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Knockdown of GPSM1 Inhibits the Proliferation and Promotes the Apoptosis of B-Cell Acute Lymphoblastic Leukemia Cells by Suppressing the ADCY6-RAPGEF3-JNK Signaling Pathway

Zhang, Y., Zhou, B., Sun, J., He, Q., & Zhao, Y. (2021) · Pathology & Oncology Research · doi:10.3389/pore.2021.643376 · Cited by 10 · see citing works

Oncogenic signaling pathways in pancreatic ductal adenocarcinoma

Agrawal, R., & Natarajan, K. N. (2023) · Advances in cancer research · doi:10.1016/bs.acr.2023.02.006 · Cited by 10 · see citing works

Broad Ultrastructural and Transcriptomic Changes Underlie the Multinucleated Giant Hemocyte Mediated Innate Immune Response against Parasitoids

Cinege, G., Magyar, L. B., Kovács, A. L., Lerner, Z., Juhász, G., Lukacsovich, D., Winterer, J., Lukácsovich, T., Hegedüs, Z., Kurucz, É., et al. (2021) · Journal of Innate Immunity · doi:10.1159/000520110 · Cited by 10 · see citing works

Nacα protects the larval fat body from cell death by maintaining cellular proteostasis in Drosophila

Yamada, T., Yoshinari, Y., Tobo, M., Habara, O., & Nishimura, T. (2023) · Nature Communications · doi:10.1038/s41467-023-41103-1 · Cited by 7 · see citing works

Magnolin ameliorates acetaminophen-induced liver injury in mice via modulating the MAPK pathway and lipid metabolism

Yao, T., Wu, Y., Fu, L., & Li, L. (2025) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2025.117264 · Cited by 9 · see citing works

Stress pathway outputs are encoded by pH-dependent clustering of kinase components

Didan, Y., Ghomlaghi, M., Nguyen, L. K., & Ng, D. C. H. (2024) · Nature Communications · doi:10.1038/s41467-024-50638-w · Cited by 9 · see citing works

An unscheduled switch to endocycles induces a reversible senescent arrest that impairs growth of the Drosophila wing disc

Huang, Y., Hesting, L. L., & Calvi, B. R. (2024) · PLoS Genetics · doi:10.1371/journal.pgen.1011387 · Cited by 7 · see citing works

Glia instruct axon regeneration via a ternary modulation of neuronal calcium channels in Drosophila

Trombley, S., Powell, J. R., Guttipatti, P., Matamoros, A. J., Lin, X., O’Harrow, T. C. D. G., Steinschaden, T., Miles, L., Wang, Q., Wang, S., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-42306-2 · Cited by 8 · see citing works

A feedback loop that drives cell death and proliferation and its defect in intestinal stem cells

Sulekh, S., Ikegawa, Y., Naito, S., Oji, A., Hiratani, I., & Yoo, S. K. (2024) · Life Science Alliance · doi:10.26508/lsa.202302238 · Cited by 8 · see citing works

Modulation of Hippo signaling by Mnat9 N-acetyltransferase for normal growth and tumorigenesis in Drosophila

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Melamine induced changes in histopathology of the main organs and transcriptional levels of MAPK signaling genes in kidneys of female mice

Yang, W., Liang, C., Zhang, X., Xiaohui, T., Ren, C., Chen, S., Wang, J., & Zhang, J. (2021) · Environmental Toxicology · doi:10.1002/tox.23424 · Cited by 8 · see citing works

PTP61F Mediates Cell Competition and Mitigates Tumorigenesis

Marca, J. E. L., Willoughby, L. F., Allan, K., Portela, M., Goh, P. K., Tiganis, T., & Richardson, H. E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222312732 · Cited by 7 · see citing works

dGLYAT modulates Gadd45-mediated JNK activation and cell invasion

Xu, M., Ren, P., Tian, J., Xiao, L., Hu, P., Chen, P., Li, W., & Xue, L. (2022) · Cell Division · doi:10.1186/s13008-022-00080-5 · Cited by 7 · see citing works

PTP10D-mediated cell competition is not obligately required for elimination of polarity-deficient clones

Gerlach, S. U., de Vreede, G., & Bilder, D. H. (2022) · Biology Open · doi:10.1242/bio.059525 · Cited by 7 · see citing works

Gbb Regulates Blood Cell Proliferation and Differentiation through JNK and EGFR Signaling Pathways in the Drosophila Lymph Gland

Zhang, W., Wang, D., Si, J., Jin, L. H., & Hao, Y. (2023) · Cells · doi:10.3390/cells12040661 · Cited by 7 · see citing works

