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Lymphedema: A primer on the identification and management of a chronic condition in oncologic treatment
Open accessAbstract
The primary goals of oncologic therapy are the compassionate care of cancer patients, eradication of disease, and palliation of symptoms. Advances in various targeted therapies such as highly conformal and image-guided radiotherapy techniques, sentinel lymph node dissection, and molecularly targeted agents hold the promise of allowing those goals to be reached with fewer treatment-related complications. Unfortunately, certain side effects remain problematic due to the inability to completely avoid injuring normal tissues. Lymphedema, a chronic condition that occurs as a result of the body's inability to drain lymph fluid from the tissues, is a common treatment-related side effect experienced by cancer patients. In this review, many of the important aspects of lymphedema with which clinicians who treat cancer patients should be familiar are outlined, including the anatomy, pathophysiology, diagnosis, and management of this condition. The authors also identify some of the resources available both to cancer patients with lymphedema and to the clinicians who treat them. It is hoped that this review will convey the importance of the early identification and management of this incurable disorder because this is essential to minimizing its complications.
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Cites
Lucci, A., McCall, L. M., Beitsch, P. D., Whitworth, P. W., Reintgen, D. S., Blumencranz, P. W., Leitch, A. M., Saha, S., Hunt, K. K., & Giuliano, A. E. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2006.07.4062 · Cited by 920
Risk of lymphoedema following the treatment of breast cancer
Kissin, M. W., Della Rovere, G. Q., Easton, D., & Westbury, G. (1986) · Journal of British Surgery · doi:10.1002/bjs.1800730723 · Cited by 716
Wilke, L. G., McCall, L. M., Posther, K. E., Whitworth, P. W., Reintgen, D. S., Leitch, A. M., Gabram, S. G. A., Lucci, A., Cox, C. E., Hunt, K. K., et al. (2006) · Annals of Surgical Oncology · doi:10.1245/aso.2006.05.013 · Cited by 580
Arm edema in breast cancer patients
Erickson, V. S., Pearson, M. L., Ganz, P. A., Adams, J., & Kahn, K. L. (2001) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/93.2.96 · Cited by 560
Fleissig, A., Fallowfield, L. J., Langridge, C. I., Johnson, L., Newcombe, R. G., Dixon, J. M., Kissin, M., & Mansel, R. E. (2006) · Breast Cancer Research and Treatment · doi:10.1007/s10549-005-9025-7 · Cited by 494
A Comparison of Four Diagnostic Criteria for Lymphedema in a Post-Breast Cancer Population
Armer, J. M., & Stewart, B. R. (2005) · Lymphatic Research and Biology · doi:10.1089/lrb.2005.3.208 · Cited by 359
Effective Treatment of Lymphedema of the Extremities
Ko, D. S. C. (1998) · Archives of Surgery · doi:10.1001/archsurg.133.4.452 · Cited by 354
Langer, I., Guller, U., Berclaz, G., Koechli, O. R., Schaer, G., Fehr, M. K., Hess, T., Oertli, D., Bronz, L., Schnarwyler, B., et al. (2007) · Annals of Surgery · doi:10.1097/01.sla.0000245472.47748.ec · Cited by 353
Randomized Controlled Trial of Weight Training and Lymphedema in Breast Cancer Survivors
Ahmed, R. L., Thomas, W., Yee, D., & Schmitz, K. H. (2006) · Journal of Clinical Oncology · doi:10.1200/jco.2005.03.6749 · Cited by 332
Lymphedema and Quality of Life in Survivors of Early-Stage Breast Cancer
Beaulac, S. M. (2002) · Archives of Surgery · doi:10.1001/archsurg.137.11.1253 · Cited by 308
Predicting Breast Cancer-Related Lymphedema Using Self-Reported Symptoms
