p38 MAPK Signaling in Osteoblast Differentiation

Interleukin-17 modulates myoblast cell migration by inhibiting urokinase type plasminogen activator expression through p38 mitogen-activated protein kinase

Kocić, J., Santibanez, J. F., Krstić, J., Mojsilović, S. B., Ilić, V. L., & Bugarski, D. S. (2012) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2012.11.010 · Cited by 27

Hypoxia and vitamin D differently contribute to leptin and dickkopf-related protein 2 production in human osteoarthritic subchondral bone osteoblasts

Bouvard, B., Abed, É., Yelehe‐Okouma, M., Bianchi, A., Mainard, D., Netter, P., Jouzeau, J., Lajeunesse, D., & Reboul, P. (2014) · Arthritis Research & Therapy · doi:10.1186/s13075-014-0459-3 · Cited by 27

Prevention of Trabecular Bone Loss Induced by Estrogen Deficiency by a Selective p38α Inhibitor

Caverzasio, J., Higgins, L. S., & Ammann, P. (2008) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.080410 · Cited by 27

Cold exposure stimulates lipid metabolism, induces inflammatory response in the adipose tissue of mice and promotes the osteogenic differentiation of BMMSCs via the p38 MAPK pathway in vitro.

Nie, Y., Yan, Z., Yan, W., Xia, Q., & Zhang, Y. (2015) · PubMed Central · Cited by 27

Hypoxia induces osteogenic/angiogenic responses of bone marrow‐derived mesenchymal stromal cells seeded on bone‐derived scaffolds via ERK1/2 and p38 pathways

Zhou, Y., Guan, X., Wang, H., Zhu, Z., Li, C., Wu, S., & Yu, H. (2013) · Biotechnology and Bioengineering · doi:10.1002/bit.24827 · Cited by 26

Suppression of p38α MAPK Signaling in Osteoblast Lineage Cells Impairs Bone Anabolic Action of Parathyroid Hormone

Thouverey, C., & Caverzasio, J. (2015) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2762 · Cited by 26

8-Prenylkaempferol accelerates osteoblast maturation through bone morphogenetic protein-2/p38 pathway to activate Runx2 transcription

Chiou, W., Lee, C., Liao, J.-F., et al. (2010) · Life Sciences · doi:10.1016/j.lfs.2010.12.009 · Cited by 25

Hypoxia Regulates the Proliferation and Osteogenic Differentiation of Human Periodontal Ligament Cells Under Cyclic Tensile Stress via Mitogen‐Activated Protein Kinase Pathways

Li, L., Han, M., Li, S., Xu, Y., & Wang, L. (2013) · Journal of Periodontology · doi:10.1902/jop.2013.130048 · Cited by 25

Phosphorylation of RSK2 at Tyr529 by FGFR2-p38 enhances human mammary epithelial cells migration

Czaplińska, D., Turczyk, L., Grudowska, A., Mieszkowska, M., Lipińska, A. D., Składanowski, A. C., Zaczek, A. J., Romańska, H., & Sądej, R. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2014.06.022 · Cited by 23

Efficacy of a nitrogen-containing bisphosphonate, minodronate, in conjunction with a p38 mitogen activated protein kinase inhibitor or doxorubicin against malignant bone tumor cells

Kubo, T., Shimose, S., Matsuo, T., Sakai, A., & Ochi, M. (2007) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-007-0580-y · Cited by 22

Knockdown of Sec8 enhances the binding affinity of c‐Jun N‐terminal kinase ( JNK )‐interacting protein 4 for mitogen‐activated protein kinase kinase 4 ( MKK 4) and suppresses the phosphorylation of MKK 4, p38, and JNK , thereby inhibiting apoptosis

Tanaka, T., Iino, M., & Goto, K. (2014) · FEBS Journal · doi:10.1111/febs.13063 · Cited by 22

Separating myoblast differentiation from muscle cell fusion using IGF-I and the p38 MAP kinase inhibitor SB202190

Gardner, S., Gross, S. M., David, L. L., Klimek, J. E., & Rotwein, P. S. (2015) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00184.2015 · Cited by 22

PlexinA2 mediates osteoblast differentiation via regulation of Runx2

Oh, J.-E., Kim, H. J., Kim, W.-S., Lee, Z. H., Ryoo, H.-M., Hwang, S. J., Lee, Y., & Kim, H.-H. (2012) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.1471 · Cited by 21

The effect of neuropeptide Y on brown-like adipocyte's differentiation and activation

Wan, Y., Xue, R., Wang, Y., Zhang, Q., Huang, S., Wu, W., Ye, H., Zhang, Z., & Li, Y. (2014) · Peptides · doi:10.1016/j.peptides.2014.10.018 · Cited by 21

Oscillatory fluid flow elicits changes in morphology, cytoskeleton and integrin-associated molecules in MLO-Y4 cells, but not in MC3T3-E1 cells

Xu, H., Zhang, J., Wu, J., Guan, Y., Weng, Y., & Shang, P. (2012) · Biological Research · doi:10.4067/s0716-97602012000200008 · Cited by 20

MKP1-dependent PTH modulation of bone matrix mineralization in female mice is osteoblast maturation stage specific and involves P-ERK and P-p38 MAPKs