A Drosophila chemical screen reveals synergistic effect of MEK and DGKα inhibition in Ras-driven cancer

Marca, J. E. L., Ely, R. W., Diepstraten, S. T., Burke, P., Kelly, G. L., Humbert, P. O., & Richardson, H. E. (2023) · Disease Models & Mechanisms · doi:10.1242/dmm.049769 · Cited by 7 · see citing works

Interaction between non-coding RNAs and JNK in human disorders

Ghafouri‐Fard, S., Abak, A., Mohaqiq, M., Shoorei, H., & Taheri, M. N. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111497 · Cited by 7 · see citing works

The JNK and Hippo pathways control epithelial integrity and prevent tumor initiation by regulating an overlapping transcriptome

Mitchell, K. A., Vissers, J. H. A., Pojer, J. M., Brooks, E., Hilmi, A. J. S., Papenfuss, A. T., Schröder, J., & Harvey, K. F. (2024) · Current Biology · doi:10.1016/j.cub.2024.07.060 · Cited by 6 · see citing works

MLN2238 exerts its anti-tumor effects via regulating ROS/JNK/mitochondrial signaling pathways in intrahepatic cholangiocarcinoma

Xu, H., Xu, G., Xu, Q., Xu, C., Zhou, X., Bai, Y., Yin, L., Ding, Y., & Wang, W. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1040847 · Cited by 6 · see citing works

The Case of the Scribble Polarity Module in Asymmetric Neuroblast Division in Development and Tumorigenesis

Carmena, A. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21082865 · Cited by 6 · see citing works

Basic and Translational Models of Cooperative Oncogenesis

Richardson, H. E., Cordero, J. B., & Grifoni, D. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21165919 · Cited by 6 · see citing works

Xenobiotic responses of Drosophila melanogaster to insecticides with different modes of action and entry

Gao, L., Zang, X., Qiao, H., Moussian, B., & Wang, Y. (2022) · Archives of Insect Biochemistry and Physiology · doi:10.1002/arch.21958 · Cited by 6 · see citing works

Elimination of oncogenic cells that regulate epithelial homeostasis in Drosophila

Ohsawa, S. (2019) · Development Growth & Differentiation · doi:10.1111/dgd.12604 · Cited by 6 · see citing works

Identification of the Wallenda JNKKK as an Alk suppressor reveals increased competitiveness of Alk-expressing cells

Wolfstetter, G., Pfeifer, K., Backman, M., Masudi, T., Mendoza-García, P., Chen, S., Sonnenberg, H. C., Sukumar, S. K., Uçkun, E., Varshney, G. K., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-70890-6 · Cited by 6 · see citing works

Mud Loss Restricts Yki-Dependent Hyperplasia in Drosophila Epithelia

Parra, A. S., & Johnston, C. A. (2020) · Journal of Developmental Biology · doi:10.3390/jdb8040034 · Cited by 5 · see citing works

Regeneration following tissue necrosis is mediated by non-apoptotic caspase activity

Klemm, J. W., Hazel, C. V., & Harris, R. E. (2025) · eLife · doi:10.7554/elife.101114.3 · Cited by 5 · see citing works

Activation of the Drosophila innate immune system accelerates growth in cooperation with oncogenic Ras

Brutscher, F., Germani, F., Hausmann, G., Jutz, L., & Basler, K. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3003068 · Cited by 5 · see citing works

Cell-death induced immune response and coagulopathy promote cachexia in DrosophilaPreprint

Singh, A., Hu, Y., Lopes, R., Lane, L., Woldemichael, H. B., Xu, C., Udeshi, N. D., Carr, S. A., & Perrimon, N. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.07.631515 · Cited by 5 · see citing works

A JAK/STAT-Pdk1-S6K axis bypasses systemic growth restrictions to promote regeneration

Maya, A. V., Neuhaus, L., Nogay, L., Singh, A., Heckmann, L., Grass, I., Buescher, J. M., Kierdorf, K., & Classen, A.-K. (2025) · Nature Communications · doi:10.1038/s41467-025-66995-z · Cited by 4 · see citing works

Cell death in regeneration and cell turnover: Lessons from planarians and Drosophila

Adell, T., Cebrià, F., Abril, J. F., Araújo, S. J., Corominas, M., Morey, M., Serras, F., & González‐Estévez, C. (2025) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2025.103605 · Cited by 7 · see citing works

A threshold level of JNK activates damage-responsive enhancers via JAK/STAT to promote tissue regeneration

