiofrequency Ablation of Benign and Malignant Thyroid Nodules
Navin, P. J., Thompson, S. M., Kurup, A. N., Lee, R. A., Callstrom, M. R., Castro, M. R., Stan, M. N., Welch, B. T., & Schmitz, J. J. (2022) · Radiographics · doi:10.1148/rg.220021 · Cited by 52 · see citing works
Cervelli, R., Mazzeo, S., Boni, G., Boccuzzi, A., Bianchi, F., Brozzi, F., Santini, P., Vitti, P., Cioni, R., & Caramella, D. (2019) · Clinical Endocrinology · doi:10.1111/cen.13938 · Cited by 50 · see citing works
Hamou, A. B., Ghanassia, É., Espiard, S., Rached, H. A., Jannin, A., Correas, J. M., Cao, C. D., Kyheng, M., Vantyghem, M., & Monpeyssen, H. (2019) · International Journal of Hyperthermia · doi:10.1080/02656736.2019.1627432 · Cited by 50 · see citing works
Nixon, I. J., Angelos, P., Shaha, A. R., Rinaldo, A., Williams, M. D., & Ferlito, A. (2018) · Head & Neck · doi:10.1002/hed.25181 · Cited by 48 · see citing works
Chung, J. I., Lee, Y. J., Choi, Y. J., Ha, E. J., Suh, C. H., Choi, M., Baek, J. H., Na, D. G., Korean Society of Thyroid Radiology (KSThR), & Korean Society of Radiology (2020) · ULTRASONOGRAPHY · doi:10.14366/usg.20072 · Cited by 48 · see citing works
Self-citationGuang, Y., He, W., Luo, Y., Zhang, H., Zhang, Y., Ning, B., & Yu, T. (2019) · BMC Cancer · doi:10.1186/s12885-019-5338-5 · Cited by 47 · see citing works
Negro, R., Greco, G., Deandrea, M., Rucco, M., & Trimboli, P. (2020) · Korean Journal of Radiology · doi:10.3348/kjr.2019.0798 · Cited by 47 · see citing works
Guan, S., Wang, H., & Teng, D. (2020) · International Journal of Hyperthermia · doi:10.1080/02656736.2020.1758802 · Cited by 46 · see citing works
Shen, K., Xue, S., Xie, Y., Wang, H., Li, J., Sun, Y., Wang, K., Xu, G., Guo, T., Fan, B., et al. (2020) · International Journal of Hyperthermia · doi:10.1080/02656736.2020.1777331 · Cited by 46 · see citing works
A single session of laser ablation for toxic thyroid nodules: three-year follow-up results
Gambelunghe, G., Stefanetti, E., Colella, R., Monacelli, M., Avenia, N., & Feo, P. D. (2018) · International Journal of Hyperthermia · doi:10.1080/02656736.2018.1437931 · Cited by 45 · see citing works
Patient satisfaction after thyroid RFA versus surgery for benign thyroid nodules: a telephone survey
Bernardi, S., Dobrinja, C., Carere, A., Giudici, F., Calabrò, V., Zanconati, F., de Manzini, N., Fabris, B., & Stacul, F. (2018) · International Journal of Hyperthermia · doi:10.1080/02656736.2018.1487590 · Cited by 45 · see citing works
Jin, H., Fan, J., Liao, K. T., He, Z., Li, W., & Cui, M. (2018) · International Journal of Hyperthermia · doi:10.1080/02656736.2018.1492028 · Cited by 44 · see citing works
Chung, S. R., Baek, J. H., Sung, J. Y., Ryu, J. H., & Jung, S. L. (2019) · Endocrinology and Metabolism · doi:10.3803/enm.2019.34.4.415 · Cited by 41 · see citing works
Self-citationRFA and benign thyroid nodules: Review of the current literature
Muhammad, H., Santhanam, P., Russell, J. O., & Kuo, J. H. (2021) · Laryngoscope Investigative Otolaryngology · doi:10.1002/lio2.517 · Cited by 39 · see citing works
