The DOI matches its Crossref record; 192 of the 192 references it cites were found in a registry or an index.
The Relationship between Obstructive Sleep Apnea and Alzheimer’s Disease
Open accessAbstract
Obstructive sleep apnea (OSA) and Alzheimer's disease (AD) are highly prevalent conditions with growing impact on our aging society. While the causes of OSA are now better characterized, the mechanisms underlying AD are still largely unknown, challenging the development of effective treatments. Cognitive impairment, especially affecting attention and executive functions, is a recognized clinical consequence of OSA. A deeper contribution of OSA to AD pathogenesis is now gaining support from several lines of research. OSA is intrinsically associated with disruptions of sleep architecture, intermittent hypoxia and oxidative stress, intrathoracic and hemodynamic changes as well as cardiovascular comorbidities. All of these could increase the risk for AD, rendering OSA as a potential modifiable target for AD prevention. Evidence supporting the relevance of each of these mechanisms for AD risk, as well as a possible effect of AD in OSA expression, will be explored in this review.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Poor sleep quality such as that caused by obstructive sleep apnea may increase risk by interfering with blood flow to the brain and normal patterns of brain activity that promote memory and attention.198,199”
From 2023 Alzheimer's disease facts and figures (2023) · cites this paper as [198]
The cited source says what the claim attributes to it.
In the citing paper
“In addition, poor sleep quality such as that caused by obstructive sleep apnea may increase risk by interfering with blood flow to the brain and normal patterns of brain activity that promote memory and attention.”
From 2024 Alzheimer's disease facts and figures (2024) · cites this paper as [212]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Amyloid oligomers exacerbate tau pathology in a mouse model of tauopathy
Selenica, M.-L. B., Brownlow, M., Jimenez, J. P., Lee, D. C., Pena, G., Dickey, C. A., Gordon, M. N., & Morgan, D. (2013) · Neurodegenerative Diseases · doi:10.1159/000337230 · Cited by 10,359
The Occurrence of Sleep-Disordered Breathing among Middle-Aged Adults
Young, T., Palta, M., Dempsey, J., Skatrud, J., Weber, S., & Badr, S. (1993) · New England Journal of Medicine · doi:10.1056/nejm199304293281704 · Cited by 10,183
Sleep Drives Metabolite Clearance from the Adult Brain
Xie, L., Kang, H., Xu, Q., Chen, M. J., Liao, Y., Thiyagarajan, M., O’Donnell, J., Christensen, D. J., Nicholson, C., Iliff, J. J., et al. (2013) · Science · doi:10.1126/science.1241224 · Cited by 5,411
Berry, R. B., Budhiraja, R., Gottlieb, D. J., Gozal, D., Iber, C., Kapur, V. K., Marcus, C. L., Mehra, R., Parthasarathy, S., Quan, S. F., et al. (2012) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.2172 · Cited by 5,302
Prospective Study of the Association between Sleep-Disordered Breathing and Hypertension
Peppard, P. E., Young, T., Palta, M., & Skatrud, J. (2000) · New England Journal of Medicine · doi:10.1056/nejm200005113421901 · Cited by 4,973
Marin, J. M., Carrizo, S. J., Vicente, E., & Agusti, A. G. (2005) · The Lancet · doi:10.1016/s0140-6736(05)71141-7 · Cited by 4,678
Hearing loss and cognitive decline in older adults
Lin, F. R., Yaffe, K., Xia, J., Xue, Q.-L., Harris, T. B., Purchase-Helzner, E., Satterfield, S., Ayonayon, H. N., Ferrucci, L., Simonsick, E. M., et al. (2013) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.1868 · Cited by 4,017
Diekelmann, S., & Born, J. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2762 · Cited by 3,760
The Triad of Sleep Apnea, Hypertension, and Chronic Kidney Disease: A Spectrum of Common Pathology
Aziz, F., & Chaudhary, K. R. (2016) · Cardiorenal Medicine · doi:10.1159/000450796 · Cited by 3,285
Sympathetic neural mechanisms in obstructive sleep apnea.
