Cited by 47

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis

Vanhee, S., De Mulder, K., Van Caeneghem, Y., Verstichel, G., Van Roy, N., Menten, B., Velghe, I., Philippe, J. +6 more·2015·Haematologica

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Research works printed but not linked: 31

  1. Medvinsky A, Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell. 1996;86(6):897-906.
  2. Palis J, Robertson S, Kennedy M, Wall C, Keller G. Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development. 1999;126(22):5073-5084.
  3. Tober J, McGrath KE, Palis J. Primitive ery- thropoiesis and megakaryopoiesis in the yolk sac are independent of c-myb. Blood. 2008;111(5):2636-2639.
  4. Mucenski ML, McLain K, Kier AB, et al. A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell. 1991;65(4):677-689.
  5. Bertrand JY, Chi NC, Santoso B, Teng S, Stainier DY, Traver D. Haematopoietic stem cells derive directly from aortic endothelium during development. Nature. 2010;464(7285):108-111.
  6. Lieu YK, Reddy EP. Conditional c-myb knockout in adult hematopoietic stem cells leads to loss of self-renewal due to impaired proliferation and accelerated differentiation. Proc Natl Acad Sci USA. 2009;106(51): 21689-21694.
  7. Lieu YK, Reddy EP. Impaired adult myeloid progenitor CMP and GMP cell function in conditional c-myb-knockout mice. Cell Cycle. 2012;11(18):3504-3512.
  8. Schulz C, Gomez Perdiguero E, Chorro L, et al. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science. 2012;336(6077):86-90.
  9. Kyba M, Perlingeiro RC, Daley GQ. HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell. 2002;109(1):29-37.
  10. Ng ES, Davis RP, Azzola L, Stanley EG, Elefanty AG. Forced aggregation of defined numbers of human embryonic stem cells into embryoid bodies fosters robust, repro- ducible hematopoietic differentiation. Blood. 2005;106(5):1601-1603.
  11. Vodyanik MA, Thomson JA, Slukvin, II. Leukosialin (CD43) defines hematopoietic progenitors in human embryonic stem cell differentiation cultures. Blood. 2006; 108(6):2095-2105.
  12. Notta F, Doulatov S, Laurenti E, Poeppl A, Jurisica I, Dick JE. Isolation of single human hematopoietic stem cells capable of long- term multilineage engraftment. Science. 2011;333(6039):218-221.
  13. Qiu C, Olivier EN, Velho M, Bouhassira EE. Globin switches in yolk sac-like primitive and fetal-like definitive red blood cells pro- duced from human embryonic stem cells. Blood. 2008;111(4):2400-2408.
  14. Gaur M, Kamata T, Wang S, Moran B, Shattil SJ, Leavitt AD. Megakaryocytes derived from human embryonic stem cells: a genetically tractable system to study megakaryocytopoiesis and integrin function. J Thromb Haemost. 2006;4(2): 436-442.
  15. Choi KD, Vodyanik MA, Slukvin, II. Generation of mature human myelomono- cytic cells through expansion and differenti- ation of pluripotent stem cell-derived lin- CD34+CD43+CD45+ progenitors. J Clin Invest. 2009;119(9):2818-2829.
  16. Woll PS, Martin CH, Miller JS, Kaufman DS. Human embryonic stem cell-derived NK cells acquire functional receptors and cytolytic activity. J Immunol. 2005; 175(8):5095-5103.
  17. Timmermans F, Velghe I, Vanwalleghem L, et al. Generation of T cells from human embryonic stem cell-derived hematopoietic zones. J Immunol. 2009;182(11):6879-6888.
  18. Kennedy M, Awong G, Sturgeon CM, et al. T lymphocyte potential marks the emer- gence of definitive hematopoietic progeni- tors in human pluripotent stem cell differen- tiation cultures. Cell Rep. 2012; 2(6):1722- 1735.
  19. Yoshimoto M, Porayette P, Glosson NL, et al. Autonomous murine T-cell progenitor production in the extra-embryonic yolk sac before HSC emergence. Blood. 2012; 119(24):5706-5714.
  20. Ramond C, Berthault C, Burlen-Defranoux O, et al. Two waves of distinct hematopoi- etic progenitor cells colonize the fetal thy- mus. Nat Immunol. 2014;15(1):27-35.
  21. Ledran MH, Krassowska A, Armstrong L, et al. Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches. Cell Stem Cell. 2008;3(1):85-98.
  22. Wang L, Menendez P, Shojaei F, et al. Generation of hematopoietic repopulating cells from human embryonic stem cells inde- pendent of ectopic HOXB4 expression. J Exp Med. 2005;201(10):1603-1614.
  23. Amabile G, Welner RS, Nombela-Arrieta C, et al. In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells. Blood. 2013; 121(8):1255-1264.
  24. Doulatov S, Vo LT, Chou SS, et al. Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precur- sors. Cell Stem Cell. 2013;13(4):459-470.
  25. Rollini P, Kaiser S, Faes-van't Hull E, Kapp U, Leyvraz S. Long-term expansion of trans- plantable human fetal liver hematopoietic stem cells. Blood. 2004; 103(3):1166-1170.
  26. Huang J, Nguyen-McCarty M, Hexner EO, Danet-Desnoyers G, Klein PS. Maintenance of hematopoietic stem cells through regula- tion of Wnt and mTOR pathways. Nat Med. 2012;18(12):1778-1785.
  27. Conneally E, Cashman J, Petzer A, Eaves C. Expansion in vitro of transplantable human cord blood stem cells demonstrated using a quantitative assay of their lympho-myeloid repopulating activity in nonobese diabetic- scid/scid mice. Proc Natl Acad Sci USA. 1997;94(18):9836-9841.
  28. Sakamoto H, Dai G, Tsujino K, et al. Proper levels of c-Myb are discretely defined at dis- tinct steps of hematopoietic cell develop- ment. Blood. 2006;108(3):896-903.
  29. Clarke D, Vegiopoulos A, Crawford A, Mucenski M, Bonifer C, Frampton J. In vitro differentiation of c-myb(-/-) ES cells reveals that the colony forming capacity of unilineage macrophage precursors and myeloid progenitor commitment are c- Myb independent. Oncogene. 2000; 19(30):3343-3351.
  30. Ziegler-Heitbrock HW, Fingerle G, Strobel M, et al. The novel subset of CD14+/CD16+ blood monocytes exhibits features of tissue macrophages. Eur J Immunol. 1993;23(9): 2053-2058.
  31. Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat Rev Immunol. 2005;5(12):953-964.

Cited by

Sorted by citations

Authors
Vanhee, S., De Mulder, K., Van Caeneghem, Y., Verstichel, G., Van Roy, N., Menten, B., Velghe, I., Philippe, J., De Bleser, D., Lambrecht, B. N., Taghon, T., Leclercq, G., Kerre, T., & Vandekerckhove, B.
Venue
Haematologica
Published
2014-11-07
Volume
100
Issue
2
Pages
157-166
ISSN
  • 0390-6078
  • 1592-8721
Cited by
47
References
2
Language
en

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