Radiofrequency ablation for benign thyroid nodules
Bernardi, S., Stacul, F., Zecchin, M., Dobrinja, C., Zanconati, F., & Fabris, B. (2016) · Journal of Endocrinological Investigation · doi:10.1007/s40618-016-0469-x · Cited by 38 · see citing works
Cesareo, R., Palermo, A., Pasqualini, V., Simeoni, C., Casini, A., Pelle, G., Manfrini, S., Campagna, G., & Cianni, R. (2017) · Archives of Endocrinology and Metabolism · doi:10.1590/2359-3997000000246 · Cited by 38 · see citing works
Ethanol Ablation for the Treatment of Cystic and Predominantly Cystic Thyroid Nodules
Iñiguez‐Ariza, N. M., Lee, R. A., Ospina, N. S., Stan, M. N., & Castro, M. R. (2018) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2018.05.020 · Cited by 37 · see citing works
Zhang, C., Yin, J., Hu, C., Ye, Q., Wang, P., & Huang, P. (2021) · Clinical Hemorheology and Microcirculation · doi:10.3233/ch-201087 · Cited by 37 · see citing works
Wu, W., Gong, X., Zhou, Q., Chen, X., & Chen, X. (2017) · International Journal of Endocrinology · doi:10.1155/2017/9724090 · Cited by 36 · see citing works
Radiofrequency Ablation for Benign Thyroid Nodules: 1‐Year Follow‐Up in 184 Patients
Vuong, N. L., Đình, L. Q., Bằng, H. T., Thuy, T. T. M., Bắc, N. H., & Vỹ, T. T. (2019) · World Journal of Surgery · doi:10.1007/s00268-019-05044-5 · Cited by 35 · see citing works
Song, Q., Gao, H., Ren, L., Tian, X., Lan, Y., Yan, L., & Luo, Y. (2021) · International Journal of Hyperthermia · doi:10.1080/02656736.2021.1916625 · Cited by 35 · see citing works
Chen, S., Dou, J., Cang, Y., Che, Y., Dong, G., Zhang, C., Xu, D. M., Long, Q., Yu, J., & Liang, P. (2024) · Radiology · doi:10.1148/radiol.232162 · Cited by 33 · see citing works
Self-citationEvaluation of the safety and efficacy of radiofrequency ablation for treating benign thyroid nodules
Xiaoyin, T., Cui, D., Chi, J., Wang, Z., Wang, T., Zhai, B., & Li, P. (2017) · Journal of Cancer · doi:10.7150/jca.17655 · Cited by 33 · see citing works
Negro, R., Rucco, M., Creanza, A., Mormile, A., Limone, P. P., Garberoglio, R., Spiezia, S., Monti, S., Cugini, C., Dalati, G. E., et al. (2019) · European Thyroid Journal · doi:10.1159/000504882 · Cited by 32 · see citing works
Wang, N., Zheng, B., Wu, T., Tan, L., Lian, Y., Ma, Y., Guo, R., Xu, S., Zeng, L., Xu, W., et al. (2021) · International Journal of Hyperthermia · doi:10.1080/02656736.2021.1950849 · Cited by 31 · see citing works
Korkusuz, H., Wolf, T., & Grünwald, F. (2018) · International Journal of Hyperthermia · doi:10.1080/02656736.2018.1453552 · Cited by 31 · see citing works
Lang, B. H., Wong, C. K. H., Ma, E., Woo, Y. C., & Chiu, K. W.-H. (2018) · Surgery · doi:10.1016/j.surg.2018.05.080 · Cited by 31 · see citing works
Radiofrequency Ablation of Benign Thyroid Nodules
Ha, E. J., Baek, J. H., Che, Y., Chou, Y., Fukunari, N., Kim, J., Lin, W., My, L. T., Na, D. G., Quek, L. H. H., et al. (2021) · Journal of Medical Ultrasound · doi:10.4103/jmu.jmu_178_20 · Cited by 31 · see citing works
