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Prevalence and Duration of Acute Loss of Smell or Taste in COVID-19 Patients
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Initially, acute loss of smell (anosmia) and taste (ageusia) was not considered important symptoms for coronavirus disease 2019 (COVID-19).To determine the prevalence of these symptoms and to evaluate their diagnostic significance, we (approximately 150 physicians of the Daegu Medical Association) prospectively collected data of cases of anosmia and ageusia from March 8, 2020, via telephone interview among 3,191 patients in Daegu, Korea.Acute anosmia or ageusia was observed in 15.3% (488/3,191) patients in the early stage of COVID-19 and in 15.7% (367/2,342) patients with asymptomatic-to-mild disease severity.Their prevalence was significantly more common among females and younger individuals (P = 0.01 and P < 0.001, respectively).Most patients with anosmia or ageusia recovered within 3 weeks.The median time to recovery was 7 days for both symptoms.Anosmia and ageusia seem to be part of important symptoms and clues for the diagnosis of COVID-19, particularly in the early stage of the disease.
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“recovery from COVID-related anosmia often occurs over weeks (11, 17, 18)”
From Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia (2020) · cites this paper as [17]
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“Any reasonable pathophysiological mechanism for COVID-19-associated anosmia must account for the high penetrance of smell disorders relative to endemic viruses (12, 91, 92), the apparent suddenness of smell loss that can precede the development of other symptoms (11, 13), and the transient nature of dysfunction in many patients (11, 17, 18); definitive identification of the disease mechanisms”
From Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia (2020) · cites this paper as [17]
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Metadata
- Authors
- Lee, Y., Min, P., Lee, S., & Kim, S.-W.
- Affiliations
- Daegu Medical Association (KR)
- Daegu Medical Association, Daegu, Korea.
- Kyungpook National University (KR)
- Corresponding author
- Kim, Shin-Woo
- Venue
- Journal of Korean Medical Science
- Publisher
- XMLink
- Published
- 2020
- Volume
- 35
- Issue
- 18
- Pages
- e174-e174
- ISSN
- 1011-8934 (ISSN-L)
- 1598-6357
- PMC
- PMC7211515
- OpenAlex
- W3023547764
- Cited by
- 528
- References
- 17
- Citations by year
- 2026: 4 · 2025: 12 · 2024: 38 · 2023: 58 · 2022: 116 · 2021: 178 · 2020: 122
- FWCI
- 41.58
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Journal of Korean Medical Science (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Dermatology › Dermatological and COVID-19 studies
- Keywords
- COVID-19 pandemic, anosmia, ageusia, symptom prevalence, symptom duration, symptom recovery, early diagnosis, asymptomatic patients, Daegu
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, COVID-19 Testing, Adult, Ageusia, Olfaction Disorders, Female, Humans, Male, Pneumonia, Viral, Smell, Taste, Prevalence, Polymerase Chain Reaction, Age Distribution, Sex Distribution, Coronavirus, Coronavirus Infections, Clinical Laboratory Techniques, Republic of Korea, Pandemics
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