Armer, J. M., Radina, M. E., Porock, D., & Culbertson, S. D. (2003) · Nursing Research · doi:10.1097/00006199-200311000-00004 · Cited by 305
Quality of life and a symptom cluster associated with breast cancer treatment-related lymphedema
Ridner, S. H. (2005) · Supportive Care in Cancer · doi:10.1007/s00520-005-0810-y · Cited by 305
McNeely, M. L., Magee, D. J., Lees, A. W., Bagnall, K. M., Haykowsky, M., & Hanson, J. (2004) · Breast Cancer Research and Treatment · doi:10.1023/b:brea.0000032978.67677.9f · Cited by 285
Andersen, L., Højris, I., Erlandsen, M., & Andersen, J. (2000) · Acta Oncologica · doi:10.1080/028418600750013186 · Cited by 262
Psychologic and social sequelae of secondary lymphedema: A review
McWayne, J., & Heiney, S. P. (2005) · Cancer · doi:10.1002/cncr.21195 · Cited by 230
Deltombe, T., Jamart, J., Recloux, S., Legrand, C., Vandenbroeck, N., Theys, S., & Hanson, P. (2007) · PubMed · Cited by 221
Risk of lymphedema after regional nodal irradiation with breast conservation therapy
Powell, S. N., Taghian, A. G., Kachnic, L. A., Coen, J. J., & Assaad, S. I. (2003) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(02)04273-6 · Cited by 215
Damstra, R. J., Voesten, H. G. J., van Schelven, W. D., & van der Lei, B. (2009) · Breast Cancer Research and Treatment · doi:10.1007/s10549-008-9932-5 · Cited by 192
Brorson, H., Ohlin, K., Olsson, G., & Nilsson, M. (2006) · Lymphatic Research and Biology · doi:10.1089/lrb.2006.4404 · Cited by 190
Physical therapies for reducing and controlling lymphoedema of the limbs
Preston, N. J., Seers, K., & Mortimer, P. S. (2004) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003141.pub2 · Cited by 181
Lymphedema Management: The Comprehensive Guide for Practitioners
Zuther, J. E., & Norton, S. (2009) · Cited by 164
Lymphedema Secondary to Postmastectomy Radiation: Incidence and Risk Factors
Hinrichs, C. S., Watroba, N., Rezaishiraz, H., Giese, W. L., Hurd, T. C., Fassl, K. A., & Edge, S. B. (2004) · Annals of Surgical Oncology · doi:10.1245/aso.2004.04.017 · Cited by 156
Liljegren, G., & Holmberg, L. (1997) · European Journal of Cancer · doi:10.1016/s0959-8049(96)00375-9 · Cited by 156
F�ldi, E. (1998) · Cancer · doi:10.1002/(sici)1097-0142(19981215)83:12b+<2833::aid-cncr35>3.0.co;2-3 · Cited by 155
Breast radiotherapy and lymphedema
Meek, A. G. (1998) · Cancer · doi:10.1002/(sici)1097-0142(19981215)83:12b+<2788::aid-cncr27>3.0.co;2-i · Cited by 147
Johansson, K. I., Albertsson, M., Ingvar, C., & Ekdahl, C. S. (1999) · PubMed · Cited by 146
Golshan, M. A., Martin, W. J., & Dowlatshahi, K. (2003) · The American Surgeon · doi:10.1177/000313480306900306 · Cited by 143
Goffman, T. E., Laronga, C., Wilson, L., & Elkins, D. E. (2004) · The Breast Journal · doi:10.1111/j.1075-122x.2004.21411.x · Cited by 127
The Use of Bioimpedance Analysis to Evaluate Lymphedema
Warren, A. G., Janz, B. A., Slavin, S. A., & Borud, L. J. (2007) · Annals of Plastic Surgery · doi:10.1097/01.sap.0000244977.84130.cf · Cited by 120
Lymphedema : diagnosis and therapy
Weissleder, H., Schuchhardt, C., & Baumeister, R. G. H. (2008) · Medical Entomology and Zoology · Cited by 110
Lymphedema Therapy Reduces the Volume of Edema and Pain in Patients with Breast Cancer
Hamner, J. B., & Fleming, M. D. (2007) · Annals of Surgical Oncology · doi:10.1245/s10434-006-9332-1 · Cited by 110
Clarke, D. H., Martinez, A. A., Cox, R. S., & Goffinet, D. R. (1982) · Cancer · doi:10.1002/1097-0142(19820601)49:11<2295::aid-cncr2820491116>3.0.co;2-g · Cited by 105
Quality of life following liposuction and conservative treatment of arm lymphedema.