Self-citationBo, X., Lu, F., Yu, S.-Y., Yue, W., Li, X., Hu, M., Wu, L., Lv, Z., Sun, L., & Xu, H. (2022) · International Journal of Hyperthermia · doi:10.1080/02656736.2022.2040608 · Cited by 31 · see citing works
Russell, J. O., Desai, D. D., Noel, J. E., Hussein, M. H., Toraih, E. A., Seo, S., Wolfe, S. A., Omar, M., Issa, P. P., Orloff, L. A., et al. (2023) · Surgery · doi:10.1016/j.surg.2023.07.046 · Cited by 30 · see citing works
Yan, J., Qiu, T., Lu, J., Wu, Y., & Yang, Y. (2018) · International Journal of Hyperthermia · doi:10.1080/02656736.2018.1427286 · Cited by 30 · see citing works
Kuo, J. H., Sinclair, C. F., Lang, B. H., Spiezia, S., Yu, M.-A., Ha, E. J., Na, D. G., Offi, C., Patel, K. N., & Baek, J. H. (2021) · Surgery · doi:10.1016/j.surg.2021.07.043 · Cited by 30 · see citing works
Self-citationEfficacy of Microwave Ablation in the Treatment of Large (≥3 cm) Benign Thyroid Nodules
Khanh, H. Q., Hung, N. Q., Vũ, H. V., Khôi, N. V., & Vuong, N. L. (2020) · World Journal of Surgery · doi:10.1007/s00268-020-05432-2 · Cited by 29 · see citing works
Minimally Invasive Techniques for the Management of Thyroid Nodules
Baldwin, C. K., Natter, M., Patel, K. N., & Hodak, S. P. (2022) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/j.ecl.2022.01.001 · Cited by 29 · see citing works
Issa, P. P., Omar, M., Issa, C. P., Buti, Y. J., Hussein, M. H., Aboueisha, M. A., Abdelhady, A., Shama, M., Lee, G. S., Toraih, E. A., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911493 · Cited by 29 · see citing works
Chorti, A. G., Bontinis, V., Tzikos, G., Bontinis, A., Ioannidis, A., Michalopoulos, A., & Papavramidis, T. S. (2023) · Thyroid · doi:10.1089/thy.2022.0671 · Cited by 29 · see citing works
Radiofrequency ablation for treatment of benign thyroid nodules
Chen, F., Tian, G., Kong, D., Zhong, L., & Jiang, T. (2016) · Medicine · doi:10.1097/md.0000000000004659 · Cited by 29 · see citing works
Lin, W., Chen, W., Wang, P., Chan, Y., Chang, Y., Chen, H.-S., Chen, S., Chen, W., Cheng, K., Chi, S., et al. (2022) · ULTRASONOGRAPHY · doi:10.14366/usg.22126 · Cited by 28 · see citing works
Lang, B. H., Wong, C. K. H., & Ma, E. (2017) · International Journal of Hyperthermia · doi:10.1080/02656736.2017.1305127 · Cited by 27 · see citing works
Hong, M. J., Sung, J. Y., Baek, J. H., Je, M. S., Choi, D. W., Yoo, H., Yang, S. J., Nam, S. Y., & Yoo, E. Y. (2019) · Journal of Vascular and Interventional Radiology · doi:10.1016/j.jvir.2018.10.034 · Cited by 27 · see citing works
Self-citationCang, Y., Fan, F., Liu, Y., Li, J., Pang, C., Xu, D. M., Che, Y., Zhang, C., Dong, G., Liang, P., et al. (2024) · European Radiology · doi:10.1007/s00330-024-10614-w · Cited by 26 · see citing works
Self-citationTreatment of thyroid nodules with radiofrequency: a 1-year follow-up experience
Rabuffi, P., Spada, A., Bosco, D., Bruni, A. D. C., Vagnarelli, S., Ambrogi, C., Stasio, E. D., & Santonati, A. (2019) · Journal of Ultrasound · doi:10.1007/s40477-019-00375-4 · Cited by 26 · see citing works