Somers, V. K., Dyken, M. E., Clary, M. P., & Abboud, F. M. (1995) · Journal of Clinical Investigation · doi:10.1172/jci118235 · Cited by 2,527
Research works printed but not linked: 1
- Somers, 2008, Circulation, 1080
Cited by
Sorted by citations
2023 Alzheimer's disease facts and figures
(2023) · Alzheimer's & Dementia · doi:10.1002/alz.13016 · Cited by 3,212
2024 Alzheimer's disease facts and figures
(2024) · Alzheimer's & Dementia · doi:10.1002/alz.13809 · Cited by 2,536
Revisiting the neurovascular unit
Schaeffer, S. M., & Iadecola, C. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00904-7 · Cited by 699
2025 Alzheimer's disease facts and figures
(2025) · Alzheimer s & Dementia · doi:10.1002/alz.70235 · Cited by 642
International Consensus Statement on Obstructive Sleep Apnea
Chang, J. L., Goldberg, A. N., Alt, J. A., Mohammed, A., Ashbrook, L., Auckley, D., Ayappa, I., Bakhtiar, H., Barrera, J. E., Bartley, B. L., et al. (2023) · International Forum of Allergy & Rhinology · doi:10.1002/alr.23079 · Cited by 350
Hypoxia and brain aging: Neurodegeneration or neuroprotection?
Burtscher, J., Mallet, R. T., Burtscher, M., & Millet, G. P. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101343 · Cited by 359
Promoting Successful Cognitive Aging: A Ten-Year Update
Krivanek, T. J., Gale, S. A., McFeeley, B. M., Nicastri, C. M., & Daffner, K. R. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201462 · Cited by 188
Sleep-disordered breathing and the risk of Alzheimer's disease
Liguori, C., Maestri, M., Spanetta, M., Placidi, F., Bonanni, E., Mercuri, N. B., & Guarnieri, B. (2020) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2020.101375 · Cited by 154
Molecular Pathology, Oxidative Stress, and Biomarkers in Obstructive Sleep Apnea
Meliante, P. G., Zoccali, F., Cascone, F., Stefano, V. D., Greco, A., VINCENTIIS, M. D., Petrella, C., Fiore, M., Minni, A., & Barbato, C. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24065478 · Cited by 128
Lal, C., Ayappa, I. A., Ayas, N., Beaudin, A. E., Hoyos, C. M., Kushida, C. A., Kamińska, M., Mullins, A. E., Naismith, S. L., Osorio, R. S., et al. (2022) · Annals of the American Thoracic Society · doi:10.1513/annalsats.202205-380st · Cited by 114
Self-citationThe interplay of hypoxic and mental stress: Implications for anxiety and depressive disorders
Burtscher, J., Niedermeier, M., Hüfner, K., van den Burg, E. H., Kopp, M., Stoop, R., Burtscher, M., Gatterer, H., & Millet, G. P. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104718 · Cited by 110
Wang, F., Zou, J., Xu, H., Huang, W., Zhang, X., Wei, Z., Li, X., Liu, Y., Zou, J., Liu, F., et al. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.820939 · Cited by 75
Tsai, M., Li, H., Huang, C., Wang, R., Chuang, L., Chen, N., Liu, C., Yang, Y., Liu, C., Hsu, C., et al. (2020) · The Laryngoscope · doi:10.1002/lary.28558 · Cited by 62
Sleep–wake regulation and the hallmarks of the pathogenesis of Alzheimer’s disease
Egroo, M. V., Narbutas, J., Chylinski, D., González, P. V., Maquet, P., Salmon, É., Bastin, C., Collette, F., & Vandewalle, G. (2019) · SLEEP · doi:10.1093/sleep/zsz017 · Cited by 66
Siddappaji, K. K., & Gopal, S. (2021) · AIMS neuroscience · doi:10.3934/neuroscience.2021020 · Cited by 58
Appleton, S., Vakulin, A., D'Rozario, A. L., Vincent, A. D., Teare, A. J., Martin, S., Wittert, G., McEvoy, R. D., CATCHESIDE, P. G., & Adams, R. (2019) · SLEEP · doi:10.1093/sleep/zsz092 · Cited by 49
