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Epidemiology of Extrapulmonary Tuberculosis among Inpatients, China, 2008–2017

Open access
Pang, Yu, An, Jun, Shu, Wei, Huo, Fengmin, Chu, Naihui, Gao, Mengqiu, Qin, Shibing, Huang, Hairong, Chen, Xiaoyou, Xu, Shaofa·2019·Emerging Infectious Diseases

Abstract

We investigated the epidemiology of extrapulmonary tuberculosis (TB) among patients admitted to Beijing Chest Hospital, Beijing, China, during January 2008-December 2017. Of 19,279 hospitalized TB patients, 33.4% (6,433) had extrapulmonary TB and 66.6% (12,846) had pulmonary TB. The most frequent forms of extrapulmonary TB observed were skeletal TB (41.1%) and pleural TB (26.0%). Younger, female patients from rural areas were more likely to have extrapulmonary TB. However, patients with diabetes mellitus were less likely to have extrapulmonary TB compared with patients without diabetes. A higher proportion of multidrug-resistant (MDR) TB was observed among patients with extrapulmonary TB than among patients with pulmonary TB. We observed a large increase in MDR TB, from 17.3% to 35.7%, for pleural TB cases. The increasing rate of drug resistance among extrapulmonary TB cases highlights the need for drug susceptibility testing and the formulation of more effective regimens for extrapulmonary TB treatment.

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Research works printed but not linked: 25

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Cited by

Metadata

Authors
Pang, Y., An, J., Shu, W., Huo, F., Chu, N., Gao, M., Qin, S., Huang, H., Chen, X., & Xu, S.
Venue
Emerging Infectious Diseases
Published
2019-03
Volume
25
Issue
3
Pages
457-464
ISSN
  • 1080-6040 (ISSN-L)
  • 1080-6059
OpenAlex
W2912301188
Cited by
282
References
5
FWCI
24.54
Type
journal article
Language
en
Open access
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