Quinn, J. W., Lee, M. C., Hazel, C. V., Wilson, M. A., & Harris, R. E. (2025) · Development · doi:10.1242/dev.204632 · Cited by 4 · see citing works

Wallenda-Nmo Axis Regulates Growth via Hippo Signaling

Wang, X., Liang, H., Xu, W., & Ma, X. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.658288 · Cited by 4 · see citing works

Distinct roles of Bendless in regulating FSC niche competition and daughter cell differentiation

Tatapudy, S., Peralta, J., & Nystul, T. G. (2021) · Development · doi:10.1242/dev.199630 · Cited by 3 · see citing works

Loss of the spectraplakin gene Short stop induces a DNA damage response in Drosophila epithelia

Dewey, E. B., Parra, A. S., & Johnston, C. A. (2020) · Scientific Reports · doi:10.1038/s41598-020-77159-y · Cited by 4 · see citing works

Regeneration following tissue necrosis is mediated by non-apoptotic caspase activityPreprint

Klemm, J. W., Hazel, C. V., & Harris, R. E. (2024) · eLife · doi:10.7554/elife.101114 · Cited by 4 · see citing works

Dissecting the Molecular Mechanism of 10-HDA Biosynthesis: Role of Acyl-CoA Delta(11) Desaturase and Transcriptional Regulators in Honeybee Mandibular Glands

Li, Y., Zhang, X., Xia, Z., & Hao, Y. (2025) · Insects · doi:10.3390/insects16060563 · Cited by 3 · see citing works

Pp1-87B/PPP1CC-JNK axis integrates apoptosis and ferroptosis-like cell death to regulate cell competition and tumorigenesis

Kong, D., Li, Z., Zhao, S., Yang, X., Zheng, J., Guo, Y., Xu, W., Gao, H., Guo, H., Zhang, Q., et al. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116240 · Cited by 3 · see citing works

Effects of TmTak1 silencing on AMP production as an Imd pathway component in Tenebrio molitor

Hwang, S. H., Jang, H. A., Kojour, M. A. M., Yun, K., Lee, Y. S., Han, Y. S., & Jo, Y. H. (2023) · Scientific Reports · doi:10.1038/s41598-023-45978-4 · Cited by 3 · see citing works

JNK Kinase regulates cachexia like syndrome in scribble knockdown tumor model of Drosophila melanogaster

Kumar, R., & Srikrishna, S. (2024) · Developmental Biology · doi:10.1016/j.ydbio.2024.09.005 · Cited by 3 · see citing works

Macrophage-like Blood Cells Are Involved in Inter-Tissue Communication to Activate JAK/STAT Signaling, Inducing Antitumor Turandot Proteins in Drosophila Fat Body via the TNF-JNK Pathway

Kinoshita, J., Kinoshita, Y., Nomura, T., & Inoue, Y. H. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252313110 · Cited by 3 · see citing works

Epigenomic Changes in Ostrinia Moths Under Elevated Pupal and Adult Temperature

Velikaneye, B. A., & Kozak, G. M. (2025) · Molecular Ecology · doi:10.1111/mec.17676 · Cited by 3 · see citing works

Apoptosis-resistant cells drive compensatory proliferation via cell-autonomous and non-autonomous functions of the initiator caspase Dronc

Braun, T., Afgin, N., Sapozhnikov, L., Sivan, E., Bergmann, A., Baena-López, L. A., Yacobi-Sharon, K., & Arama, E. (2025) · Nature Communications · doi:10.1038/s41467-025-65996-2 · Cited by 4 · see citing works

Drosophila DAxud1 Has a Repressive Transcription Activity on Hsp70 and Other Heat Shock Genes

Zúñiga-Hernández, J. M., Meneses, C., Bastías, M., Allende, M. L., & Glavic, Á. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087485 · Cited by 3 · see citing works

A conserved mechanism for JNK-mediated loss of Notch function in advanced prostate cancer

Wang, C.-W., Clémot, M., Hashimoto, T., Diaz, J. A., Goins, L. M., Goldstein, A. S., Nagaraj, R., & Banerjee, U. K. (2023) · Science Signaling · doi:10.1126/scisignal.abo5213 · Cited by 3 · see citing works

NF-κB signaling driven by oncogenic Ras contributes to tumorigenesis in a Drosophila carcinoma model

Dillard, C., Teles-Reis, J., Jain, A., Antunes, M. G., Ruiz-Duran, P., Qi, Y., Borgne, R. L., Jasper, H., & Rusten, T. E. (2025) · PLoS Biology · doi:10.1371/journal.pbio.3002663 · Cited by 4 · see citing works