Oddo, S., Felix, E., Mussap, M., & Giusti, M. (2018) · Korean Journal of Radiology · doi:10.3348/kjr.2018.19.1.175 · Cited by 26 · see citing works
Qian, Y., Li, Z., Fan, C., & Huang, Y. (2024) · Experimental Gerontology · doi:10.1016/j.exger.2024.112425 · Cited by 24 · see citing works
Nonsurgical Management of Thyroid Nodules: The Role of Ablative Therapies
Stan, M. N., Papaleontiou, M., Schmitz, J. J., & Castro, M. R. (2021) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgab917 · Cited by 24 · see citing works
Radiofrequency ablation of thyroid nodules: a clinical review of treatment complications
Issa, P. P., Cironi, K. A., Rezvani, L., & Kandil, E. H. (2024) · Gland Surgery · doi:10.21037/gs-22-539 · Cited by 24 · see citing works
Radiofrequency ablation and thyroid cancer: review of the current literature
Muhammad, H., Tehreem, A., & Russell, J. O. (2021) · American Journal of Otolaryngology · doi:10.1016/j.amjoto.2021.103204 · Cited by 23 · see citing works
Lui, M. S., & Patel, K. N. (2024) · Gland Surgery · doi:10.21037/gs-23-18 · Cited by 22 · see citing works
Kuo, T., Chen, K.-Y., Lai, C., Wang, Y., Lin, M., Chang, C., & Wu, M. (2024) · International Journal of Surgery · doi:10.1097/js9.0000000000001201 · Cited by 22 · see citing works
Lončar, I., van Dijk, S. P. J., van Velsen, E. F. S., Buijk, S. E., Niemeijer, N. D., Veeken, C. J., Meyenfeldt, E. M. V., Dinkelaar, W., Franssen, G. J. H., Peeters, R. P., et al. (2022) · Journal of Vascular and Interventional Radiology · doi:10.1016/j.jvir.2022.01.012 · Cited by 20 · see citing works
Mauri, G., Pacella, C. M., Papini, E., Sconfienza, L. M., & Solbiati, L. (2018) · International Journal of Hyperthermia · doi:10.1080/02656736.2018.1442590 · Cited by 20 · see citing works
Negro, R., & Trimboli, P. (2020) · Electromagnetic Biology and Medicine · doi:10.1080/15368378.2020.1809448 · Cited by 20 · see citing works
Xu, X., Peng, Y. H., & Han, G. (2023) · American Journal of Otolaryngology · doi:10.1016/j.amjoto.2023.104025 · Cited by 19 · see citing works
Efficacy on radiofrequency ablation according to the types of benign thyroid nodules
Li, J., Xue, W., Xu, P., Deng, Z., Duan, C., Zhang, D., Zheng, S., Cui, K., & Qiu, X. (2021) · Scientific Reports · doi:10.1038/s41598-021-01593-9 · Cited by 19 · see citing works
Chen, W., Luo, S., Chen, W., Chou, C., Chang, Y., Cheng, K., & Lin, W. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.776919 · Cited by 18 · see citing works
Miller, J. R., Tanavde, V. A., Razavi, C. R., Saraswathula, A., Russell, J. O., & Tufano, R. P. (2022) · Head & Neck · doi:10.1002/hed.27213 · Cited by 18 · see citing works
Comparison of Mono‐ and Bipolar Radiofrequency Ablation in Benign Thyroid Disease
Korkusuz, Y., Mader, A., Groener, D., Ahmad, S., Mader, O. M., Grünwald, F., & Happel, C. (2017) · World Journal of Surgery · doi:10.1007/s00268-017-4039-y · Cited by 18 · see citing works
Ding, Z., Chen, J., Chen, Z., Zeng, X., Zheng, P., Wang, X., Cui, X., & Sang, L. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.738299 · Cited by 18 · see citing works