Brorson, H., Ohlin, K., Olsson, G., Långström, G., Wiklund, I. E., & Svensson, H. (2006) · PubMed · Cited by 104
Deutsch, M., Land, S. R., Begovič, M., & Sharif, S. (2007) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2007.07.2376 · Cited by 99
Breast lymphedema after breast conserving treatment
Rönkä, R., Pamilo, M., von Smitten, K. A. J., & Leidenius, M. (2004) · Acta Oncologica · doi:10.1080/02841860410014867 · Cited by 96
Lymphedema After Complete Axillary Node Dissection for Melanoma
Starritt, E. C., Joseph, D. M., McKinnon, J. G., Lo, S. K., de Wilt, J. H. W., & Thompson, J. F. (2004) · Annals of Surgery · doi:10.1097/01.sla.0000143271.32568.2b · Cited by 84
PREVALENCE AND AETIOLOGY OF LYMPHOEDEMA AFTER BREAST CANCER TREATMENT IN SOUTHERN TASMANIA
Edwards, T. L. (2000) · Australian and New Zealand Journal of Surgery · doi:10.1046/j.1440-1622.2000.01839.x · Cited by 77
Prospective trial of intensive decongestive physiotherapy for upper extremity lymphedema
Karadibak, D., Yavuzşen, T., & Saydam, S. (2008) · Journal of Surgical Oncology · doi:10.1002/jso.21035 · Cited by 77
Bates, D. O., Levick, J. R., & Mortimer, P. S. (1993) · Clinical Science · doi:10.1042/cs0850737 · Cited by 74
Bani, H., Fasching, P. A., Lux, M. P., Rauh, C., Willner, M., Eder, I., Loehberg, C. R., Schrauder, M. G., Beckmann, M. W., & Bani, M. R. (2007) · Patient Education and Counseling · doi:10.1016/j.pec.2007.01.004 · Cited by 74
LYMPHEDEMA 30 YEARS AFTER RADICAL MASTECTOMY
Brennan, M. J., & Weitz, J. (1992) · American Journal of Physical Medicine & Rehabilitation · doi:10.1097/00002060-199202000-00004 · Cited by 70
Prevention and management of arm lymphedema in the patient with breast cancer.
Golshan, M. A., & Smith, B. L. (2006) · PubMed · Cited by 69
Borup Christensen, S., & Lundgren, E. C. (1989) · PubMed · Cited by 51
ANATOMY OF THE LYMPHATIC SYSTEM
Kubik, S. (1939) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1939.tb116161.x · Cited by 51
Déry, M., Yonuschot, G., & Winterson, B. J. (2000) · PubMed · Cited by 42
Hinrichs, C. S., Gibbs, J. F., Driscoll, D., Kepner, J. L., Wilkinson, N. W., Edge, S. B., Fassl, K. A., Muir, R., & Kraybill, W. G. (2004) · Journal of Surgical Oncology · doi:10.1002/jso.20020 · Cited by 37
A Retrospective Review of Nodal Treatment for Vulvar Cancer
Petereit, D. G., Mehta, M. P., Buchler, D. A., et al. (1993) · American Journal of Clinical Oncology · doi:10.1097/00000421-199302000-00010 · Cited by 31
Secondary lymphedema in the cancer patient.
Lacovara, J. E., & Yoder, L. H. (2006) · PubMed · Cited by 12
Cited by
Cancer treatment and survivorship statistics, 2016
Miller, K. D., Siegel, R. L., Lin, C. C., Mariotto, A. B., Kramer, J. L., Rowland, J. H., Stein, K. D., Alteri, R., & Jemal, A. (2016) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21349 · Cited by 6,066
Cancer treatment and survivorship statistics, 2014
DeSantis, C. E., Lin, C. C., Mariotto, A. B., Siegel, R. L., Stein, K. D., Kramer, J. L., Alteri, R., Robbins, A. S., & Jemal, A. (2014) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21235 · Cited by 2,779
Psychosocial impact of lymphedema: a systematic review of literature from 2004 to 2011
Fu, M. R., Ridner, S. H., Hu, S. H., Stewart, B. R., Cormier, J. N., & Armer, J. M. (2013) · Psycho-Oncology · doi:10.1002/pon.3201 · Cited by 358
Manual lymphatic drainage for lymphedema following breast cancer treatment
Ezzo, J., Manheimer, E., McNeely, M. L., Howell, D. M., Weiss, R., Johansson, K. I., Bao, T., Bily, L., Tuppo, C. M., Williams, A. F., et al. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003475.pub2 · Cited by 323
Singh, B., Disipio, T., Peake, J., & Hayes, S. C. (2016) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2015.09.012 · Cited by 119
Metadata
- Authors
- Lawenda, B. D., Mondry, T. E., & Johnstone, P. A. S.
- Venue
- CA: A Cancer Journal for Clinicians
- Publisher
- Wiley
- Published
- 2009-01-01
- Volume
- 59
- Issue
- 1
- Pages
- 8-24
- ISSN
- 0007-9235 (ISSN-L)
- OpenAlex
- W2149157950
- Cited by
- 377
- References
- 48
- FWCI
- 8.35
- Type
- journal article
- Language
- en
- Open access
- gold
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