Obstructive Sleep Apnea, Circadian Clock Disruption, and Metabolic Consequences
Malicki, M., Karuga, F. F., Szmyd, B. M., Sochal, M., & Gabryelska, A. (2022) · Metabolites · doi:10.3390/metabo13010060 · Cited by 50
Kang, J., Tian, Z., Wei, J., Mu, Z., Liang, J., & Li, M. (2022) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2022.06.004 · Cited by 47
Patel, A. A., & Chong, D. J. (2021) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2021.04.007 · Cited by 45
Baumer, N., Becker, M. L., Capone, G. T., Egan, K. M., Fortea, J., Handen, B. L., Head, E., Hendrix, J. E., Litovsky, R. Y., Strydom, A., et al. (2022) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-022-09435-z · Cited by 42
Sircu, V., Colesnic, S., Covanţev, S., Corlateanu, O., Sukhotko, A. S., Popovici, C., & Corlăteanu, A. (2023) · Clocks & Sleep · doi:10.3390/clockssleep5020025 · Cited by 44
2026 Alzheimer's disease facts and figures
(2026) · Alzheimer s & Dementia · doi:10.1002/alz.71345 · Cited by 67
Choi, J. W., Kim, D. H., Koo, D. L., Park, Y., Nam, H., Lee, J.-H., Kim, H. J., Hong, S., Jang, G. S., Lim, S., et al. (2022) · Sensors · doi:10.3390/s22197177 · Cited by 40
Sani, T. P., Bond, R. L., Marshall, C. R., Hardy, C. J. D., Russell, L. L., Moore, K. M., Slattery, C. F., Paterson, R. W., Woollacott, I., Wendi, I. P., et al. (2019) · eNeurologicalSci · doi:10.1016/j.ensci.2019.100212 · Cited by 38
Intricate relationship between obstructive sleep apnea and dementia in older adults
Ercolano, E., Bencivenga, L., Palaia, M. E., Carbone, G., Scognamiglio, F., Rengo, G., & Femminella, G. D. (2023) · GeroScience · doi:10.1007/s11357-023-00958-4 · Cited by 41
Li, J., Zhao, L., Ding, X., Cui, X., Li, Q., & Chen, Y. (2022) · Sleep Medicine · doi:10.1016/j.sleep.2022.06.004 · Cited by 40
Carpi, M., Fernandes, M., Mercuri, N. B., & Liguori, C. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-230933 · Cited by 41
Jiang, X. G., Wang, Z., Hu, N., Yang, Y., Xiong, R., & Fu, Z. (2021) · Experimental Brain Research · doi:10.1007/s00221-021-06225-2 · Cited by 37
The Role of Inflammation in Cognitive Impairment of Obstructive Sleep Apnea Syndrome
Yang, C., Zhou, Y., Liu, H., & Xu, P. (2022) · Brain Sciences · doi:10.3390/brainsci12101303 · Cited by 37
Bransby, L., Rosenich, E., Maruff, P. T., & Lim, Y. Y. (2023) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2023.119 · Cited by 37
Obstructive Sleep Apnea, Hypercoagulability, and the Blood–Brain Barrier
Zolotoff, C., Bertoletti, L., Gozal, D., Mismetti, V., Flandrin‐Gresta, P., Roche, F., & Perek, N. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10143099 · Cited by 35
Carroll, C. M., & Macauley, S. L. (2019) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2019.00258 · Cited by 32
Fernandes, M., Mari, L., Chiaravalloti, A., Paoli, B., Nuccetelli, M., Izzi, F., Giambrone, M. P., Camedda, R., Bernardini, S., Schillaci, O., et al. (2022) · Journal of Neurology · doi:10.1007/s00415-022-11182-z · Cited by 32
Li, W., Yang, S., Yu, F., Zhao, Y., Sun, Z., An, J., & Ji, E. (2018) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2018.09.012 · Cited by 32
Wang, H., Yang, T., Sun, J., Zhang, S., & Liu, S. (2021) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.16689 · Cited by 31
Current and future strategies for diagnostic and management of obstructive sleep apnea
Khurana, S., Soda, N., Shiddiky, M. J. A., Nayak, R., & Bose, S. K. (2021) · Expert Review of Molecular Diagnostics · doi:10.1080/14737159.2021.2002686 · Cited by 32