Mahalingam, C. D., Sampathi, B. R., Sharma, S., Datta, T., Das, V., Abou‐Samra, A., & Datta, N. S. (2012) · Journal of Endocrinology · doi:10.1530/joe-12-0372 · Cited by 20

p38 mitogen-activated protein (MAP) kinase but not p44/p42 MAP kinase is involved in prostaglandin E1-induced vascular endothelial growth factor synthesis in osteoblasts

Tokuda, H., Kozawa, O., Miwa, M., & Uematsu, T. (2001) · Journal of Endocrinology · doi:10.1677/joe.0.1700629 · Cited by 20

Sambucus Williamsii Hance Promotes MC3T3‐E1 Cells Proliferation and Differentiation via BMP‐2/Smad/p38/JNK/Runx2 Signaling Pathway

Yang, B., Lin, X., Yang, C., Tan, J., Li, W., & Kuang, H. (2015) · Phytotherapy Research · doi:10.1002/ptr.5482 · Cited by 19

Contribution of S6K1/MAPK Signaling Pathways in the Response to Oxidative Stress: Activation of RSK and MSK by Hydrogen Peroxide

Siebel, A. M., Cubillos‐Rojas, M., Santos, R. C. V., Schneider, T., Bonan, C. D., Bartrons, R., Ventura, F., de Oliveira, J. R., & Rosa, J. L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0075523 · Cited by 19

Role of mitogen‐activated protein kinase in osteoblast differentiation

Lin, F., Chang, J. B., & Brigman, B. E. (2010) · Journal of Orthopaedic Research® · doi:10.1002/jor.21222 · Cited by 18

Molecular and mechano-biology of collagen gel contraction mediated by human MG-63 cells: involvement of specific intracellular signaling pathways and the cytoskeleton

Parreno, J., & Hart, D. A. (2009) · Biochemistry and Cell Biology · doi:10.1139/o09-052 · Cited by 18

Involvement of Rho-kinase in prostaglandin F2α-stimulated interleukin-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts

Minamitani, C., Otsuka, T., Takai, S., Matsushima‐Nishiwaki, R., Adachi, S., Hanai, Y., Mizutani, J., Tokuda, H., & Kozawa, O. (2008) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2008.05.011 · Cited by 17

Loss of p38δ mitogen-activated protein kinase expression promotes oesophageal squamous cell carcinoma proliferation, migration and anchorage-independent growth

O'Callaghan, C., Fanning, L. J., Houston, A. M., & Barry, Ó. P. (2013) · International Journal of Oncology · doi:10.3892/ijo.2013.1968 · Cited by 17

(2S)-7,4′-dihydroxy-8-prenylflavan stimulates adipogenesis and glucose uptake through p38MAPK pathway in 3T3-L1 cells

Ji, J., Zhu, J., Hu, X., et al. (2015) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2015.03.072 · Cited by 14

p38α function in osteoblasts influences adipose tissue homeostasis

Rodríguez-Carballo, E., Gámez, B., Méndez‐Lucas, A., Sánchez‐Feutrie, M., Antonio Zorzano, A., Bartrons, R., Alcántara, S., Perales, J. C., & Ventura, F. (2014) · The FASEB Journal · doi:10.1096/fj.14-261891 · Cited by 14

Cell Cycle and Apoptosis Regulatory Protein (CARP)-1 is Expressed inOsteoblasts and Regulated by PTH

Sharma, S., Mahalingam, C. D., Das, V., Jamal, S., Levi, E., Rishi, A. K., & Datta, N. S. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.05.136 · Cited by 14

New insights in osteogenic differentiation revealed by mass spectrometric assessment of phosphorylated substrates in murine skin mesenchymal cells

Halcsik, E., Forni, M. F., Fujita, A., et al. (2013) · BMC Cell Biology · doi:10.1186/1471-2121-14-47 · Cited by 13

Regulation of myogenic activation of p38 MAPK by TACE-mediated TNFα release

Li, Y.-P., Niu, A., & Wen, Y. (2014) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2014.00021 · Cited by 13

Diversity and versatility of p38 kinase signalling in health and disease

Canovas, B., & Nebreda, A. R. (2021) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-00322-w · Cited by 657

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis

Zengini, E., Hatzikotoulas, K., Tachmazidou, I., Steinberg, J., Hartwig, F. P., Southam, L., Hackinger, S., Boer, C. G., Styrkarsdottir, U., Gilly, A., et al. (2018) · Nature Genetics · doi:10.1038/s41588-018-0079-y · Cited by 319

Human mesenchymal stem cell derived exosomes enhance cell‐free bone regeneration by altering their miRNAs profiles

Zhai, M., Zhu, Y., Yang, M., & Mao, C. (2020) · Advanced Science · doi:10.1002/advs.202001334 · Cited by 277

Activating; ‐catenin/Pax6 axis negatively regulates osteoclastogenesis by selectively inhibiting phosphorylation of p38/MAPK

Jie, Z., Shen, S., Zhao, X., Xu, W., Zhang, X., Huang, B., Tang, P., Qin, A., Fan, S., & Xie, Z. (2019) · The FASEB Journal · doi:10.1096/fj.201801977r · Cited by 22

Osteogenic Effects of Ion Released from Biodegradable Metallic Magnesium and Calcium Coating

Miyake, R., Shimabukuro, M., Terauchi, M., Marukawa, E., & Kawashita, M. (2025) · Advanced Biology · doi:10.1002/adbi.202500401 · Cited by 5