LncRNAs and IgA nephropathy: underlying molecular pathways and clinical applications

Alimohammadi, M., Kahkesh, S., Abbasi, A., Hashemi, M., Khoshnazar, S. M., Taheriazam, A., & Hushmandi, K. (2025) · Clinical and Experimental Medicine · doi:10.1007/s10238-025-01660-9 · Cited by 2 · see citing works

Regnases play a crucial role in guarding against cancer development

Wawro, M., Kochan, J. A., & Kasza, A. (2025) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2025.189352 · Cited by 2 · see citing works

Spoonbill positively regulates JNK signalling mediated apoptosis in Drosophila melanogaster

Das, R., Pandey, P., Maurya, B., Pradhan, P., Sinha, D., Mukherjee, A., & Mutsuddi, M. (2023) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2023.151300 · Cited by 2 · see citing works

Spatio-temporal pattern of c-Jun N-terminal kinase isoforms in the cochleae of C57BL/6J mice with presbycusis

Ding, R., Pan, Y., Chen, K., Zou, T., Zhang, A., Guo, D., Ji, P., Fan, C., Ye, B., & Xiang, M. (2023) · Hearing Research · doi:10.1016/j.heares.2023.108784 · Cited by 2 · see citing works

Importance of targeting various cell signaling pathways in solid cancers

Ghosh, C., & Hu, J. (2024) · International review of cytology · doi:10.1016/bs.ircmb.2024.02.002 · Cited by 2 · see citing works

Loss of non-muscle myosin II Zipper leads to apoptosis-induced compensatory proliferation in Drosophila

Verma, D., Sarkar, B., Singh, J., Singh, A., Mutsuddi, M., & Mukherjee, A. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2025.119939 · Cited by 2 · see citing works

Chitinase-like proteins promoting tumorigenesis through disruption of cell polarity via enlarged endosomal vesicles

Khalili, D., Kunc, M., Herbrich, S., Müller, A. M., & Theopold, U. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1170122 · Cited by 2 · see citing works

Mutual repression between JNK/AP-1 and JAK/STAT stratifies cell behaviors during tissue regenerationPreprint

Jaiswal, J., Engesser, R., Peyrotón, A. A., Weichselberger, V., Crucianelli, C., Grass, I., Timmer, J., & Classen, A.-K. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.05.11.491445 · Cited by 2 · see citing works

Oncogenic Ras-driven Dorsal/NF-κB signaling contributes to tumorigenesis in a Drosophila carcinoma modelPreprint

Dillard, C., Teles-Reis, J., Jain, A., Borgne, R. L., Jasper, H., & Rusten, T. E. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.08.593126 · Cited by 2 · see citing works

Activation of the innate immune system accelerates growth in cooperation with oncogenic RasPreprint

Brutscher, F., Germani, F., Hausmann, G., Jutz, L., & Basler, K. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.23.595555 · Cited by 2 · see citing works

Mitotic polarity oscillation promotes epithelial tumor progressionPreprint

Jeyanathan, G., Cao, M., Pellikka, M., Robinson, S., Talukder, P., Ghorayeb, V., & Tepaß, U. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.02.06.636979 · Cited by 2 · see citing works

A Tumour-Specific Molecular Network Promotes Tumour Growth in <i>Drosophila</i> by Enforcing a JNK-YKI Feedforward Loop

Waghmare, I., Gangwani, K., Rai, A., Singh, A., & Kango-Singh, M. (2023) · doi:10.1101/2023.10.18.561369 · Cited by 1 · see citing works

Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a <i>Drosophila</i> tumor model

Uhlirova, M., Jasper, H., & Bohmann, D. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504170102 · Cited by 134 · see citing works

Short-term activation of the Jun N-terminal kinase pathway in apoptosis-deficient cells of Drosophila induces tumorigenesis

Pinal, N., Martín, M. J., Medina, I., & Morata, G. (2018) · Nature Communications · doi:10.1038/s41467-018-04000-6 · Cited by 58 · see citing works

JNK signaling is converted from anti- to pro-tumor pathway by Ras-mediated switch of Warts activity

Enomoto, M., Kizawa, D., Ohsawa, S., & Igaki, T. (2015) · Developmental Biology · doi:10.1016/j.ydbio.2015.05.001 · Cited by 74 · see citing works

Investigation of JNK signaling pathway in a drosophila tumor model

Zhang, L. (2021) · doi:10.14711/thesis-991012936365703412

The Emerging Roles of JNK Signaling in Drosophila Stem Cell Homeostasis

Herrera, S. C., & Bach, E. A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115519 · Cited by 38 · see citing works