Kong, W., Zheng, Y., Xu, W., Gu, H., & Wu, J. (2020) · European Archives of Oto-Rhino-Laryngology · doi:10.1007/s00405-020-05948-2 · Cited by 31
Zhao, L., Liu, T., Dou, Z., Wang, M., Hu, Z., & Wang, B. (2021) · BMC Nephrology · doi:10.1186/s12882-021-02362-6 · Cited by 31
Sleep electroencephalography biomarkers of cognition in obstructive sleep apnea
Gu, Y., Gagnon, J., & Kamińska, M. (2023) · Journal of Sleep Research · doi:10.1111/jsr.13831 · Cited by 29
Aini, N., Chu, H., Banda, K. J., Chen, R., Lee, T., Pien, L., Liu, D., Lai, Y.-J., Kang, X. L., & Chou, K. (2023) · Sleep Medicine · doi:10.1016/j.sleep.2023.01.020 · Cited by 30
Lui, K. K., Dave, A., Sprecher, K. E., Chappel-Farley, M. G., Riedner, B. A., Heston, M. B., Taylor, C. E., Carlsson, C. M., Okonkwo, O. C., Asthana, S., et al. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01446-3 · Cited by 30
Potential Roles of Hypoxia-Inducible Factor-1 in Alzheimer’s Disease: Beneficial or Detrimental?
Lin, T., Huang, C.-R., Lin, K.-J., Hsieh, Y.-H., Chen, S., Lin, Y., Chao, A., & Yang, D. (2024) · Antioxidants · doi:10.3390/antiox13111378 · Cited by 30
Sex and Sleep Disruption as Contributing Factors in Alzheimer’s Disease
Johnson, C. E., Duncan, M. J., & Murphy, M. P. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-230527 · Cited by 34
Obstructive sleep apnoea and cognitive decline in mild-to-moderate Alzheimer's disease
Jorge, C., Targa, A., Benitez, I. D., Dakterzada, F., Torres, G., Mínguez, O., Carnes, A., Pujol, M., Gibert, A., Ortega, R. L., et al. (2020) · European Respiratory Journal · doi:10.1183/13993003.00523-2020 · Cited by 27
The Bidirectional Relationship Between Obstructive Sleep Apnea and Chronic Kidney Disease
Hui, L., & Benca, R. M. (2021) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2021.105652 · Cited by 27
Predicting Alzheimer's disease CSF core biomarkers: a multimodal Machine Learning approach
Gaeta, A. M., Quijada-López, M., Barbé, F., Vaca, R., Pujol, M., Mínguez, O., Sánchez‐de‐la‐Torre, M., Muñoz‐Barrutia, A., & Piñol‐Ripoll, G. (2024) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2024.1369545 · Cited by 30
The role of reactive oxygen species in cognitive impairment associated with sleep apnea
Xu, L., Yang, Y., & Chen, J. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.9132 · Cited by 27
Severe Obstructive Sleep Apnea and Increased Cortical Amyloid-β Deposition
Ylä-Herttuala, S., Hakulinen, M. A., Poutiainen, P., Laitinen, T. M., Koivisto, A. M., Remes, A. M., Hallikainen, M., Lehtola, J.-M., Saari, T. T., Korhonen, V. E., et al. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200736 · Cited by 26
Sleep disorders in Alzheimer’s disease: the predictive roles and potential mechanisms
Kuang, H., Zhu, Y., Zhou, Z., Yang, M.-W., Hong, F.-F., & Yang, M.-W. (2021) · Neural Regeneration Research · doi:10.4103/1673-5374.308071 · Cited by 27
Li, H., Li, L., Kong, L., Li, P., Zeng, Y., Li, K., Xie, W., Shu, Y., Liu, X., & Peng, D. (2021) · Nature and Science of Sleep · doi:10.2147/nss.s344842 · Cited by 26
Wrzesień, A., Andrzejewski, K., Jampolska, M., & Kaczyńska, K. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25042327 · Cited by 25
Obstructive sleep apnea in adults with Down syndrome
Landete, P., Soriano, J. B., Orzaiz, B. A., Zamora, E., Acosta, C., Erro, M., Riolobos, C. L., Ramos, M. I., Moldenhauer, F., & Ancochea, J. (2020) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.61853 · Cited by 25