Choice in Ablative Therapies for Thyroid Nodules
Hu, Q. L., & Kuo, J. H. (2023) · Journal of the Endocrine Society · doi:10.1210/jendso/bvad078 · Cited by 17 · see citing works
Novel Approaches for Treating Autonomously Functioning Thyroid Nodules
Pace‐Asciak, P., Russell, J. O., Shaear, M., & Tufano, R. P. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.565371 · Cited by 17 · see citing works
Thyroid Nodule Rupture Following Radiofrequency Ablation for Benign Thyroid Nodules
Austerlitz, J., Mann, D., Noel, J. E., & Orloff, L. A. (2024) · JAMA Otolaryngology–Head & Neck Surgery · doi:10.1001/jamaoto.2024.1400 · Cited by 16 · see citing works
Chiang, P., Lin, W., Chen, H.-L., Luo, S., Chen, M., Chen, W., Chang, Y.-H., Chou, C., Su, Y.-Y., Tung, Y.-C., et al. (2021) · International Journal of Hyperthermia · doi:10.1080/02656736.2021.1942241 · Cited by 15 · see citing works
Self-citationUltrasound‐Guided Percutaneous Microwave Ablation for Substernal Goiter: Initial Experience
Cui, R., Yu, J., Han, Z., Liu, F., Yu, X., & Liang, P. (2019) · Journal of Ultrasound in Medicine · doi:10.1002/jum.14992 · Cited by 14 · see citing works
Wang, M., Liu, X., Wang, Q., & Zhang, H. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.952113 · Cited by 14 · see citing works
Yan, L., Li, X., Li, Y., & Luo, Y. (2023) · American Journal of Neuroradiology · doi:10.3174/ajnr.a7890 · Cited by 13 · see citing works
Self-citationNtelis, S., & Linos, D. A. (2021) · HORMONES · doi:10.1007/s42000-021-00283-5 · Cited by 13 · see citing works
Nguyễn, V. B., Nguyen, T. X., Nguyen, V. V. H., Nguyen, H. N., Nguyen, D. T., & Le, C. V. (2021) · International Journal of Endocrinology · doi:10.1155/2021/7556393 · Cited by 13 · see citing works
- Authors
- Che, Y., Jin, S., Shi, C., Wang, L., Zhang, X., Li, Y., & Baek, J. H.
- Affiliations
- First Affiliated Hospital of Dalian Medical University (CN)
- Dalian Medical University (CN)
- Asan Medical Center (KR)
- Venue
- American Journal of Neuroradiology
- Published
- 2015-03-26
- Volume
- 36
- Issue
- 7
- Pages
- 1321-1325
- ISSN
- 0195-6108 (ISSN-L)
- 1936-959X
- PMC
- PMC7965284
- OpenAlex
- W2034580160
- Cited by
- 205
- References
- 34
- Citations by year
- 2026: 15 · 2025: 18 · 2024: 26 · 2023: 10 · 2022: 23 · 2021: 32 · 2020: 18 · 2019: 16 · 2018: 21 · 2017: 15 · 2016: 7 · 2015: 4
- FWCI
- 15.77
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- American Journal of Neuroradiology (publishedVersion, cc-by)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Keywords
- benign thyroid nodules, nodular goiter, radiofrequency ablation, thyroidectomy, surgical resection, hypothyroidism, postoperative complications, cost-effectiveness, length of hospital stay, thyrotoxicosis
- MeSH terms
- Adult, Aged, Female, Goiter, Humans, Male, Middle Aged, Postoperative Period, Thyroidectomy, Thyroid Nodule, Treatment Outcome, Catheter Ablation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
