Epidemiology and prevention of hepatitis B virus infection
Open accessAbstract
Hepatitis B virus (HBV) infection has been a major global cause of morbidity and mortality. The recognition of the problem led to a worldwide effort to reduce transmission of HBV through routine infant vaccination. HBV infection is the most common cause of chronic liver diseases and hepatocellular carcinoma in Korea. After hepatitis B vaccine era, seroprevalence of hepatits B surface antigen is decreasing, particularly in children. Hepatitis B vaccine is remarkably safe and shows high immunogenicity. Universal childhood immunization with three doses of hepatitis B vaccine in the first year of life is a highly effective method for prevention and control of hepatitis B.
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Mother-to-child transmission at birth is responsible for the majority of chronic hepatitis B infections and adverse outcomes.
“Mother-to-child transmission at birth is responsible for the majority of chronic infections and adverse outcomes because there is a high risk of persistent infection when exposure occurs in the neonatal period [2].”
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Cited by
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Gilder, M. E., Pateekhum, C., Hashmi, A., Aramrat, C., Aung, K. K., Miket, W., Chu, C. S., Win, D., Bierhoff, M., Wiwattanacharoen, W., et al. (2022) · International Journal for Equity in Health · doi:10.1186/s12939-022-01802-5 · Cited by 9 · see citing works
- Authors
- Kwon, S. Y., & Lee, C. H.
- Affiliations
- Konkuk University (KR)
- Corresponding author
- Lee, Chang Hong
- ORCID
- Kwon, So Young
- Venue
- The Korean Journal of Hepatology
- Published
- 2011
- Volume
- 17
- Issue
- 2
- Pages
- 87
- ISSN
- 1738-222X (ISSN-L)
- PMC
- PMC3304633
- OpenAlex
- W2170771423
- Cited by
- 171
- References
- 71
- Citations by year
- 2026: 7 · 2025: 10 · 2024: 21 · 2023: 16 · 2022: 19 · 2021: 16 · 2020: 5 · 2019: 11 · 2018: 7 · 2017: 13 · 2016: 4 · 2015: 9 · 2014: 5 · 2013: 17 · 2012: 10
- FWCI
- 1.20
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- The Korean Journal of Hepatology (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Hepatitis B Virus Studies
- Health Sciences › Medicine › Emergency Medicine › Intramuscular injections and effects
- Health Sciences › Medicine › Hepatology › Hepatitis C virus research
- Keywords
- hepatitis B virus, hepatitis B vaccine, infant immunization, childhood immunization, seroprevalence, hepatitis B surface antigen, chronic liver disease, hepatocellular carcinoma, vaccine safety, immunogenicity
- MeSH terms
- Hepatitis B, Hepatitis B Antibodies, Hepatitis B virus, Humans, Vaccination, Hepatitis B Vaccines
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