Yang, X., Geng, L., Li, R., Song, J., Jia, C.-L., An, J., Sun, M.-F., Xu, S., Guo, Y., Zhao, Y., et al. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s393346 · Cited by 25
Wang, H., Wang, X., Shen, Y., Wang, Y., Yang, T., Sun, J., & Liu, S. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.110230 · Cited by 25
Critical thinking on amyloid-beta-targeted therapy: challenges and perspectives
Sun, B., Chen, Y., Fan, D., Zhu, C., Zeng, F., & Wang, Y. (2020) · Science China Life Sciences · doi:10.1007/s11427-020-1810-y · Cited by 27
Gut microbiota dysbiosis in 4‐ to 6‐year‐old children with obstructive sleep apnea–hypopnea syndrome
Wu, J., Lu, Y., Cai, X., Chen, Y., Shen, Z., & Lyv, Q. (2022) · Pediatric Pulmonology · doi:10.1002/ppul.25967 · Cited by 26
Ni, W., Niu, Y., Cao, S., Fan, C., Fan, J., Zhu, L., & Wang, X. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03160-1 · Cited by 24
Hypoxic–hyperoxic conditioning and dementia
Mallet, R. T., Burtscher, J., Manukhina, E. B., Downey, H. F., Glazachev, O. S., Serebrovskaya, T. V., & Burtscher, M. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-815854-8.00047-1 · Cited by 23
Aberrant waste disposal in neurodegeneration: why improved sleep could be the solution
Wafford, K. A. (2021) · Cerebral Circulation - Cognition and Behavior · doi:10.1016/j.cccb.2021.100025 · Cited by 25
Nabavi, S. K., & Bhadra, S. (2021) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2021.3065824 · Cited by 21
Involvement of Hepcidin in Cognitive Damage Induced by Chronic Intermittent Hypoxia in Mice
Zhao, Y., Tan, M., Song, J., An, J., Yang, X., Li, W., Guo, Y., & Ji, E. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/8520967 · Cited by 21
Fernandes, M., Chiaravalloti, A., Manfredi, N., Placidi, F., Nuccetelli, M., Izzi, F., Camedda, R., Bernardini, S., Schillaci, O., Mercuri, N. B., et al. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-215734 · Cited by 21
Obstructive Sleep Apnea and Striatal Dopamine Availability in Parkinson's Disease
Oh, Y., Kim, J., Lyoo, C. H., & Kim, H. (2023) · Movement Disorders · doi:10.1002/mds.29402 · Cited by 22
A wireless, real-time respiratory effort and body position monitoring system for sleep
Hernandez, J. E., & Cretu, E. (2020) · Biomedical Signal Processing and Control · doi:10.1016/j.bspc.2020.102023 · Cited by 21
Hypoperfusion is a potential inducer of immunosuppressive network in Alzheimer's disease
Salminen, A. (2020) · Neurochemistry International · doi:10.1016/j.neuint.2020.104919 · Cited by 20
The Association of Periodontitis and Alzheimer’s Disease: How to Hit Two Birds with One Stone
Werber, T., Bata, Z., Vaszine, E. S., Berente, D. B., Kamondi, A., & Horvath, A. A. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210491 · Cited by 23
Gabryelska, A., Turkiewicz, S., Ditmer, M., & Sochal, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24031808 · Cited by 21
Choe, Y. M., Suh, G., Kim, J. W., & Initiative, A. D. N. (2022) · Psychiatry Investigation · doi:10.30773/pi.2022.0176 · Cited by 19
Li, C., & Shi, S. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1224396 · Cited by 19
Cai, S., Li, S., Zhou, Y., Song, J., & Peng, J. (2024) · BMC Oral Health · doi:10.1186/s12903-024-03960-0 · Cited by 20
Hypoxia/ischemia impairs CD33 (Siglec-3)/TREM2 signaling: Potential role in Alzheimer's pathogenesis
Salminen, A., Kaarniranta, K., & Kauppinen, A. (2021) · Neurochemistry International · doi:10.1016/j.neuint.2021.105186 · Cited by 20
Role of angiotensin II in chronic intermittent hypoxia-induced hypertension and cognitive decline
