The DOI matches its Crossref record; 86 of the 87 references it cites were found in a registry or an index.
Roles of PLODs in Collagen Synthesis and Cancer Progression
Open accessAbstract
genes. Expression of PLODs is regulated by multiple cytokines, transcription factors and microRNAs. Dysregulation of PLODs promotes cancer progression and metastasis, suggesting that targeting PLODs is potential strategy for cancer treatment. Here, we summarize the recent progress in the investigation of function and regulation of PLODs in normal tissue development and disease progression, especially in cancer.
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2 retracted
Gilkes, D. M., Bajpai, S. K., Chaturvedi, P., Wirtz, D., & Semenza, G. L. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.442939 · Cited by 473
RetractedProcollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis
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RetractedMolecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin
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Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
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Tumour-educated macrophages promote tumour progression and metastasis
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Collagen reorganization at the tumor-stromal interface facilitates local invasion
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Collagen density promotes mammary tumor initiation and progression
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Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma
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Dynamic interplay between the collagen scaffold and tumor evolution
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Vitamin C-Sources, Physiological Role, Kinetics, Deficiency, Use, Toxicity, and Determination
Doseděl, M., Jirkovský, E., Macáková, K., Krčmová, L., Javorská, L., Pourová, J., Mercolini, L., Remião, F., Nováková, L., Mladěnka, P., et al. (2021) · Nutrients · doi:10.3390/nu13020615 · Cited by 553
The Extracellular Matrix: Its Composition, Function, Remodeling, and Role in Tumorigenesis
Dzobo, K., & Dandara, C. (2023) · Biomimetics · doi:10.3390/biomimetics8020146 · Cited by 228
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Metadata
- Authors
- Qi, Y., & Xu, R.
- Affiliations
- University of Kentucky (US)
- Corresponding author
- Xu, Ren
- ORCID
- Xu, Ren
- Venue
- Frontiers in Cell and Developmental Biology
- Publisher
- Frontiers Media SA
- Published
- 2018-06-28
- Volume
- 6
- Pages
- 66-66
- ISSN
- 2296-634X (ISSN-L)
- PMC
- PMC6031748
- OpenAlex
- W2808438085
- Cited by
- 248
- References
- 87
- Citations by year
- 2026: 20 · 2025: 31 · 2024: 28 · 2023: 26 · 2022: 42 · 2021: 38 · 2020: 48 · 2019: 13 · 2018: 1
- FWCI
- 2.67
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Frontiers in Cell and Developmental Biology (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- UKnowledge (University of Kentucky) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Institutes of Health (1R01CA207772, 1R01CA215095, 1R21CA209045)
- U.S. Department of Defense (W81XWH-15-1-0052)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › TGF-β signaling in diseases
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Proteoglycans and glycosaminoglycans research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Protease and Inhibitor Mechanisms
- Keywords
- collagen synthesis, tumor progression, metastasis, gene expression regulation, cytokines, transcription factors, microRNA, histogenesis, cancer therapy targets
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