Marciante, A. B., Shell, B., Farmer, G. E., & Cunningham, J. T. (2021) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00222.2020 · Cited by 18
Chen, D., Wang, X., Huang, T., & Huang, T. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.794202 · Cited by 20
Exploring the nexus: Sleep disorders, circadian dysregulation, and Alzheimer’s disease
Khandayataray, P., & Murthy, M. K. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.03.066 · Cited by 19
Yoon, S. H., Kim, H., Lee, J., Chun, J., Sohn, Y. H., Lee, P. H., Ryu, Y. H., Cho, H., Yoo, H. S., & Lyoo, C. H. (2023) · Neurology · doi:10.1212/wnl.0000000000207917 · Cited by 18
Simple and Unbiased OSA Prescreening: Introduction of a New Morphologic OSA Prediction Score
Laharnar, N., Herberger, S., Prochnow, L., Chen, N., Cistulli, P. A., Pack, A. I., Schwab, R. J., Keenan, B. T., Mazzotti, D. R., Fietze, I., et al. (2021) · Nature and Science of Sleep · doi:10.2147/nss.s333471 · Cited by 16
Intermittent hypoxia treatments cause cellular priming in human microglia
Felice, M. D., Germelli, L., Piccarducci, R., Pozzo, E. D., Giacomelli, C., Baccaglini‐Frank, A., & Martini, C. (2023) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.17682 · Cited by 16
The Park Sleep subtype in Parkinson’s disease: from concept to clinic
Tall, P., Qamar, M. A., Rosenzweig, I., Raeder, V., Sauerbier, A., Zach, H., Falup‐Pecurariu, C., & Chaudhuri, К. R. (2023) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2023.2242786 · Cited by 17
Chen, Q., Lin, G., Huang, J., Chen, L., Liu, Y., Huang, J., Zhang, S., & Lin, Q. (2020) · Aging · doi:10.18632/aging.102729 · Cited by 16
Parker, J. L., Appleton, S., Melaku, Y. A., D'Rozario, A. L., Wittert, G., Martin, S., Toson, B., CATCHESIDE, P. G., Lechat, B., Teare, A. J., et al. (2022) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.9934 · Cited by 16
Alzheimer's Disease Detection in EEG Sleep Signals
Gallego-Viñarás, L., Mira‐Tomas, J. M., Gaeta, A. M., Piñol‐Ripoll, G., Barbé, F., Olmos, P. M., & Muñoz‐Barrutia, A. (2024) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2024.3478380 · Cited by 15
Wing, D., Eyler, L. T., Lenze, E. J., Wetherell, J. L., Nichols, J. F., MEEUSEN, R. R., Godino, J., Shimony, J. S., Snyder, A. Z., Nishino, T., et al. (2022) · Neuroimage Reports · doi:10.1016/j.ynirp.2022.100146 · Cited by 16
Sarcopenia of the longitudinal tongue muscles in rats
Sieck, G. C., Hernandez-Vizcarrondo, G. A., Brown, A. D., & Fogarty, M. J. (2023) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2023.104180 · Cited by 15
Tang, S., Zhu, J., Zhao, D., Mo, H., Zeng, Z., Xiong, M., Dong, M., & Hu, K. (2020) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2020.08.027 · Cited by 13
Dose-dependent phosphorylation of endogenous Tau by intermittent hypoxia in rat brain
Marciante, A. B., Howard, J. C., Kelly, M. N., Santiago‐Moreno, J., Allen, L. L., Gonzalez‐Rothi, E. J., & Mitchell, G. S. (2022) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00332.2022 · Cited by 15
Impact of Pharmacotherapy on Insomnia in Patients with Alzheimer’s Disease
Roland, J. P., & Bliwise, D. L. (2021) · Drugs & Aging · doi:10.1007/s40266-021-00891-1 · Cited by 14
Muzambi, R., Bhaskaran, K., Rentsch, C. T., Smeeth, L. L., Brayne, C., Garfield, V., Williams, D. M., Chaturvedi, N., & Warren‐Gash, C. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-02145-z · Cited by 15
Toljan, K., & Homolak, J. (2021) · Handbook of clinical neurology · doi:10.1016/b978-0-12-819975-6.00018-2 · Cited by 15
Shahbazi, M., Heidari, R., Tafakhori, A., Samadi, S., Nikeghbalian, Z., Amirifard, H., & Najafi, A. (2023) · Sleep Medicine · doi:10.1016/j.sleep.2023.11.006 · Cited by 13
Wondie, A., Taderegew, M. M., Girma, B., Getawey, A., Tsega, D., Terefe, T. F., Mitiku, S., & Berhanu, H. (2022) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-022-00931-9 · Cited by 18
Tsou, Y., Hsu, C.-C., Shih, L., Lin, T.-C., Chiu, C., Tien, V. H.-C., Tsai, M., & Chang, W. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10143169 · Cited by 13
Chien, W.-C., Lin, C., Liu, C., Chen, S., Chou, M., & Hsu, C. (2023) · Biomedicines · doi:10.3390/biomedicines11020621 · Cited by 12
Tian, Y., Wang, S., Tong, W., Wang, H., Zhang, Y., & Teng, B. (2023) · International Immunopharmacology · doi:10.1016/j.intimp.2023.111234 · Cited by 12
Huang, Y.-P., Chien, W., Chung, C., Huang, Y., Kuo, S.-C., Chen, C., Chen, T., Chang, H., Kao, Y., Chang, S., et al. (2022) · Sleep Medicine · doi:10.1016/j.sleep.2022.10.031 · Cited by 12
Decoding Causal Links Between Sleep Apnea and Alzheimer’s Disease
Ferini‐Strambi, L., Hensley, M., & Salsone, M. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201066 · Cited by 12
Huang, Z. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-221042 · Cited by 12
BACE1 as an early biomarker and its relevance to risk factors for Alzheimer’s disease
Ohno, M. (2025) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2025.111475 · Cited by 12
García-García, C., Moreno, L., Alacreu, M., Muñoz–Almaraz, F. J., & Martínez, L. A. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph191912911 · Cited by 12
DeVettori, G., Troxel, W., Duff, K. M., & Baron, K. G. (2023) · Sleep Medicine · doi:10.1016/j.sleep.2023.08.029 · Cited by 11
Exploring the combined effects of sleep apnea and APOE-e4 on biomarkers of Alzheimer’s disease
Turner, A. D., Locklear, C. E., Oruru, D., Briggs, A., Bubu, O. M., & Seixas, A. A. (2023) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.1017521 · Cited by 9
Self-citation
Metadata
- Authors
- Andrade, A. G., Bubu, O. M., Varga, A. W., & Osorio, R. S.
- Affiliations
- NYU Langone Health (US)
- University of South Florida (US)
- Icahn School of Medicine at Mount Sinai (US)
- Nathan Kline Institute for Psychiatric Research (US)
- Corresponding author
- Andrade, Andreia G.
- Osorio, Ricardo S.
- Venue
- Journal of Alzheimer's Disease
- Publisher
- SAGE Publications
- Published
- 2018-06-12
- Volume
- 64
- Issue
- s1
- Pages
- S255-S270
- ISSN
- 1387-2877 (ISSN-L)
- 1875-8908
- PMC
- PMC6542637
- OpenAlex
- W2804158148
- Cited by
- 216
- References
- 191
- Citations by year
- 2026: 18 · 2025: 29 · 2024: 38 · 2023: 43 · 2022: 32 · 2021: 29 · 2020: 19 · 2019: 5 · 2018: 1
- FWCI
- 1.77
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Alzheimer s Disease (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Digital Commons - University of South Florida (University of South Florida) (submittedVersion)
- Funders
- National Institute on Aging (R01AG056682, R01AG022374, R21AG055002, R21AG049348, P30AG008051, R01AG056031, R21AG059179)
- National Heart, Lung, and Blood Institute (R01HL118624)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Alzheimer's disease research and treatments
- Keywords
- obstructive sleep apnea, Alzheimer's disease
- MeSH terms
- Alzheimer Disease, Animals, Humans, Sleep Apnea, Obstructive
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
